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GO-CAM-like Models Report — WB

Model ID Title Date modified Contributors Pipeline result Result details Warnings 
62f58d8800001738
 Gut Microbiota tryptophan metabolism: Regulation of intestinal transit by 5-hydroxy-L-tryptophan(Human-E.coli) 2026-08-10 Cristina Casals, Kimberly Van Auken success 
5b91dbd100002057
 Antifungal innate immune response in the hypodermis via MAPK cascade (C. elegans) 2026-07-03 Kimberly Van Auken, Marie-Claire Harrison success
1 warning
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: antifungal innate immune response [GO:0061760] (biological_process) —occurs in→ hypodermis [WBbt:0005733] (anatomical entity) 
5b318d0900000583
 C. elegans PERK-mediated unfolded protein response 2026-07-03 Kimberly Van Auken, Marie-Claire Harrison filtered Model has at least one activity with no causal relations
1 warning
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —causally upstream of or within→ PERK-mediated unfolded protein response [GO:0036499] (biological_process) 
568b0f9600000284
 Antibacterial innate immune response in the intestine via MAPK cascade (C. elegans) 2026-07-01 Kimberly Van Auken, Marie-Claire Harrison success
2 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —part of→ detection of bacterium [GO:0016045] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: molecular_function [GO:0003674] (molecular_function) —directly positively regulates→ protein serine/threonine kinase activity [GO:0004674] (molecular_function) 
60ad85f700002621
 Transcription Factor - Target Gene NR3C1 BLM FES HDDC3 MAN2A2 2026-06-05 Colin Logie, Kimberly Van Auken, Yves Snijckers success 
5f46c3b700001031
 MYD88-dependent TLR4 signaling pathway leading to NF-kappa-B activation (Human) 2026-04-27 Cristina Casals, Kimberly Van Auken, Pascale Gaudet, Patrick Masson success 
61f34dd300001044
 Yeast ergosterol 2026-04-21 Kimberly Van Auken, Marc Feuermann, Sylvain Poux success 
61bcf0b700000560
 tRNA methylation by METTL6 and regulation by SARS1-binding (Human) 2026-04-17 Sharan Prakash, Sylvain Poux success 
62b4ffe300000906
 Poxvirus-OPG065 inhibition of ISG15 conjugation (Human-Poxvirus) 2026-04-13 Kimberly Van Auken, Patrick Masson, Sylvain Poux success 
5323da1800000002
 NEDD4-model1 2026-03-24 Kimberly Van Auken, Pascale Gaudet, Paul Thomas, Rama Balakrishnan, Seth Carbon success 
627d95ee00000955
 Chondroitin sulfate catabolic process (Mouse) 2026-03-12 David Hill, Kimberly Van Auken success
12 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553] (molecular_function) —occurs in→ lysosome [GO:0005764] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553] (molecular_function) —provides input for→ N-acetylgalactosamine-6-sulfatase activity [GO:0043890] (molecular_function)
  • SKIPPED_FACT: Subject 'hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553] (molecular_function)' has 'has input' relationship to 'chondroitin sulfate [CHEBI:37397] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: transport [GO:0006810] (biological_process) —has primary input→ chondroitin sulfate [CHEBI:37397] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: transport [GO:0006810] (biological_process) —causally upstream of positive effect→ chondroitin sulfate proteoglycan catabolic process [GO:0030207] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553] (molecular_function) —has input→ chondroitin sulfate [CHEBI:37397] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: chondroitin sulfate [CHEBI:37397] (chemical entity) —part of→ proteoglycan [CHEBI:37396] (information biomacromolecule)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: transport [GO:0006810] (biological_process) —has target end location→ lysosome [GO:0005764] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553] (molecular_function) —part of→ chondroitin sulfate proteoglycan catabolic process [GO:0030207] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: hydrolase activity, hydrolyzing O-glycosyl compounds [GO:0004553] (molecular_function) —provides input for→ N-acetylgalactosamine-4-sulfatase activity [GO:0003943] (molecular_function)
