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GO-CAM-like Models Report — SGD

Model ID Title Date modified Contributors Pipeline result Result details Warnings 
YeastPathways_TRPSYN-PWY-1
 L-tryptophan biosynthesis - imported from: Saccharomyces Genome Database 2026-08-25 Curators at SGD, Stacia Engel success 
YeastPathways_YEAST-RIBOSYN-PWY
 riboflavin, FMN and FAD biosynthesis - imported from: Saccharomyces Genome Database 2026-08-25 Curators at SGD, Stacia Engel success
19 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '5-amino-6-(5-phosphoribitylamino)uracil(2-) [CHEBI:58421] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ 5-amino-6-(D-ribitylamino)uracil [CHEBI:15934] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ 5-amino-6-(5-phosphoribitylamino)uracil(2-) [CHEBI:58421] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'hydrogenphosphate [CHEBI:43474] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '5-amino-6-(D-ribitylamino)uracil [CHEBI:15934] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ ammonium [CHEBI:28938] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'ammonium [CHEBI:28938] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ flavin-containing compound biosynthetic process [GO:0042727] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ hydrogenphosphate [CHEBI:43474] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '5-amino-6-(5-phosphoribitylamino)uracil(2-) [CHEBI:58421] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate(2-) [CHEBI:58890] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate(2-) [CHEBI:58890] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 5-amino-6-(5-phosphoribitylamino)uracil(2-) [CHEBI:58421] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity) 
YeastPathways_PWY3O-743
 salvage pathways of guanine, xanthine and their nucleosides - imported from: Saccharomyces Genome Database 2026-08-25 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations 
YeastPathways_YEAST-RNT-SALV
 salvage pathways of pyrimidine ribonucleotides - imported from: Saccharomyces Genome Database 2026-08-25 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-781
 sulfate assimilation pathway - imported from: Saccharomyces Genome Database 2026-08-25 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-6-1
 dehydro-D-arabinono-1,4-lactone biosynthesis - imported from: Saccharomyces Genome Database 2026-08-24 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-450
 phosphatidylcholine biosynthesis I - imported from: Saccharomyces Genome Database 2026-08-24 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-259
 phospholipid biosynthesis II (Kennedy pathway) - imported from: Saccharomyces Genome Database 2026-08-24 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-6122-1
 5-aminoimidazole ribonucleotide biosynthesis II - imported from: Saccharomyces Genome Database 2026-08-14 Curators at SGD, Stacia Engel success 
YeastPathways_CITRUL-BIO2-PWY
 citrulline biosynthesis - imported from: Saccharomyces Genome Database 2026-08-14 Curators at SGD, Stacia Engel success 
YeastPathways_GLYCLEAV-PWY
 glycine cleavage - imported from: Saccharomyces Genome Database 2026-08-14 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_HOMOSER-THRESYN-PWY
 L-threonine biosynthesis - imported from: Saccharomyces Genome Database 2026-08-14 Curators at SGD, Stacia Engel success 
YeastPathways_IPPSYN-PWY
 mevalonate pathway - imported from: Saccharomyces Genome Database 2026-08-14 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-922
 mevalonate pathway I - imported from: Saccharomyces Genome Database 2026-08-14 Curators at SGD, Stacia Engel success 
YeastPathways_POLYAMSYN-YEAST-PWY
 superpathway of polyamine biosynthesis - imported from: Saccharomyces Genome Database 2026-08-14 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-214
 tryptophan degradation - imported from: Saccharomyces Genome Database 2026-08-14 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-8
 xylose metabolism - imported from: Saccharomyces Genome Database 2026-08-13 Curators at SGD, Stacia Engel success 
YeastPathways_BIOTIN-SYNTHESIS-PWY
 biotin biosynthesis - imported from: Saccharomyces Genome Database 2026-08-11 Curators at SGD, Stacia Engel success 
YeastPathways_HEME-BIOSYNTHESIS-II
 heme <i>b</i> biosynthesis I (aerobic) - imported from: Saccharomyces Genome Database 2026-08-10 Curators at SGD, Edith Wong, Rob Nash, Stacia Engel success 
YeastPathways_HISTSYN-PWY
 L-histidine biosynthesis - imported from: Saccharomyces Genome Database 2026-08-10 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_HOMOSERSYN-PWY
 L-homoserine biosynthesis - imported from: Saccharomyces Genome Database 2026-08-10 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-4106
 NAD salvage pathway IV (from nicotinamide riboside) - imported from: Saccharomyces Genome Database 2026-08-10 Curators at SGD, Rob Nash, Stacia Engel success 
YeastPathways_PWY3O-1874
 p-aminobenzoate biosynthesis - imported from: Saccharomyces Genome Database 2026-08-10 Curators at SGD, Rob Nash, Stacia Engel success 
YeastPathways_ALLANTOINDEG-PWY
 superpathway of allantoin degradation in yeast - imported from: Saccharomyces Genome Database 2026-08-10 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-50
 tetrapyrrole biosynthesis - imported from: Saccharomyces Genome Database 2026-08-10 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-6543
 4-aminobenzoate biosynthesis - imported from: Saccharomyces Genome Database 2026-08-05 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-6147
 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I - imported from: Saccharomyces Genome Database 2026-08-05 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-15
 chitin biosynthesis - imported from: Saccharomyces Genome Database 2026-08-05 Curators at SGD, Stacia Engel success 
YeastPathways_HEXPPSYN-PWY-2
 hexaprenyl diphosphate biosynthesis - imported from: Saccharomyces Genome Database 2026-08-05 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-1801
 palmitoleate biosynthesis - imported from: Saccharomyces Genome Database 2026-08-05 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-6614
 tetrahydrofolate biosynthesis - imported from: Saccharomyces Genome Database 2026-08-05 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-1801-1
 formaldehyde oxidation II (glutathione-dependent) - imported from: Saccharomyces Genome Database 2026-08-04 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_AERO-GLYCEROL-CAT-PWY
 glycerol degradation - imported from: Saccharomyces Genome Database 2026-08-04 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-4108
 L-tyrosine degradation III - imported from: Saccharomyces Genome Database 2026-08-04 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-5194-1
 siroheme biosynthesis - imported from: Saccharomyces Genome Database 2026-08-04 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-5340
 sulfate activation (for sulfonation) - imported from: Saccharomyces Genome Database 2026-08-04 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-5123
 <i>trans, trans</i>-farnesyl diphosphate biosynthesis - imported from: Saccharomyces Genome Database 2026-08-03 Curators at SGD, Stacia Engel success 
YeastPathways_CYSTEINE-SYN2-PWY
 cysteine biosynthesis from homocysteine - imported from: Saccharomyces Genome Database 2026-08-03 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-123
 dolichyl phosphate D-mannose biosynthesis - imported from: Saccharomyces Genome Database 2026-08-03 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY-6075-1
 ergosterol biosynthesis I - imported from: Saccharomyces Genome Database 2026-08-03 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_GLUTATHIONESYN-PWY
 glutathione biosynthesis - imported from: Saccharomyces Genome Database 2026-08-03 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWYQT-4432
 glutathione degradation - imported from: Saccharomyces Genome Database 2026-08-03 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_HOMOCYSDEGR-PWY-1
 L-cysteine biosynthesis III (from L-homocysteine) - imported from: Saccharomyces Genome Database 2026-08-03 Curators at SGD, Rob Nash, Stacia Engel success 
YeastPathways_BSUBPOLYAMSYN-PWY
 spermidine biosynthesis I - imported from: Saccharomyces Genome Database 2026-08-03 Curators at SGD, Stacia Engel success 
YeastPathways_TRESYN-PWY
 trehalose biosynthesis I - imported from: Saccharomyces Genome Database 2026-08-03 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_UDPNAGSYN-YEAST-PWY
 UDP-N-acetylglucosamine biosynthesis - imported from: Saccharomyces Genome Database 2026-08-03 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY-5703
 urea degradation I - imported from: Saccharomyces Genome Database 2026-08-03 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY-5344
 L-homocysteine biosynthesis - imported from: Saccharomyces Genome Database 2026-07-31 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_GLYCOLYSIS
 glycolysis I (from glucose 6-phosphate) - imported from: Saccharomyces Genome Database 2026-07-30 Curators at SGD, David Hill, Stacia Engel, Suzi Aleksander success 
YeastPathways_PWY3O-188
 aerobic respiration, electron transport chain - imported from: Saccharomyces Genome Database 2026-07-27 Curators at SGD, Stacia Engel, Suzi Aleksander filtered Model has at least one activity with no causal relations 
YeastPathways_PROSYN-PWY
 L-proline biosynthesis I - imported from: Saccharomyces Genome Database 2026-07-23 Curators at SGD, Stacia Engel success
10 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ L-glutamic 5-semialdehyde zwitterion [CHEBI:58066] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ L-proline biosynthetic process [GO:0055129] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ (S)-1-pyrroline-5-carboxylate [CHEBI:17388] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '(S)-1-pyrroline-5-carboxylate [CHEBI:17388] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'L-glutamic 5-semialdehyde zwitterion [CHEBI:58066] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity) 
