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GO-CAM-like Models Report — Xenbase

Model ID Title Date modified Contributors Pipeline result Result details Warnings 
6446bfcb00001289
 Fzd3 regulation of Vangl2 in planar cell polarity establishment 2026-03-13 Malcolm Fisher filtered Model has at least one activity with no causal relations
4 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: protein binding [GO:0005515] (molecular_function) —causally upstream of or within→ establishment of planar polarity [GO:0001736] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of→ establishment of planar polarity [GO:0001736] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: prickle3.L Xlae [Xenbase:XB-GENE-940037] (information biomacromolecule) —part of→ plasma membrane protein complex [GO:0098797] (cellular_component)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: protein serine/threonine kinase activity [GO:0004674] (molecular_function) —causally upstream of negative effect→ establishment of planar polarity [GO:0001736] (biological_process) 
5fadbcf000000317
 Fzd3 function in Cranial neural crest cells 2026-03-12 Malcolm Fisher success
15 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: apoptotic process [GO:0006915] (biological_process) —occurs in→ cranial neural crest [XAO:0001001] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Rho-dependent protein serine/threonine kinase activity [GO:0072518] (molecular_function) —causally upstream of or within positive effect→ contact inhibition [GO:0060242] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: JUN kinase activity [GO:0004705] (molecular_function) —causally upstream of or within positive effect→ cell migration [GO:0016477] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Wnt signaling pathway, planar cell polarity pathway [GO:0060071] (biological_process) —occurs in→ cranial neural crest [XAO:0001001] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: cell migration [GO:0016477] (biological_process) —occurs in→ cranial neural crest [XAO:0001001] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: positive regulation of transcription by RNA polymerase II [GO:0045944] (biological_process) —causally upstream of negative effect→ apoptotic process [GO:0006915] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: RNA binding [GO:0003723] (molecular_function) —causally upstream of positive effect→ neural crest cell migration [GO:0001755] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: neural crest cell migration [GO:0001755] (biological_process) —occurs in→ cranial neural crest [XAO:0001001] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: neural crest cell fate specification [GO:0014036] (biological_process) —occurs in→ neural plate border [XAO:0004104] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Rho-dependent protein serine/threonine kinase activity [GO:0072518] (molecular_function) —causally upstream of or within positive effect→ cell migration [GO:0016477] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: positive regulation of transcription by RNA polymerase II [GO:0045944] (biological_process) —causally upstream of positive effect→ cell population proliferation [GO:0008283] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: positive regulation of transcription by RNA polymerase II [GO:0045944] (biological_process) —occurs in→ nucleus [GO:0005634] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: non-canonical Wnt signaling pathway [GO:0035567] (biological_process) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: cell population proliferation [GO:0008283] (biological_process) —occurs in→ cranial neural crest [XAO:0001001] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: JUN kinase activity [GO:0004705] (molecular_function) —causally upstream of or within positive effect→ contact inhibition [GO:0060242] (biological_process) 
6205c24300000508
 tbx5 in Xenopus lung and heart development. 2023-10-31 Christina James-Zorn, Malcolm Fisher filtered Model has at least one activity with no causal relations
4 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Wnt signaling pathway [GO:0016055] (biological_process) —part of→ heart development [GO:0007507] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of or within positive effect→ Wnt signaling pathway [GO:0016055] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of positive effect→ Wnt signaling pathway [GO:0016055] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Wnt signaling pathway [GO:0016055] (biological_process) —part of→ lung development [GO:0030324] (biological_process) 
627d95ee00002159
 Xenopus trio, and cdh11 in development and neural cell migration. 2023-03-16 Malcolm Fisher success