  • SKIPPED_FACT: Subject 'transport [GO:0006810] (biological_process)' has 'has primary input' relationship to 'chondroitin sulfate [CHEBI:37397] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: transport [GO:0006810] (biological_process) —has target start location→ extracellular region [GO:0005576] (anatomical entity) 
63894f2500000740
 FIP200 ubiquitination by TRIM21 leading to autophagy inhibition (Human) 2026-03-12 Kimberly Van Auken, Patrick Masson success 
59dc728000000351
 GPCR - AC activating 2026-02-26 Kimberly Van Auken, Pascale Gaudet success
1 warning
  • SKIPPED_FACT: 'adenylate cyclase activity [GO:0004016] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189] (biological_process)' 
5e72450500004237
 SARS-COV2/cycle from polyprotein processing to viral genome replication (SRAS-COV-2) 2026-02-26 Kimberly Van Auken, Patrick Masson success
2 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: viral RNA genome replication [GO:0039694] (biological_process) —occurs in→ double membrane vesicle viral factory [GO:0039718] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: double membrane vesicle viral factory assembly [GO:0140526] (biological_process) —part of→ lipid binding [GO:0008289] (molecular_function) 
667dfe8d00000011
 CD48-CD244 ligand receptor binding in NK cell activation (Human) 2025-12-17 Guilaine Argoud-Puy, Kimberly Van Auken success 
5ae3b0f600001520
 Involvement of YAP-1, the Homolog of Yes-Associated Protein, in the Wnt-Mediated Neuronal Polarization in Caenorhabditis elegans. 2025-12-08 Kimberly Van Auken success
3 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: establishment of cell polarity [GO:0030010] (biological_process) —occurs in→ ALM [WBbt:0005406] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: nucleus [GO:0005634] (anatomical entity) —part of→ PLM [WBbt:0005490] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: yap-1 Cele [WB:WBGene00008748] (information biomacromolecule) —located in→ nucleus [GO:0005634] (anatomical entity) 
5a5fc23a00000137
 ZDB-PUB-170709-3 clocka in mesoderm development and primitive hematopoiesis 2025-10-24 Kimberly Van Auken, Leyla Ruzicka, Sabrina Toro success
7 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: positive regulation of transcription by RNA polymerase II [GO:0045944] (biological_process) —has input→ gomodel:5a5fc23a00000137/5b91dbd100001405
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: nodal signaling pathway [GO:0038092] (biological_process) —causally upstream of positive effect→ mesoderm development [GO:0007498] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: positive regulation of transcription by RNA polymerase II [GO:0045944] (biological_process) —causally upstream of positive effect→ molecular_function [GO:0003674] (molecular_function)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: mesoderm development [GO:0007498] (biological_process) —causally upstream of positive effect→ primitive hemopoiesis [GO:0060215] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981] (molecular_function) —has input→ gomodel:5a5fc23a00000137/5b91dbd100001405
  • MISSING_TERM: While processing 'DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981] (molecular_function)' has input 'gomodel:5a5fc23a00000137/5b91dbd100001405', the object could not be mapped to a term; skipping this fact.
  • MISSING_TERM: While processing 'positive regulation of transcription by RNA polymerase II [GO:0045944] (biological_process)' has input 'gomodel:5a5fc23a00000137/5b91dbd100001405', the object could not be mapped to a term; skipping this fact. 