YeastPathways_PROUT-PWY
 L-proline degradation - imported from: Saccharomyces Genome Database 2026-07-23 Curators at SGD, Stacia Engel success
10 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ L-proline catabolic process [GO:0006562] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '(S)-1-pyrroline-5-carboxylate [CHEBI:17388] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ (S)-1-pyrroline-5-carboxylate [CHEBI:17388] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ L-glutamic 5-semialdehyde zwitterion [CHEBI:58066] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'L-glutamic 5-semialdehyde zwitterion [CHEBI:58066] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_PHOSLIPSYN2-PWY-1
 phospholipid biosynthesis - imported from: Saccharomyces Genome Database 2026-07-23 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PLPSAL-PWY
 pyridoxal 5'-phosphate salvage I - imported from: Saccharomyces Genome Database 2026-07-23 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations 
YeastPathways_PWY3O-1
 salvage pathways of purines and their nucleosides - imported from: Saccharomyces Genome Database 2026-07-23 Curators at SGD, Edith Wong, Stacia Engel filtered Model has at least one activity with no causal relations 
YeastPathways_PWY3O-13
 superpathway of glutamate biosynthesis - imported from: Saccharomyces Genome Database 2026-07-23 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-6125
 superpathway of guanosine nucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database 2026-07-23 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations 
YeastPathways_DENOVOPURINE2-PWY
 superpathway of purine nucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database 2026-07-23 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-17
 thiamine biosynthesis - imported from: Saccharomyces Genome Database 2026-07-23 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_YEAST-FAO-PWY
 fatty acid oxidation pathway - imported from: Saccharomyces Genome Database 2026-07-22 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-4158
 superpathway of NAD biosynthesis - imported from: Saccharomyces Genome Database 2026-07-22 Curators at SGD, Edith Wong, Stacia Engel filtered Model has at least one activity with no causal relations
8 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate [CHEBI:994] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ NAD+ biosynthetic process [GO:0009435] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'quinolinic acid [CHEBI:16675] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ quinolinic acid [CHEBI:16675] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate [CHEBI:994] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_DENOVOPURINE3-PWY
 de novo biosynthesis of purine nucleotides - imported from: Saccharomyces Genome Database 2026-07-21 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-242
 phosphatidylinositol phosphate biosynthesis - imported from: Saccharomyces Genome Database 2026-07-21 Curators at SGD, Stacia Engel success 
YeastPathways_SPHINGOLIPID-SYN-PWY-1
 sphingolipid biosynthesis (yeast) - imported from: Saccharomyces Genome Database 2026-07-21 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-697
 folate interconversions - imported from: Saccharomyces Genome Database 2026-07-20 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY-2201
 folate transformations I - imported from: Saccharomyces Genome Database 2026-07-20 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations
46 warnings
  • SKIPPED_FACT: Subject 'trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function)' has 'has output' relationship to 'trimethylsulfonium [CHEBI:17434] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function) —has output→ trimethylsulfonium [CHEBI:17434] (chemical entity)
  • SKIPPED_FACT: Subject 'formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function)' has 'has output' relationship to 'tetrahydrofolate [CHEBI:67016] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function) —has output→ CHEBI:17908
  • SKIPPED_FACT: Subject 'methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function)' has 'has input' relationship to 'CHEBI:17513', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function) —has output→ tetrahydrofolate [CHEBI:67016] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function) —part of→ folate cycle [GO:0035999] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function) —has input→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function)' has 'has output' relationship to 'CHEBI:17908', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'methionine synthase activity [GO:0008705] (molecular_function)' has 'has output' relationship to 'L-methionine zwitterion [CHEBI:57844] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methionine synthase activity [GO:0008705] (molecular_function) —has input→ L-homocysteine zwitterion [CHEBI:58199] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function) —has output→ formate [CHEBI:15740] (chemical entity)
  • SKIPPED_FACT: Subject 'methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function)' has 'has input' relationship to '5,10-methylenetetrahydrofolic acid [CHEBI:20502] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function)' has 'has output' relationship to 'chemical entity [CHEBI:24431] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function) —has input→ 5,10-methylenetetrahydrofolic acid [CHEBI:20502] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function) —has input→ gomodel:cdb5c9f2-2ddf-434b-abbd-126ddd178d6c_1.5.1.20-RXN
  • SKIPPED_FACT: Subject 'formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function)' has 'has input' relationship to '10-formyltetrahydrofolyl-(Glu)n polyanion [CHEBI:134413] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'methionine synthase activity [GO:0008705] (molecular_function)' has 'has input' relationship to 'L-homocysteine zwitterion [CHEBI:58199] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function) —has input→ 10-formyltetrahydrofolyl-(Glu)n polyanion [CHEBI:134413] (chemical entity)
  • SKIPPED_FACT: Subject 'methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function) —has input→ dimethyl sulfide [CHEBI:17437] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function) —has output→ 5-methyltetrahydrofolate [CHEBI:20612] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methionine synthase activity [GO:0008705] (molecular_function) —has output→ tetrahydrofolate [CHEBI:67016] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methionine synthase activity [GO:0008705] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function) —has input→ water [CHEBI:15377] (chemical entity)
  • MISSING_TERM: While processing 'glycine dehydrogenase (decarboxylating) activity [GO:0004375] (molecular_function)' has input 'gomodel:7b5d7437-1d95-4821-b858-704981fff8d4_2.1.1.19-RXN', the object could not be mapped to a term; skipping this fact.
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: glycine dehydrogenase (decarboxylating) activity [GO:0004375] (molecular_function) —has input→ gomodel:7b5d7437-1d95-4821-b858-704981fff8d4_2.1.1.19-RXN
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function) —part of→ folate cycle [GO:0035999] (biological_process)
  • SKIPPED_FACT: Subject 'formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methionine synthase activity [GO:0008705] (molecular_function) —part of→ folate cycle [GO:0035999] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function) —has output→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function)' has 'has input' relationship to 'dimethyl sulfide [CHEBI:17437] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methionine synthase activity [GO:0008705] (molecular_function) —has output→ L-methionine zwitterion [CHEBI:57844] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function) —has input→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function) —has output→ chemical entity [CHEBI:24431] (chemical entity)
  • MISSING_TERM: While processing 'trimethylsulfonium-tetrahydrofolate N-methyltransferase activity [GO:0047147] (molecular_function)' has input 'gomodel:cdb5c9f2-2ddf-434b-abbd-126ddd178d6c_1.5.1.20-RXN', the object could not be mapped to a term; skipping this fact.
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function) —has input→ CHEBI:17513
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function) —part of→ folate cycle [GO:0035999] (biological_process)
  • SKIPPED_FACT: Subject 'methylenetetrahydrofolate reductase (ferredoxin) activity [GO:0033738] (molecular_function)' has 'has output' relationship to '5-methyltetrahydrofolate [CHEBI:20612] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'methionine synthase activity [GO:0008705] (molecular_function)' has 'has output' relationship to 'tetrahydrofolate [CHEBI:67016] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'formyltetrahydrofolate deformylase activity [GO:0008864] (molecular_function)' has 'has output' relationship to 'formate [CHEBI:15740] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_GLUCONEO-PWY-1
 gluconeogenesis I - imported from: Saccharomyces Genome Database 2026-07-20 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-4031
 glycogen biosynthesis - imported from: Saccharomyces Genome Database 2026-07-20 Curators at SGD, David Hill, Stacia Engel success
2 warnings
  • MISSING_TERM: While processing '1,4-alpha-glucan branching enzyme activity [GO:0003844] (molecular_function)' has input 'gomodel:67e75762-a418-4123-9f1e-62da7a229873_RXN-7668', the object could not be mapped to a term; skipping this fact.