7 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: cell migration [GO:0016477] (biological_process) —part of→ embryonic cranial skeleton morphogenesis [GO:0048701] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: lamellipodium assembly [GO:0030032] (biological_process) —part of→ cell migration [GO:0016477] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: actin filament polymerization [GO:0030041] (biological_process) —part of→ filopodium assembly [GO:0046847] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: GTPase activity [GO:0003924] (molecular_function) —causally upstream of or within positive effect→ actin filament polymerization [GO:0030041] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: actin filament polymerization [GO:0030041] (biological_process) —part of→ lamellipodium assembly [GO:0030032] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: filopodium assembly [GO:0046847] (biological_process) —part of→ cell migration [GO:0016477] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: cell migration [GO:0016477] (biological_process) —occurs in→ migratory neural crest cell [XAO:0004069] (anatomical entity) 
635b1e3e00002235
 Caveolin 1 is required for axonal outgrowth of motor neurons in Xenopus 2022-11-09 Malcolm Fisher success
10 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of or within→ swimming behavior [GO:0036269] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: actin filament organization [GO:0007015] (biological_process) —part of→ sarcomere organization [GO:0045214] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: lamellipodium assembly [GO:0030032] (biological_process) —occurs in→ motor neuron [XAO:0004217] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of or within negative effect→ lamellipodium assembly [GO:0030032] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of or within→ actin filament organization [GO:0007015] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: neuron development [GO:0048666] (biological_process) —occurs in→ motor neuron [XAO:0004217] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of or within→ neuron development [GO:0048666] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of or within positive effect→ neuron development [GO:0048666] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of or within negative effect→ neuron development [GO:0048666] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: neuron development [GO:0048666] (biological_process) —causally upstream of or within→ swimming behavior [GO:0036269] (biological_process) 
62900b6400000156
 Xenopus tmem79 role in regulation of frizzled in wnt signaling. 2022-06-15 Malcolm Fisher filtered Model has at least one activity with no causal relations
5 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: deubiquitinase activity [GO:0101005] (molecular_function) —causally upstream of or within negative effect→ Wnt receptor catabolic process [GO:0038018] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Wnt receptor catabolic process [GO:0038018] (biological_process) —has input→ fzd1.L Xlae [Xenbase:XB-GENE-865493] (information biomacromolecule)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Wnt receptor catabolic process [GO:0038018] (biological_process) —causally upstream of or within negative effect→ Wnt signaling pathway [GO:0016055] (biological_process)
  • SKIPPED_FACT: Subject 'Wnt receptor catabolic process [GO:0038018] (biological_process)' has 'has input' relationship to 'fzd1.L Xlae [Xenbase:XB-GENE-865493] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Wnt signaling pathway [GO:0016055] (biological_process) —causally upstream of or within→ head development [GO:0060322] (biological_process) 
61e0e55600001095
 ddx3x in wnt signaling and craniofacial development in Xenopus 2022-02-01 Malcolm Fisher filtered Model has at least one activity with no causal relations
8 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of or within→ positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: RNA helicase activity [GO:0003724] (molecular_function) —causally upstream of or within→ post-transcriptional regulation of gene expression [GO:0010608] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of or within→ neural crest cell development [GO:0014032] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Wnt signaling pathway [GO:0016055] (biological_process) —part of→ neural crest cell development [GO:0014032] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: post-transcriptional regulation of gene expression [GO:0010608] (biological_process) —has input→ rac1 Xtro [Xenbase:XB-GENE-489008] (information biomacromolecule)
  • SKIPPED_FACT: Subject 'post-transcriptional regulation of gene expression [GO:0010608] (biological_process)' has 'has input' relationship to 'rac1 Xtro [Xenbase:XB-GENE-489008] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of or within→ embryonic cranial skeleton morphogenesis [GO:0048701] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0051897] (biological_process) —part of→ Wnt signaling pathway [GO:0016055] (biological_process)
Release date
2026-08-28
Pipeline name
pipeline-from-goa
Pipeline branch
main
Generated on
2026-08-29T14:10:14+00:00
gocam-py version
0.12.0.post65.dev0+8382d25a