6606056e00000903
 Activation of the integrated stress response via activation of EIF2AK1/HRI by DELE1 in response to mitochondrial stress (Human) 2025-10-03 Kimberly Van Auken, Pascale Gaudet, Sylvain Poux success 
5ed1aab700000290
 Sodium transport in kidney 2025-07-28 David Hill, Kimberly Van Auken success
6 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: cortical collecting duct [EMAPA:28130] (anatomical entity) —part of→ metanephros [EMAPA:17373] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: biological_process [GO:0008150] (biological_process) —causally upstream of negative effect→ sodium ion transport [GO:0006814] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: plasma membrane [GO:0005886] (anatomical entity) —part of→ kidney cortex collecting duct epithelial cell [CL:1000549] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: sodium ion transport [GO:0006814] (biological_process) —occurs in→ plasma membrane [GO:0005886] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: kidney cortex collecting duct epithelial cell [CL:1000549] (anatomical entity) —part of→ cortical collecting duct [EMAPA:28130] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: metanephros [EMAPA:17373] (anatomical entity) —part of→ renal system [UBERON:0001008] (anatomical entity) 
62f58d8800001680
 Gut Microbiota tryptophan metabolism: Regulation of intestinal epithelial cell homesotasis by Indole-AhR (Human-E.coli) 2025-07-09 Cristina Casals, Kimberly Van Auken success 
62900b6400002523
 ZDHHC7 regulates estrogen receptor activity at plasma membrane (Human) 2025-02-07 Kimberly Van Auken, Lionel Breuza success 
62b4ffe300002896
 Poxvirus-OPG043 inhibition of host PKR (Human-Poxvirus) 2023-11-09 Kimberly Van Auken, Patrick Masson success 
5b528b1100000489
 XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity 2023-08-01 Kimberly Van Auken, Marie-Claire Harrison success
6 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: IRE1-mediated unfolded protein response [GO:0036498] (biological_process) —occurs in→ intestine [WBbt:0005772] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO:0000977] (molecular_function) —positively regulates→ IRE1-mediated unfolded protein response [GO:0036498] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: synaptic vesicle exocytosis [GO:0016079] (biological_process) —causally upstream of positive effect→ cell-cell signaling [GO:0007267] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: IRE1-mediated unfolded protein response [GO:0036498] (biological_process) —negatively regulates→ determination of adult lifespan [GO:0008340] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: IRE1-mediated unfolded protein response [GO:0036498] (biological_process) —occurs in→ neuron [WBbt:0003679] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: cell-cell signaling [GO:0007267] (biological_process) —causally upstream of positive effect→ RNA endonuclease activity [GO:0004521] (molecular_function) 
5b91dbd100002039
 DAF-16 Defense Response pathway C. elegans Intestine 2023-03-16 Marie-Claire Harrison success 
636d9ce800000749
 Positive regulation of cold-induced thermogenesis in brown adipose tissue by LETMD1. (Human) 2023-03-16 Cristina Casals, Kimberly Van Auken success 
5745387b00001516
 Canonical glycolysis 1 (Mouse) 2023-03-15 David Hill, Sharan Prakash success 
5fadbcf000000000
 Neuronal IRE-1 and C. elegans germline apoptosis 2022-09-22 Kimberly Van Auken success
1 warning
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: protein serine/threonine kinase activity [GO:0004674] (molecular_function) —causally upstream of positive effect→ intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332] (biological_process) 
5b318d0900000302
 IRE1-mediated unfolded protein response (Mouse) 2022-04-19 David Hill, Kimberly Van Auken, Marie-Claire Harrison filtered Model has at least one activity with no causal relations 
5b91dbd100002241
 Antifungal innate immune response in the hypodermis via transforming growth factor beta receptor signaling pathway (C. elegans) 2021-07-26 Kimberly Van Auken, Marie-Claire Harrison filtered Model has at least one activity with no causal relations
4 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: positive regulation of transcription by RNA polymerase II [GO:0045944] (biological_process) —causally upstream of positive effect→ molecular_function [GO:0003674] (molecular_function)
  • SKIPPED_FACT: Subject 'positive regulation of transcription by RNA polymerase II [GO:0045944] (biological_process)' has 'has input' relationship to 'cnc-2 Cele [WB:WBGene00000556] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: positive regulation of transcription by RNA polymerase II [GO:0045944] (biological_process) —has input→ cnc-2 Cele [WB:WBGene00000556] (information biomacromolecule)
  • SKIPPED_FACT: 'DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'defense response to fungus [GO:0050832] (biological_process)' 
5b91dbd100001993
 ZIP-2 Defense Response Pathway in the C. elegans Intestine 2021-05-12 Kimberly Van Auken, Marie-Claire Harrison success
3 warnings
  • SKIPPED_FACT: 'DNA-binding transcription factor activity [GO:0003700] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'defense response to Gram-negative bacterium [GO:0050829] (biological_process)'
  • SKIPPED_FACT: 'molecular_function [GO:0003674] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'antibacterial innate immune response [GO:0140367] (biological_process)'
  • SKIPPED_FACT: 'molecular_function [GO:0003674] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'antibacterial innate immune response [GO:0140367] (biological_process)' 
5b91dbd100001959
 FSHR-1 Defense Pathway in the C. elegans intestine 2019-10-15 Kimberly Van Auken, Marie-Claire Harrison success
Release date
2026-08-28
Pipeline name
pipeline-from-goa
Pipeline branch
main
Generated on
2026-08-29T14:10:14+00:00
gocam-py version
0.12.0.post65.dev0+8382d25a