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: 1,4-alpha-glucan branching enzyme activity [GO:0003844] (molecular_function) —has input→ gomodel:67e75762-a418-4123-9f1e-62da7a229873_RXN-7668 
YeastPathways_PWY3O-6336
 superpathway of fatty acid biosynthesis, saturated - imported from: Saccharomyces Genome Database 2026-07-20 Curators at SGD, Edith Wong, Stacia Engel success
13 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —has output→ coenzyme A(4-) [CHEBI:57287] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'palmitoyl hydrolase activity [GO:0098599] (molecular_function)' has 'has output' relationship to 'hexadecanoate [CHEBI:7896] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —has input→ palmitoyl-CoA(4-) [CHEBI:57379] (chemical entity)
  • SKIPPED_FACT: Subject 'palmitoyl hydrolase activity [GO:0098599] (molecular_function)' has 'has output' relationship to 'coenzyme A(4-) [CHEBI:57287] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'palmitoyl hydrolase activity [GO:0098599] (molecular_function)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —part of→ fatty acid elongation, saturated fatty acid [GO:0019367] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —has output→ hexadecanoate [CHEBI:7896] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyltransferase activity [GO:0016409] (molecular_function) —provides input for→ palmitoyl hydrolase activity [GO:0098599] (molecular_function)
  • SKIPPED_FACT: Subject 'palmitoyl hydrolase activity [GO:0098599] (molecular_function)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —has output→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'palmitoyl hydrolase activity [GO:0098599] (molecular_function)' has 'has input' relationship to 'palmitoyl-CoA(4-) [CHEBI:57379] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity) 
YeastPathways_PENTOSE-P-PWY
 pentose phosphate pathway - imported from: Saccharomyces Genome Database 2026-07-17 Curators at SGD, Stacia Engel success 
YeastPathways_BRANCHED-CHAIN-AA-SYN-PWY-1
 superpathway of branched chain amino acid biosynthesis - imported from: Saccharomyces Genome Database 2026-07-17 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-20
 folate polyglutamylation - imported from: Saccharomyces Genome Database 2026-07-16 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-4109
 isoleucine degradation - imported from: Saccharomyces Genome Database 2026-07-16 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY-5697
 allantoin degradation to ureidoglycolate I (urea producing) - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel success 
YeastPathways_ARGDEG-YEAST-PWY
 arginine degradation (aerobic) - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations
13 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '(S)-1-pyrroline-5-carboxylate [CHEBI:17388] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: pyrroline-5-carboxylate reductase activity [GO:0004735] (molecular_function) —provides input for→ Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: proline dehydrogenase activity [GO:0004657] (molecular_function) —provides input for→ Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —provides input for→ L-glutamate gamma-semialdehyde dehydrogenase (NAD+) activity [GO:0003842] (molecular_function)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ L-arginine catabolic process [GO:0006527] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'L-glutamic 5-semialdehyde zwitterion [CHEBI:58066] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ (S)-1-pyrroline-5-carboxylate [CHEBI:17388] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ L-glutamic 5-semialdehyde zwitterion [CHEBI:58066] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity) 
YeastPathways_SO4ASSIM-PWY
 assimilatory sulfate reduction I - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_TRIGLSYN-PWY
 diacylglycerol and triacylglycerol biosynthesis - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel success
8 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ 2-monoglyceride [CHEBI:17389] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'triacyl-sn-glycerol [CHEBI:64615] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ triacyl-sn-glycerol [CHEBI:64615] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ triglyceride biosynthetic process [GO:0019432] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 1,2-diacyl-sn-glycerol [CHEBI:17815] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '1,2-diacyl-sn-glycerol [CHEBI:17815] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '2-monoglyceride [CHEBI:17389] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_PWY3O-1565
 dolichyl glucosyl phosphate biosynthesis - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-4300
 ethanol degradation - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-10
 fatty acid biosynthesis, initial steps - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel success 
YeastPathways_FASYN-ELONG2-PWY
 fatty acid elongation - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_GLUT-REDOX2-PWY
 glutathione-glutaredoxin redox reactions - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel success
10 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'information biomacromolecule [CHEBI:33695] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ glutathione disulfide(2-) [CHEBI:58297] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'glutathionate(1-) [CHEBI:57925] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ information biomacromolecule [CHEBI:33695] (information biomacromolecule)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ glutathionate(1-) [CHEBI:57925] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'information biomacromolecule [CHEBI:33695] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ glutathione metabolic process [GO:0006749] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ information biomacromolecule [CHEBI:33695] (information biomacromolecule)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'glutathione disulfide(2-) [CHEBI:58297] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_GLYOXYLATE-BYPASS
 glyoxylate cycle - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-6123-1
 inosine-5'-phosphate biosynthesis I - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_ARG-PRO-PWY
 L-arginine degradation VI (arginase 2 pathway) - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations
12 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ L-glutamic 5-semialdehyde zwitterion [CHEBI:58066] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: L-ornithine transaminase activity [GO:0004587] (molecular_function) —provides input for→ Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ L-arginine catabolic process [GO:0006527] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ (S)-1-pyrroline-5-carboxylate [CHEBI:17388] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '(S)-1-pyrroline-5-carboxylate [CHEBI:17388] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'L-glutamic 5-semialdehyde zwitterion [CHEBI:58066] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —provides input for→ pyrroline-5-carboxylate reductase activity [GO:0004735] (molecular_function) 
YeastPathways_ASPARAGINE-BIOSYNTHESIS-1
 L-asparagine biosynthesis I - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel success 
YeastPathways_THRESYN-PWY
 superpathway of L-threonine biosynthesis - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel, Suzi Aleksander success 
YeastPathways_PWY3O-6635
 superpathway of phosphatidate biosynthesis - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel success 
YeastPathways_PHOS-PWY
 superpathway of phosphatidic acid and phospholipid biosynthesis - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Edith Wong, Stacia Engel success
1 warning
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: phosphatidylethanolamine N-methyltransferase activity [GO:0004608] (molecular_function) —provides input for→ CDP-ethanolamine(1-) [CHEBI:57876] (chemical entity) 
YeastPathways_PWY0-162
 superpathway of pyrimidine ribonucleotides <i>de novo</i> biosynthesis - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-7
 superpathway of threonine biosynthesis - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel, Suzi Aleksander success 
YeastPathways_PWY3O-4105
 valine degradation - imported from: Saccharomyces Genome Database 2026-07-15 Curators at SGD, Stacia Engel success 
YeastPathways_ASPARAGINE-DEG2-PWY
 asparagine degradation - imported from: Saccharomyces Genome Database 2026-07-14 Curators at SGD, Stacia Engel success 
YeastPathways_ASPBIO-PWY
 aspartate biosynthesis - imported from: Saccharomyces Genome Database 2026-07-14 Curators at SGD, Stacia Engel success 
YeastPathways_PYRIMID-RNTSYN-PWY
 de novo biosynthesis of pyrimidine ribonucleotides - imported from: Saccharomyces Genome Database 2026-07-14 Curators at SGD, Stacia Engel success 
YeastPathways_PANTOSYN2-PWY
 pantothenate and coenzyme A biosynthesis - imported from: Saccharomyces Genome Database 2026-07-14 Curators at SGD, Stacia Engel success 
YeastPathways_PERIPLASMA-NAD-DEGRADATION
 periplasmic NAD degradation - imported from: Saccharomyces Genome Database 2026-07-14 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-5962
 superpathway of fatty acid biosynthesis, saturated and unsaturated - imported from: Saccharomyces Genome Database 2026-07-14 Curators at SGD, Edith Wong, Stacia Engel success
25 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'oleoyl-CoA(4-) [CHEBI:57387] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'palmitoyl hydrolase activity [GO:0098599] (molecular_function)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'coenzyme A(4-) [CHEBI:57287] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ coenzyme A(4-) [CHEBI:57287] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —part of→ fatty acid biosynthetic process [GO:0006633] (biological_process)
  • SKIPPED_FACT: Subject 'palmitoyl hydrolase activity [GO:0098599] (molecular_function)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —has output→ coenzyme A(4-) [CHEBI:57287] (chemical entity)
  • SKIPPED_FACT: Subject 'palmitoyl hydrolase activity [GO:0098599] (molecular_function)' has 'has input' relationship to 'palmitoyl-CoA(4-) [CHEBI:57379] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —has input→ palmitoyl-CoA(4-) [CHEBI:57379] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —has output→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'palmitoyl hydrolase activity [GO:0098599] (molecular_function)' has 'has output' relationship to 'hexadecanoate [CHEBI:7896] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'palmitoyl hydrolase activity [GO:0098599] (molecular_function)' has 'has output' relationship to 'coenzyme A(4-) [CHEBI:57287] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —has output→ hexadecanoate [CHEBI:7896] (chemical entity)
  • INDIVIDUAL_HAS_MULTIPLE_TYPES: Individual has multiple types; using the first type for translation
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ fatty acid biosynthetic process [GO:0006633] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ water [CHEBI:15377] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: palmitoyl hydrolase activity [GO:0098599] (molecular_function) —has input→ water [CHEBI:15377] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ oleate [CHEBI:30823] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ oleoyl-CoA(4-) [CHEBI:57387] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'oleate [CHEBI:30823] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_GLUCFERMEN-PWY
 superpathway of glucose fermentation - imported from: Saccharomyces Genome Database 2026-07-14 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-351
 superpathway of methionine salvage pathway - imported from: Saccharomyces Genome Database 2026-07-14 Curators at SGD, Rob Nash, Stacia Engel success 
YeastPathways_PWY-821-1
 superpathway of sulfur amino acid biosynthesis (<i>Saccharomyces cerevisiae</i>) - imported from: Saccharomyces Genome Database 2026-07-14 Curators at SGD, Stacia Engel success 
YeastPathways_P4-PWY-1
 superpathway of threonine and methionine biosynthesis - imported from: Saccharomyces Genome Database 2026-07-14 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-64
 methionine salvage pathway - imported from: Saccharomyces Genome Database 2026-07-13 Curators at SGD, Stacia Engel success 
YeastPathways_NADSYN-PWY
 NAD <i>de novo</i> biosynthesis II (from tryptophan) - imported from: Saccharomyces Genome Database 2026-07-13 Curators at SGD, Stacia Engel success
8 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'quinolinate(2-) [CHEBI:29959] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate [CHEBI:994] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ NAD+ biosynthetic process [GO:0009435] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ quinolinate(2-) [CHEBI:29959] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate [CHEBI:994] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_PWY3O-4107
 NAD salvage pathway V (PNC V cycle) - imported from: Saccharomyces Genome Database 2026-07-13 Curators at SGD, Stacia Engel success 
YeastPathways_NONOXIPENT-PWY
 pentose phosphate pathway (non-oxidative branch) - imported from: Saccharomyces Genome Database 2026-07-13 Curators at SGD, Stacia Engel success 
YeastPathways_OXIDATIVEPENT-PWY
 pentose phosphate pathway (oxidative branch) I - imported from: Saccharomyces Genome Database 2026-07-13 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-6499
 phosphatidate biosynthesis II (the glycerol-3-phosphate pathway) - imported from: Saccharomyces Genome Database 2026-07-13 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-355
 stearate biosynthesis III (fungi) - imported from: Saccharomyces Genome Database 2026-07-13 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-6126-1
 superpathway of adenosine nucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database 2026-07-13 Curators at SGD, Stacia Engel success
14 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'dATP(4-) [CHEBI:61404] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ formate [CHEBI:15740] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'carbon dioxide [CHEBI:16526] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'ATP(4-) [CHEBI:30616] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ carbon dioxide [CHEBI:16526] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'formate [CHEBI:15740] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ adenosine biosynthetic process [GO:0046086] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ ATP(4-) [CHEBI:30616] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ dATP(4-) [CHEBI:61404] (chemical entity) 
YeastPathways_COMPLETE-ARO-PWY-1
 superpathway of aromatic amino acid biosynthesis - imported from: Saccharomyces Genome Database 2026-07-13 Curators at SGD, Rob Nash, Stacia Engel success 
YeastPathways_ERGOSTEROL-SYN-PWY-1
 superpathway of ergosterol biosynthesis I - imported from: Saccharomyces Genome Database 2026-07-13 Curators at SGD, Rob Nash, Stacia Engel success 
YeastPathways_LEUSYN-PWY-1
 L-leucine biosynthesis - imported from: Saccharomyces Genome Database 2026-07-10 Curators at SGD, Stacia Engel success 
YeastPathways_LYSINE-AMINOAD-PWY-2
 L-lysine biosynthesis IV - imported from: Saccharomyces Genome Database 2026-07-10 Curators at SGD, Stacia Engel success 
YeastPathways_SERSYN-PWY
 L-serine biosynthesis I - imported from: Saccharomyces Genome Database 2026-07-10 Curators at SGD, Rob Nash, Stacia Engel success 
YeastPathways_TRYPTOPHAN-DEGRADATION-1
 L-tryptophan degradation III (eukaryotic) - imported from: Saccharomyces Genome Database 2026-07-10 Curators at SGD, Stacia Engel success
8 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ quinolinic acid [CHEBI:16675] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'quinolinic acid [CHEBI:16675] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ L-tryptophan catabolic process [GO:0006569] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate [CHEBI:994] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate [CHEBI:994] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_PWY-5651
 L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde - imported from: Saccharomyces Genome Database 2026-07-10 Curators at SGD, Stacia Engel success 
YeastPathways_VALSYN-PWY
 L-valine biosynthesis - imported from: Saccharomyces Genome Database 2026-07-10 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-4112
 leucine degradation - imported from: Saccharomyces Genome Database 2026-07-10 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-7219
 adenosine ribonucleotides <i>de novo</i> biosynthesis - imported from: Saccharomyces Genome Database 2026-07-08 Curators at SGD, Stacia Engel success 
YeastPathways_ARO-PWY-1
 chorismate biosynthesis - imported from: Saccharomyces Genome Database 2026-07-08 Curators at SGD, Stacia Engel success 
YeastPathways_YEAST-GALACT-METAB-PWY
 galactose degradation - imported from: Saccharomyces Genome Database 2026-07-08 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_GLYCOCAT-YEAST-PWY
 glycogen catabolism - imported from: Saccharomyces Genome Database 2026-07-08 Curators at SGD, David Hill, Stacia Engel filtered Model has at least one activity with no causal relations
2 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: amylo-alpha-1,6-glucosidase activity [GO:0004135] (molecular_function) —has input→ gomodel:aa92b0ae-395a-4869-9f49-815d75328b34_RXN-9023
  • MISSING_TERM: While processing 'amylo-alpha-1,6-glucosidase activity [GO:0004135] (molecular_function)' has input 'gomodel:aa92b0ae-395a-4869-9f49-815d75328b34_RXN-9023', the object could not be mapped to a term; skipping this fact. 
YeastPathways_PWY-7221
 guanosine ribonucleotides <i>de novo</i> biosynthesis - imported from: Saccharomyces Genome Database 2026-07-08 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-402
 inositol phosphate biosynthesis - imported from: Saccharomyces Genome Database 2026-07-08 Curators at SGD, Stacia Engel success
10 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'ADP(3-) [CHEBI:456216] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ ATP(4-) [CHEBI:30616] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'CHEBI:52965', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ ADP(3-) [CHEBI:456216] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ CHEBI:52965
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ inositol phosphate biosynthetic process [GO:0032958] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'ATP(4-) [CHEBI:30616] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'CHEBI:53064', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ CHEBI:53064 
YeastPathways_ARGSYNBSUB-PWY
 L-arginine biosynthesis II (acetyl cycle) - imported from: Saccharomyces Genome Database 2026-07-08 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_ILEUSYN-PWY-1
 L-isoleucine biosynthesis I (from threonine) - imported from: Saccharomyces Genome Database 2026-07-08 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-48
 glycerol biosynthesis - imported from: Saccharomyces Genome Database 2026-07-07 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-1743
 mannose degradation - imported from: Saccharomyces Genome Database 2026-07-07 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-5971-1
 myristate biosynthesis - imported from: Saccharomyces Genome Database 2026-07-07 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-5653
 NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde - imported from: Saccharomyces Genome Database 2026-07-07 Curators at SGD, Stacia Engel success
8 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ quinolinic acid [CHEBI:16675] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'quinolinic acid [CHEBI:16675] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate [CHEBI:994] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ NAD+ biosynthetic process [GO:0009435] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate [CHEBI:994] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_PWY3O-6407
 phosphatidate biosynthesis I (the dihydroxyacetone pathway) - imported from: Saccharomyces Genome Database 2026-07-07 Curators at SGD, Stacia Engel success 
YeastPathways_PYRUVDEHYD-PWY
 pyruvate decarboxylation to acetyl CoA - imported from: Saccharomyces Genome Database 2026-07-07 Curators at SGD, Stacia Engel, Suzi Aleksander success 
YeastPathways_DETOX1-PWY
 superoxide radicals degradation - imported from: Saccharomyces Genome Database 2026-07-07 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-5686-1
 UMP biosynthesis I - imported from: Saccharomyces Genome Database 2026-07-07 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-7176
 UTP and CTP <i>de novo</i> biosynthesis - imported from: Saccharomyces Genome Database 2026-07-07 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-5760-1
 beta-alanine biosynthesis IV - imported from: Saccharomyces Genome Database 2026-07-06 Curators at SGD, Stacia Engel success
1 warning
  • SKIPPED_FACT: 'aldehyde dehydrogenase (NAD+) activity [GO:0004029] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'beta-alanine biosynthetic process [GO:0019483] (biological_process)' 
YeastPathways_PWY3O-4
 carnitine shuttle - imported from: Saccharomyces Genome Database 2026-07-06 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-5177
 glutaryl-CoA degradation - imported from: Saccharomyces Genome Database 2026-07-06 Curators at SGD, Stacia Engel success
19 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ trans-4-carboxybut-2-enoyl-CoA(5-) [CHEBI:57353] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'information biomacromolecule [CHEBI:33695] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ information biomacromolecule [CHEBI:33695] (information biomacromolecule)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'trans-4-carboxybut-2-enoyl-CoA(5-) [CHEBI:57353] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ information biomacromolecule [CHEBI:33695] (information biomacromolecule)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'glutaryl-CoA(5-) [CHEBI:57378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ carbon dioxide [CHEBI:16526] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'information biomacromolecule [CHEBI:33695] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ carboxylic acid catabolic process [GO:0046395] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'carbon dioxide [CHEBI:16526] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'crotonoyl-CoA(4-) [CHEBI:57332] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ glutaryl-CoA(5-) [CHEBI:57378] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'trans-4-carboxybut-2-enoyl-CoA(5-) [CHEBI:57353] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ crotonoyl-CoA(4-) [CHEBI:57332] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ trans-4-carboxybut-2-enoyl-CoA(5-) [CHEBI:57353] (chemical entity) 
YeastPathways_PWY-901
 methylglyoxal catabolism - imported from: Saccharomyces Genome Database 2026-07-06 Curators at SGD, Rob Nash, Stacia Engel success 
YeastPathways_PWY3O-8514
 palmitate biosynthesis - imported from: Saccharomyces Genome Database 2026-07-06 Curators at SGD, Stacia Engel success
12 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'coenzyme A(4-) [CHEBI:57287] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'hexadecanoate [CHEBI:7896] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ coenzyme A(4-) [CHEBI:57287] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ palmitoyl-CoA(4-) [CHEBI:57379] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ fatty acid biosynthetic process [GO:0006633] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ hexadecanoate [CHEBI:7896] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'palmitoyl-CoA(4-) [CHEBI:57379] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_PWY-5669
 phosphatidylethanolamine biosynthesis I - imported from: Saccharomyces Genome Database 2026-07-06 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-440
 pyruvate fermentation to acetoin III - imported from: Saccharomyces Genome Database 2026-07-06 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-2301
 <i>myo</i>-inositol biosynthesis - imported from: Saccharomyces Genome Database 2026-07-02 Curators at SGD, Rob Nash, Stacia Engel success 
YeastPathways_PWY-5041
 <i>S</i>-adenosyl-L-methionine cycle II - imported from: Saccharomyces Genome Database 2026-07-02 Curators at SGD, Edith Wong, Stacia Engel success
12 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: S-methyltransferase activity [GO:0008172] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: S-methyltransferase activity [GO:0008172] (molecular_function) —has input→ R-H [CHEBI:142491] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: S-methyltransferase activity [GO:0008172] (molecular_function) —has output→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'S-methyltransferase activity [GO:0008172] (molecular_function)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: S-methyltransferase activity [GO:0008172] (molecular_function) —has output→ S-adenosyl-L-homocysteine zwitterion [CHEBI:57856] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: S-methyltransferase activity [GO:0008172] (molecular_function) —has output→ chemical entity [CHEBI:24431] (chemical entity)
  • SKIPPED_FACT: Subject 'S-methyltransferase activity [GO:0008172] (molecular_function)' has 'has output' relationship to 'S-adenosyl-L-homocysteine zwitterion [CHEBI:57856] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'S-methyltransferase activity [GO:0008172] (molecular_function)' has 'has input' relationship to 'S-adenosyl-L-methionine zwitterion [CHEBI:59789] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: S-methyltransferase activity [GO:0008172] (molecular_function) —part of→ L-methionine cycle [GO:0033353] (biological_process)
  • SKIPPED_FACT: Subject 'S-methyltransferase activity [GO:0008172] (molecular_function)' has 'has output' relationship to 'chemical entity [CHEBI:24431] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: S-methyltransferase activity [GO:0008172] (molecular_function) —has input→ S-adenosyl-L-methionine zwitterion [CHEBI:59789] (chemical entity)
  • SKIPPED_FACT: Subject 'S-methyltransferase activity [GO:0008172] (molecular_function)' has 'has input' relationship to 'R-H [CHEBI:142491] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_PWY-7220-1
 adenosine deoxyribonucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database 2026-07-02 Curators at SGD, Stacia Engel success
15 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'dATP(4-) [CHEBI:61404] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ adenosine metabolic process [GO:0046085] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'carbon dioxide [CHEBI:16526] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'ATP(4-) [CHEBI:30616] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ ATP(4-) [CHEBI:30616] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ dATP(4-) [CHEBI:61404] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'formate [CHEBI:15740] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ formate [CHEBI:15740] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: nucleoside diphosphate kinase activity [GO:0004550] (molecular_function) —causally upstream of→ Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ carbon dioxide [CHEBI:16526] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity) 
YeastPathways_PWY-5080-1
 very long chain fatty acid biosynthesis I - imported from: Saccharomyces Genome Database 2026-07-02 Curators at SGD, Stacia Engel success
2 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: very-long-chain enoyl-CoA reductase activity [GO:0102758] (molecular_function) —has input→ gomodel:46fed9f2-cf0b-4568-b40e-557bd0cfffe5_RXN3O-9813
  • MISSING_TERM: While processing 'very-long-chain enoyl-CoA reductase activity [GO:0102758] (molecular_function)' has input 'gomodel:46fed9f2-cf0b-4568-b40e-557bd0cfffe5_RXN3O-9813', the object could not be mapped to a term; skipping this fact. 
YeastPathways_YEAST-4AMINOBUTMETAB-PWY
 4-aminobutyrate degradation - imported from: Saccharomyces Genome Database 2026-04-22 Curators at SGD, Edith Wong, Rob Nash success 
66187e4700002129
 Feedback regulation of erythropoietin-mediated signaling via ubiquitination and degradation of EPOR by the ECS(SOCS2) complex (Human). 2026-03-12 Suzi Aleksander, Sylvain Poux success 
6348a65d00000394
 Gut Microbiota lactate metabolism: Improvement of glucose tolerance by induction of REG3G. (Mouse-Lactobacillus) 2026-03-12 Cristina Casals, David Hill, Suzi Aleksander success 
YeastPathways_GLUCOSE-MANNOSYL-CHITO-DOLICHOL
 lipid-linked oligosaccharide biosynthesis - imported from: Saccharomyces Genome Database 2026-03-03 Curators at SGD, Stacia Engel success
2 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: alpha-1,2-mannosyltransferase activity [GO:0000026] (molecular_function) —has input→ gomodel:f32dfb94-2ac8-4a24-9bd0-306aab2d4da8_RXN3O-379
  • MISSING_TERM: While processing 'alpha-1,2-mannosyltransferase activity [GO:0000026] (molecular_function)' has input 'gomodel:f32dfb94-2ac8-4a24-9bd0-306aab2d4da8_RXN3O-379', the object could not be mapped to a term; skipping this fact. 
6446bfcb00001774
 Autophagosome assembly (Human) 2026-02-15 Lucille Pourcel, Marc Feuermann, Suzi Aleksander, Sylvain Poux success 
680ad14200003035
 epinephrine biosynthetic process (rat) 2026-01-23 Shur-Jen Wang, Suzi Aleksander success 
YeastPathways_PWY3O-954
 superpathway of methionine biosynthesis - imported from: Saccharomyces Genome Database 2026-01-08 Curators at SGD, Stacia Engel success 
YeastPathways_ARGSPECAT-PWY
 spermine biosynthesis - imported from: Saccharomyces Genome Database 2025-12-11 Curators at SGD, Stacia Engel success 
626b20c100000443
 Regulation of gluconeogenesis by TOX4 (Mouse) 2025-12-08 Cristina Casals, David Hill, Suzi Aleksander success 
SGD_S000000103
 SLA1 (SGD:S000000103) 2025-06-13 Diane Inglis, GOC:Julie_Park, Jodi Hirschman, Kara Dolinski, Rob Nash, Stacia Engel, Terry L. Jackson filtered Model has at least one activity with no causal relations
7 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: SLA1 Scer [SGD:S000000103] (information biomacromolecule) —part of→ actin cytoskeleton-regulatory complex [GO:1990964] (cellular_component)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: SLA1 Scer [SGD:S000000103] (information biomacromolecule) —located in→ cellular bud neck [GO:0005935] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: SLA1 Scer [SGD:S000000103] (information biomacromolecule) —located in→ actin cortical patch [GO:0030479] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: SLA1 Scer [SGD:S000000103] (information biomacromolecule) —part of→ SLAC complex [GO:0140224] (cellular_component)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: SLA1 Scer [SGD:S000000103] (information biomacromolecule) —located in→ cell cortex [GO:0005938] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: SLA1 Scer [SGD:S000000103] (information biomacromolecule) —located in→ mating projection tip [GO:0043332] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: SLA1 Scer [SGD:S000000103] (information biomacromolecule) —located in→ nucleus [GO:0005634] (anatomical entity) 
63e5937500000106
 Activation of the GCN2-mediated signaling by GCN1 in response to ribosome collisions and inhibition of GCN2 by HEL2 (S.cerevisiae) 2025-05-02 Stacia Engel, Sylvain Poux success 
YeastPathways_PWY3O-94
 superpathway of TCA cycle and glyoxylate cycle - imported from: Saccharomyces Genome Database 2025-04-24 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations
1 warning
  • MULTIPLE_ACTIVITIES: Multiple activities for object aconitate hydratase activity [GO:0003994] (molecular_function) 
YeastPathways_PWY3O-285
 superpathway of purine biosynthesis and salvage pathways - imported from: Saccharomyces Genome Database 2025-03-27 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations
24 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'dGTP(4-) [CHEBI:61429] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'carbon dioxide [CHEBI:16526] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'ATP(4-) [CHEBI:30616] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'GTP(4-) [CHEBI:37565] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ carbon dioxide [CHEBI:16526] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ dGTP(4-) [CHEBI:61429] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ dATP(4-) [CHEBI:61404] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —causally upstream of→ nucleoside diphosphate kinase activity [GO:0004550] (molecular_function)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ purine-containing compound salvage [GO:0043101] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'formate [CHEBI:15740] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • MULTIPLE_ACTIVITIES: Multiple activities for subject adenine phosphoribosyltransferase activity [GO:0003999] (molecular_function)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'dATP(4-) [CHEBI:61404] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'carbon dioxide [CHEBI:16526] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ formate [CHEBI:15740] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ ATP(4-) [CHEBI:30616] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'formate [CHEBI:15740] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ GTP(4-) [CHEBI:37565] (chemical entity) 
YeastPathways_PWY3O-5268
 oleate biosynthesis - imported from: Saccharomyces Genome Database 2025-03-04 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-5694
 allantoin degradation to glyoxylate I - imported from: Saccharomyces Genome Database 2025-02-19 Curators at SGD, Stacia Engel success 
613aae0000000885
 PTPRM role in glucose transport activity through inhibition of CTNND1 (Human) 2025-01-08 Patrick Masson, Suzi Aleksander success 
66a3e0bb00002971
 SETDB1 activation through monoubiquitination by UBE2E3. (Human) 2024-12-03 Cristina Casals, Suzi Aleksander success 
YeastPathways_PWY-5670-1
 epoxysqualene biosynthesis - imported from: Saccharomyces Genome Database 2024-09-12 Curators at SGD, Edith Wong, Stacia Engel success 
YeastPathways_PWY3O-31704
 ergosterol biosynthesis - imported from: Saccharomyces Genome Database 2024-09-12 Curators at SGD, Edith Wong success 
YeastPathways_PWY-6074-1
 zymosterol biosynthesis - imported from: Saccharomyces Genome Database 2024-09-12 Curators at SGD, Stacia Engel success 
YeastPathways_ALL-CHORISMATE-PWY-1
 superpathway of chorismate metabolism - imported from: Saccharomyces Genome Database 2024-08-09 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations
32 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: glycine hydroxymethyltransferase activity [GO:0004372] (molecular_function) —has input→ gomodel:b8f308ae-dd25-4b12-a6d0-2874aac08cf6_DIHYDROFOLATEREDUCT-RXN
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ hydrogenphosphate [CHEBI:43474] (chemical entity)
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • MULTIPLE_ACTIVITIES: Multiple activities for object formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function)
  • MULTIPLE_ACTIVITIES: Multiple activities for object glycine hydroxymethyltransferase activity [GO:0004372] (molecular_function)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has output→ diphosphoric acid [CHEBI:29888] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '7,8-dihydroneopterin [CHEBI:17001] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has input' relationship to '7,8-dihydroneopterin 3'-triphosphate(4-) [CHEBI:58462] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • MISSING_TERM: While processing 'glycine hydroxymethyltransferase activity [GO:0004372] (molecular_function)' has input 'gomodel:b8f308ae-dd25-4b12-a6d0-2874aac08cf6_DIHYDROFOLATEREDUCT-RXN', the object could not be mapped to a term; skipping this fact.
  • MULTIPLE_ACTIVITIES: Multiple activities for subject methenyltetrahydrofolate cyclohydrolase activity [GO:0004477] (molecular_function)
  • MISSING_TERM: While processing 'formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function)' has input 'gomodel:817d74f2-6872-497c-84a3-889589db4f00_1.5.1.15-RXN', the object could not be mapped to a term; skipping this fact.
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has output→ 7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'hydrogenphosphate [CHEBI:43474] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function) —has input→ gomodel:817d74f2-6872-497c-84a3-889589db4f00_1.5.1.15-RXN
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has output' relationship to '7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has input→ 7,8-dihydroneopterin 3'-triphosphate(4-) [CHEBI:58462] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ chorismate metabolic process [GO:0046417] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has output→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —part of→ chorismate metabolic process [GO:0046417] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • MISSING_TERM: While processing 'formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function)' has input 'gomodel:fc349edc-88e4-4bc3-8a2c-80fc9eccc8c9_DIHYDROFOLATEREDUCT-RXN', the object could not be mapped to a term; skipping this fact.
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has output' relationship to 'diphosphoric acid [CHEBI:29888] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • MULTIPLE_ACTIVITIES: Multiple activities for object formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ 7,8-dihydroneopterin [CHEBI:17001] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function) —has input→ gomodel:fc349edc-88e4-4bc3-8a2c-80fc9eccc8c9_DIHYDROFOLATEREDUCT-RXN 
YeastPathways_PRPP-PWY-1
 superpathway of histidine, purine, and pyrimidine biosynthesis - imported from: Saccharomyces Genome Database 2024-08-09 Curators at SGD, Stacia Engel success
22 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'dGTP(4-) [CHEBI:61429] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'carbon dioxide [CHEBI:16526] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'ATP(4-) [CHEBI:30616] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ dATP(4-) [CHEBI:61404] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'GTP(4-) [CHEBI:37565] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'formate [CHEBI:15740] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ nucleotide biosynthetic process [GO:0009165] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'dATP(4-) [CHEBI:61404] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ ATP(4-) [CHEBI:30616] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'carbon dioxide [CHEBI:16526] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ formate [CHEBI:15740] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ GTP(4-) [CHEBI:37565] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ carbon dioxide [CHEBI:16526] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'formate [CHEBI:15740] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ dGTP(4-) [CHEBI:61429] (chemical entity) 
YeastPathways_FOLSYN-PWY-1
 superpathway of tetrahydrofolate biosynthesis and salvage - imported from: Saccharomyces Genome Database 2024-08-09 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations
32 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ 7,8-dihydroneopterin [CHEBI:17001] (chemical entity)
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • MULTIPLE_ACTIVITIES: Multiple activities for object formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ folate cycle [GO:0035999] (biological_process)
  • MULTIPLE_ACTIVITIES: Multiple activities for object glycine hydroxymethyltransferase activity [GO:0004372] (molecular_function)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ hydrogenphosphate [CHEBI:43474] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '7,8-dihydroneopterin [CHEBI:17001] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has input' relationship to '7,8-dihydroneopterin 3'-triphosphate(4-) [CHEBI:58462] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • MISSING_TERM: While processing 'formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function)' has input 'gomodel:793b998d-9e9d-44c2-927c-6dc08283429b_1.5.1.15-RXN', the object could not be mapped to a term; skipping this fact.
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —part of→ folate cycle [GO:0035999] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has output→ diphosphoric acid [CHEBI:29888] (chemical entity)
  • MULTIPLE_ACTIVITIES: Multiple activities for subject methenyltetrahydrofolate cyclohydrolase activity [GO:0004477] (molecular_function)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has input→ water [CHEBI:15377] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function) —has input→ gomodel:793b998d-9e9d-44c2-927c-6dc08283429b_1.5.1.15-RXN
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'hydrogenphosphate [CHEBI:43474] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has output' relationship to '7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: glycine hydroxymethyltransferase activity [GO:0004372] (molecular_function) —has input→ gomodel:05a5decb-73b4-4ddd-a7bd-89cd301f566a_DIHYDROFOLATEREDUCT-RXN
  • MISSING_TERM: While processing 'glycine hydroxymethyltransferase activity [GO:0004372] (molecular_function)' has input 'gomodel:05a5decb-73b4-4ddd-a7bd-89cd301f566a_DIHYDROFOLATEREDUCT-RXN', the object could not be mapped to a term; skipping this fact.
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has output→ 7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has output' relationship to 'diphosphoric acid [CHEBI:29888] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • MULTIPLE_ACTIVITIES: Multiple activities for object formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has input→ 7,8-dihydroneopterin 3'-triphosphate(4-) [CHEBI:58462] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has output→ hydron [CHEBI:15378] (chemical entity)
  • MISSING_TERM: While processing 'formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function)' has input 'gomodel:b0c18b2c-4abb-41e9-8842-0422d4e55ae5_DIHYDROFOLATEREDUCT-RXN', the object could not be mapped to a term; skipping this fact.
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ water [CHEBI:15377] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: formate-tetrahydrofolate ligase activity [GO:0004329] (molecular_function) —has input→ gomodel:b0c18b2c-4abb-41e9-8842-0422d4e55ae5_DIHYDROFOLATEREDUCT-RXN 
YeastPathways_PWY3O-4120
 tyrosine biosynthesis - imported from: Saccharomyces Genome Database 2024-08-09 Curators at SGD, Rob Nash, Stacia Engel success 
YeastPathways_PWY3O-4153
 phenylalanine biosynthesis - imported from: Saccharomyces Genome Database 2024-08-08 Curators at SGD, Rob Nash, Stacia Engel success 
YeastPathways_PWY3O-2
 superpathway of phospholipid biosynthesis - imported from: Saccharomyces Genome Database 2024-08-01 Curators at SGD, Edith Wong filtered Model has at least one activity with no causal relations
10 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: phosphatidylglycerophosphatase activity [GO:0008962] (molecular_function) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'phosphatidylglycerophosphatase activity [GO:0008962] (molecular_function)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: phosphatidylglycerophosphatase activity [GO:0008962] (molecular_function) —has input→ 1-(3-sn-phosphatidyl)-sn-glycerol 3-phosphate [CHEBI:37393] (chemical entity)
  • SKIPPED_FACT: Subject 'phosphatidylglycerophosphatase activity [GO:0008962] (molecular_function)' has 'has output' relationship to 'hydrogenphosphate [CHEBI:43474] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: phosphatidylglycerophosphatase activity [GO:0008962] (molecular_function) —part of→ phospholipid biosynthetic process [GO:0008654] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: phosphatidylglycerophosphatase activity [GO:0008962] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: phosphatidylglycerophosphatase activity [GO:0008962] (molecular_function) —has output→ 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) [CHEBI:64716] (chemical entity)
  • SKIPPED_FACT: Subject 'phosphatidylglycerophosphatase activity [GO:0008962] (molecular_function)' has 'has output' relationship to '1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) [CHEBI:64716] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'phosphatidylglycerophosphatase activity [GO:0008962] (molecular_function)' has 'has input' relationship to '1-(3-sn-phosphatidyl)-sn-glycerol 3-phosphate [CHEBI:37393] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: phosphatidylglycerophosphatase activity [GO:0008962] (molecular_function) —has output→ hydrogenphosphate [CHEBI:43474] (chemical entity) 
SGD_S000001584
 HSL1 (SGD:S000001584) 2024-07-31 Chandra Theesfeld, GOC:Julie_Park, Kara Dolinski, Rama Balakrishnan, Rob Nash filtered Model has at least one activity with no causal relations
6 warnings
  • SKIPPED_FACT: Subject 'protein catabolic process [GO:0030163] (biological_process)' has 'has input' relationship to 'SWE1 Scer [SGD:S000003723] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: HSL1 Scer [SGD:S000001584] (information biomacromolecule) —located in→ cellular bud neck [GO:0005935] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: protein catabolic process [GO:0030163] (biological_process) —has input→ SWE1 Scer [SGD:S000003723] (information biomacromolecule)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: protein localization to septin ring [GO:1902935] (biological_process) —has input→ HSL7 Scer [SGD:S000000337] (information biomacromolecule)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: HSL1 Scer [SGD:S000001584] (information biomacromolecule) —located in→ cellular bud neck septin ring [GO:0000144] (anatomical entity)
  • SKIPPED_FACT: Subject 'protein localization to septin ring [GO:1902935] (biological_process)' has 'has input' relationship to 'HSL7 Scer [SGD:S000000337] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association 
YeastPathways_YEAST-DE-NOVO-PYRMID-DNT
 de novo biosynthesis of pyrimidine deoxyribonucleotides - imported from: Saccharomyces Genome Database 2024-07-30 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations
12 warnings
  • SKIPPED_FACT: Subject 'dCTP deaminase activity [GO:0008829] (molecular_function)' has 'has output' relationship to 'ammonium [CHEBI:28938] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'dCTP deaminase activity [GO:0008829] (molecular_function)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dCTP deaminase activity [GO:0008829] (molecular_function) —part of→ 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dCTP deaminase activity [GO:0008829] (molecular_function) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'dCTP deaminase activity [GO:0008829] (molecular_function)' has 'has output' relationship to 'dUTP(4-) [CHEBI:61555] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'dCTP deaminase activity [GO:0008829] (molecular_function)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dCTP deaminase activity [GO:0008829] (molecular_function) —has input→ dCTP(4-) [CHEBI:61481] (chemical entity)
  • SKIPPED_FACT: Subject 'dCTP deaminase activity [GO:0008829] (molecular_function)' has 'has input' relationship to 'dCTP(4-) [CHEBI:61481] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dCTP deaminase activity [GO:0008829] (molecular_function) —has output→ ammonium [CHEBI:28938] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dCTP deaminase activity [GO:0008829] (molecular_function) —has input→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dCTP deaminase activity [GO:0008829] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dCTP deaminase activity [GO:0008829] (molecular_function) —has output→ dUTP(4-) [CHEBI:61555] (chemical entity) 
YeastPathways_THREOCAT2-PWY
 threonine degradation - imported from: Saccharomyces Genome Database 2024-07-30 Curators at SGD, Stacia Engel success
96 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ propanoyl phosphate(2-) [CHEBI:58933] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'methylglyoxal [CHEBI:17158] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function) —has input→ NAD(1-) [CHEBI:57540] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'propanoyl phosphate(2-) [CHEBI:58933] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function) —part of→ L-threonine catabolic process [GO:0006567] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'propionyl-CoA(4-) [CHEBI:57392] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject '(R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function)' has 'has input' relationship to 'ammonioacetone [CHEBI:58320] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: (R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'coenzyme A(4-) [CHEBI:57287] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ ammonioacetone [CHEBI:58320] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ ammonium [CHEBI:28938] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: glycine C-acetyltransferase activity [GO:0008890] (molecular_function) —has output→ acetyl-CoA(4-) [CHEBI:57288] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'formate [CHEBI:15740] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'coenzyme A(4-) [CHEBI:57287] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'L-2-amino-3-oxobutanoic acid zwitterion [CHEBI:78948] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'dioxygen [CHEBI:15379] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ L-2-amino-3-oxobutanoic acid zwitterion [CHEBI:78948] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ coenzyme A(4-) [CHEBI:57287] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'ammonioacetone [CHEBI:58320] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'ammonioacetone [CHEBI:58320] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'glycine C-acetyltransferase activity [GO:0008890] (molecular_function)' has 'has input' relationship to 'coenzyme A(4-) [CHEBI:57287] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ ammonium [CHEBI:28938] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ propionyl-CoA(4-) [CHEBI:57392] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: glycine C-acetyltransferase activity [GO:0008890] (molecular_function) —has input→ coenzyme A(4-) [CHEBI:57287] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydrogenphosphate [CHEBI:43474] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 2-oxobutanoate [CHEBI:16763] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: propionate kinase activity [GO:0008980] (molecular_function) —has output→ propionate [CHEBI:17272] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: (R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function) —part of→ L-threonine catabolic process [GO:0006567] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: propionate kinase activity [GO:0008980] (molecular_function) —has input→ ADP(3-) [CHEBI:456216] (chemical entity)
  • SKIPPED_FACT: Subject 'glycine C-acetyltransferase activity [GO:0008890] (molecular_function)' has 'has output' relationship to 'acetyl-CoA(4-) [CHEBI:57288] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydrogenphosphate [CHEBI:43474] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'O-succinyl-L-homoserinate(1-) [CHEBI:57661] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ L-threonine catabolic process [GO:0006567] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: glycine C-acetyltransferase activity [GO:0008890] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ coenzyme A(4-) [CHEBI:57287] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '2-oxobutanoate [CHEBI:16763] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: (R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function) —has input→ ammonioacetone [CHEBI:58320] (chemical entity)
  • SKIPPED_FACT: Subject 'propionate kinase activity [GO:0008980] (molecular_function)' has 'has output' relationship to 'propionate [CHEBI:17272] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ hydrogen peroxide [CHEBI:16240] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ L-homoserine zwitterion [CHEBI:57476] (chemical entity)
  • SKIPPED_FACT: Subject 'propionate kinase activity [GO:0008980] (molecular_function)' has 'has output' relationship to 'ATP(4-) [CHEBI:30616] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: propionate kinase activity [GO:0008980] (molecular_function) —part of→ L-threonine catabolic process [GO:0006567] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: propionate kinase activity [GO:0008980] (molecular_function) —has input→ propanoyl phosphate(2-) [CHEBI:58933] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '2-oxobutanoate [CHEBI:16763] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject '(R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function)' has 'has input' relationship to 'NADH(2-) [CHEBI:57945] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'ammonium [CHEBI:28938] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'hydrogen peroxide [CHEBI:16240] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: (R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function) —has input→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'ammonium [CHEBI:28938] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function) —has output→ NADH(2-) [CHEBI:57945] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function) —has input→ L-threonine zwitterion [CHEBI:57926] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'succinate(2-) [CHEBI:30031] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: glycine C-acetyltransferase activity [GO:0008890] (molecular_function) —has output→ glycine zwitterion [CHEBI:57305] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: glycine C-acetyltransferase activity [GO:0008890] (molecular_function) —has input→ L-2-amino-3-oxobutanoic acid zwitterion [CHEBI:78948] (chemical entity)
  • SKIPPED_FACT: Subject 'L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'L-homoserine zwitterion [CHEBI:57476] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: (R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function) —has output→ (2R)-2-hydroxypropylammonium [CHEBI:42677] (chemical entity)
  • SKIPPED_FACT: Subject 'propionate kinase activity [GO:0008980] (molecular_function)' has 'has input' relationship to 'ADP(3-) [CHEBI:456216] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: propionate kinase activity [GO:0008980] (molecular_function) —has output→ ATP(4-) [CHEBI:30616] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function) —has output→ L-2-amino-3-oxobutanoic acid zwitterion [CHEBI:78948] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'ammonium [CHEBI:28938] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ carbon dioxide [CHEBI:16526] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ dioxygen [CHEBI:15379] (chemical entity)
  • SKIPPED_FACT: Subject 'glycine C-acetyltransferase activity [GO:0008890] (molecular_function)' has 'has input' relationship to 'L-2-amino-3-oxobutanoic acid zwitterion [CHEBI:78948] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject '(R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject '(R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function)' has 'has output' relationship to '(2R)-2-hydroxypropylammonium [CHEBI:42677] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject '(R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function)' has 'has output' relationship to 'NAD(1-) [CHEBI:57540] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'glycine C-acetyltransferase activity [GO:0008890] (molecular_function)' has 'has output' relationship to 'glycine zwitterion [CHEBI:57305] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: (R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function) —has input→ NADH(2-) [CHEBI:57945] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: propionate kinase activity [GO:0008980] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function)' has 'has output' relationship to 'NADH(2-) [CHEBI:57945] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function)' has 'has input' relationship to 'NAD(1-) [CHEBI:57540] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'carbon dioxide [CHEBI:16526] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ methylglyoxal [CHEBI:17158] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ O-succinyl-L-homoserinate(1-) [CHEBI:57661] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'propionate kinase activity [GO:0008980] (molecular_function)' has 'has input' relationship to 'propanoyl phosphate(2-) [CHEBI:58933] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'propionyl-CoA(4-) [CHEBI:57392] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ ammonioacetone [CHEBI:58320] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: (R)-aminopropanol dehydrogenase activity [GO:0019147] (molecular_function) —has output→ NAD(1-) [CHEBI:57540] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: glycine C-acetyltransferase activity [GO:0008890] (molecular_function) —part of→ L-threonine catabolic process [GO:0006567] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '2-oxobutanoate [CHEBI:16763] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function) —has output→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function)' has 'has input' relationship to 'L-threonine zwitterion [CHEBI:57926] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ formate [CHEBI:15740] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ succinate(2-) [CHEBI:30031] (chemical entity)
  • SKIPPED_FACT: Subject 'L-threonine 3-dehydrogenase activity [GO:0008743] (molecular_function)' has 'has output' relationship to 'L-2-amino-3-oxobutanoic acid zwitterion [CHEBI:78948] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ propionyl-CoA(4-) [CHEBI:57392] (chemical entity) 
YeastPathways_GLUDEG-I-PWY-1
 glutamate degradation I - imported from: Saccharomyces Genome Database 2024-07-25 Curators at SGD, Edith Wong success 
YeastPathways_HOMOCYS-CYS-CONVERT
 homocysteine and cysteine interconversion - imported from: Saccharomyces Genome Database 2024-07-25 Curators at SGD, Edith Wong success 
YeastPathways_PWY3O-981
 superpathway of acetoin and butanediol biosynthesis - imported from: Saccharomyces Genome Database 2024-07-22 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations
16 warnings
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'electron acceptor [CHEBI:17654] (role)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ butane-2,3-dione [CHEBI:16583] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ (2S)-2-hydroxy-2-methyl-3-oxobutanoate [CHEBI:58476] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'butane-2,3-dione [CHEBI:16583] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • MULTIPLE_ACTIVITIES: Multiple activities for subject pyruvate decarboxylase activity [GO:0004737] (molecular_function)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '(2S)-2-hydroxy-2-methyl-3-oxobutanoate [CHEBI:58476] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'electron acceptor [CHEBI:17654] (role)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ electron acceptor [CHEBI:17654] (role)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'carbon dioxide [CHEBI:16526] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ secondary alcohol metabolic process [GO:1902652] (biological_process)
  • MULTIPLE_ACTIVITIES: Multiple activities for subject pyruvate decarboxylase activity [GO:0004737] (molecular_function)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ carbon dioxide [CHEBI:16526] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ electron acceptor [CHEBI:17654] (role) 
YeastPathways_TCA-EUK-PWY
 TCA cycle, aerobic respiration - imported from: Saccharomyces Genome Database 2024-07-22 Curators at SGD, Edith Wong filtered Model has at least one activity with no causal relations
3 warnings
  • MULTIPLE_ACTIVITIES: Multiple activities for object succinate dehydrogenase (quinone) activity [GO:0008177] (molecular_function)
  • MULTIPLE_ACTIVITIES: Multiple activities for subject succinate dehydrogenase (quinone) activity [GO:0008177] (molecular_function)
  • MULTIPLE_ACTIVITIES: Multiple activities for object aconitate hydratase activity [GO:0003994] (molecular_function) 
YeastPathways_PWY-7222-1
 guanosine deoxyribonucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database 2024-07-19 Curators at SGD, Edith Wong filtered Model has at least one activity with no causal relations
1 warning
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: nucleoside diphosphate kinase activity [GO:0004550] (molecular_function) —causally upstream of→ Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) 
YeastPathways_PWY-5084
 2-oxoglutarate decarboxylation to succinyl-CoA - imported from: Saccharomyces Genome Database 2024-07-18 Curators at SGD, Stacia Engel success 
YeastPathways_PWY-6482-1
 diphthamide biosynthesis - imported from: Saccharomyces Genome Database 2024-07-18 Curators at SGD, Edith Wong success 
YeastPathways_PWY3O-862
 superpathway of ubiquinone biosynthesis - imported from: Saccharomyces Genome Database 2024-07-18 Curators at SGD, Stacia Engel success
85 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: chorismate lyase activity [GO:0008813] (molecular_function) —part of→ ubiquinone biosynthetic process [GO:0006744] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '(R)-3-(4-hydroxyphenyl)lactate [CHEBI:10980] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 3-hexaprenyl-4-hydroxy-5-methoxybenzoate [CHEBI:57916] (chemical entity)
  • SKIPPED_FACT: Subject 'geranylfarnesyl diphosphate synthase activity [GO:0044687] (molecular_function)' has 'has input' relationship to '2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) [CHEBI:58756] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: chorismate lyase activity [GO:0008813] (molecular_function) —has output→ pyruvate [CHEBI:15361] (chemical entity)
  • SKIPPED_FACT: Subject '4-coumarate-CoA ligase activity [GO:0016207] (molecular_function)' has 'has output' relationship to 'adenosine 5'-monophosphate(2-) [CHEBI:456215] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '3-(4-hydroxyphenyl)pyruvate [CHEBI:36242] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '4-coumaroyl-CoA [CHEBI:15499] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: geranylfarnesyl diphosphate synthase activity [GO:0044687] (molecular_function) —has output→ diphosphoric acid [CHEBI:29888] (chemical entity)
  • SKIPPED_FACT: Subject 'geranylfarnesyl diphosphate synthase activity [GO:0044687] (molecular_function)' has 'has output' relationship to 'diphosphoric acid [CHEBI:29888] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '3-(4-hydroxyphenyl)pyruvate [CHEBI:36242] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ NAD(1-) [CHEBI:57540] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '2-hexaprenyl-6-methoxyphenol [CHEBI:1109] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ (R)-3-(4-hydroxyphenyl)lactate [CHEBI:10980] (chemical entity)
  • SKIPPED_FACT: Subject 'geranylfarnesyl diphosphate synthase activity [GO:0044687] (molecular_function)' has 'has output' relationship to 'all-trans-pentaprenyl diphosphate(3-) [CHEBI:57907] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ carbon dioxide [CHEBI:16526] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '(R)-3-(4-hydroxyphenyl)lactate [CHEBI:10980] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ NAD(1-) [CHEBI:57540] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ NADH(2-) [CHEBI:57945] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: geranylfarnesyl diphosphate synthase activity [GO:0044687] (molecular_function) —has output→ all-trans-pentaprenyl diphosphate(3-) [CHEBI:57907] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: geranylfarnesyl diphosphate synthase activity [GO:0044687] (molecular_function) —has input→ isopentenyl diphosphate(3-) [CHEBI:128769] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: chorismate lyase activity [GO:0008813] (molecular_function) —has input→ chorismate(2-) [CHEBI:29748] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: chorismate lyase activity [GO:0008813] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ acetyl-CoA(4-) [CHEBI:57288] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject '4-coumarate-CoA ligase activity [GO:0016207] (molecular_function)' has 'has input' relationship to 'trans-4-coumarate [CHEBI:12876] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: 4-coumarate-CoA ligase activity [GO:0016207] (molecular_function) —part of→ ubiquinone biosynthetic process [GO:0006744] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ ammonia [CHEBI:16134] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: chorismate lyase activity [GO:0008813] (molecular_function) —has output→ 4-hydroxybenzoic acid [CHEBI:30763] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ L-tyrosine zwitterion [CHEBI:58315] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'L-tyrosine zwitterion [CHEBI:58315] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ 3-(4-hydroxyphenyl)pyruvate [CHEBI:36242] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: 4-coumarate-CoA ligase activity [GO:0016207] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ acetyl-CoA(4-) [CHEBI:57288] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: 4-coumarate-CoA ligase activity [GO:0016207] (molecular_function) —has output→ 4-coumaroyl-CoA [CHEBI:15499] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: 4-coumarate-CoA ligase activity [GO:0016207] (molecular_function) —has input→ trans-4-coumarate [CHEBI:12876] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ 2-hexaprenyl-6-methoxyphenol [CHEBI:1109] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ (R)-3-(4-hydroxyphenyl)lactate [CHEBI:10980] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: 4-coumarate-CoA ligase activity [GO:0016207] (molecular_function) —has input→ ATP(4-) [CHEBI:30616] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'trans-4-coumarate [CHEBI:12876] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ 4-hydroxybenzoyl-CoA(4-) [CHEBI:57356] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ hydron [CHEBI:15378] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'carbon dioxide [CHEBI:16526] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: geranylfarnesyl diphosphate synthase activity [GO:0044687] (molecular_function) —has input→ 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) [CHEBI:58756] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '4-hydroxybenzoic acid [CHEBI:30763] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject '4-coumarate-CoA ligase activity [GO:0016207] (molecular_function)' has 'has output' relationship to 'diphosphoric acid [CHEBI:29888] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'chorismate lyase activity [GO:0008813] (molecular_function)' has 'has input' relationship to 'chorismate(2-) [CHEBI:29748] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'NADH(2-) [CHEBI:57945] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '3-hexaprenyl-4-hydroxy-5-methoxybenzoate [CHEBI:57916] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 4-hydroxybenzoyl-CoA(4-) [CHEBI:57356] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'coenzyme A(4-) [CHEBI:57287] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: 4-coumarate-CoA ligase activity [GO:0016207] (molecular_function) —has output→ diphosphoric acid [CHEBI:29888] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 3-(4-hydroxyphenyl)pyruvate [CHEBI:36242] (chemical entity)
  • SKIPPED_FACT: Subject '4-coumarate-CoA ligase activity [GO:0016207] (molecular_function)' has 'has input' relationship to 'ATP(4-) [CHEBI:30616] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 4-coumaroyl-CoA [CHEBI:15499] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '4-hydroxybenzoyl-CoA(4-) [CHEBI:57356] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: 4-coumarate-CoA ligase activity [GO:0016207] (molecular_function) —has output→ adenosine 5'-monophosphate(2-) [CHEBI:456215] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ 4-hydroxybenzoic acid [CHEBI:30763] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ NADH(2-) [CHEBI:57945] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: geranylfarnesyl diphosphate synthase activity [GO:0044687] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'NADH(2-) [CHEBI:57945] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '4-hydroxybenzoyl-CoA(4-) [CHEBI:57356] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'ammonia [CHEBI:16134] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ coenzyme A(4-) [CHEBI:57287] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'acetyl-CoA(4-) [CHEBI:57288] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'NAD(1-) [CHEBI:57540] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'chorismate lyase activity [GO:0008813] (molecular_function)' has 'has output' relationship to '4-hydroxybenzoic acid [CHEBI:30763] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject '4-coumarate-CoA ligase activity [GO:0016207] (molecular_function)' has 'has output' relationship to '4-coumaroyl-CoA [CHEBI:15499] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'geranylfarnesyl diphosphate synthase activity [GO:0044687] (molecular_function)' has 'has input' relationship to 'isopentenyl diphosphate(3-) [CHEBI:128769] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'chorismate lyase activity [GO:0008813] (molecular_function)' has 'has output' relationship to 'pyruvate [CHEBI:15361] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'NAD(1-) [CHEBI:57540] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: 4-coumarate-CoA ligase activity [GO:0016207] (molecular_function) —has input→ coenzyme A(4-) [CHEBI:57287] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ ubiquinone biosynthetic process [GO:0006744] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ trans-4-coumarate [CHEBI:12876] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'acetyl-CoA(4-) [CHEBI:57288] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject '4-coumarate-CoA ligase activity [GO:0016207] (molecular_function)' has 'has input' relationship to 'coenzyme A(4-) [CHEBI:57287] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: geranylfarnesyl diphosphate synthase activity [GO:0044687] (molecular_function) —part of→ ubiquinone biosynthetic process [GO:0006744] (biological_process) 
YeastPathways_PWY3O-69
 superpathway of heme and siroheme biosynthesis - imported from: Saccharomyces Genome Database 2024-07-17 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-261
 superpathway of serine and glycine biosynthesis - imported from: Saccharomyces Genome Database 2024-07-17 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations 
YeastPathways_PWY3O-45
 folate biosynthesis II - imported from: Saccharomyces Genome Database 2024-07-16 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations
22 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —part of→ folic acid biosynthetic process [GO:0046656] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '7,8-dihydroneopterin [CHEBI:17001] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has output→ 7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'water [CHEBI:15377] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has input' relationship to '7,8-dihydroneopterin 3'-triphosphate(4-) [CHEBI:58462] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has input→ 7,8-dihydroneopterin 3'-triphosphate(4-) [CHEBI:58462] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has output→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ water [CHEBI:15377] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'hydrogenphosphate [CHEBI:43474] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has output' relationship to '7,8-dihydroneopterin 3'-phosphate(2-) [CHEBI:58762] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ 7,8-dihydroneopterin [CHEBI:17001] (chemical entity)
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has output' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function)' has 'has output' relationship to 'diphosphoric acid [CHEBI:29888] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ hydrogenphosphate [CHEBI:43474] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ folic acid biosynthetic process [GO:0046656] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: dihydroneopterin triphosphate pyrophosphohydrolase activity [GO:0019177] (molecular_function) —has output→ diphosphoric acid [CHEBI:29888] (chemical entity) 
YeastPathways_PWY3O-4115
 phenylalanine degradation - imported from: Saccharomyces Genome Database 2024-07-16 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations 
YeastPathways_PWY3O-2220
 salvage pathways of adenine, hypoxanthine and their nucleosides - imported from: Saccharomyces Genome Database 2024-07-16 Curators at SGD, Stacia Engel filtered Model has at least one activity with no causal relations 
YeastPathways_PWY3O-114
 superpathway of glutathione metabolism (truncated &gamma;-glutamyl cycle) - imported from: Saccharomyces Genome Database 2024-07-16 Curators at SGD, Stacia Engel success 
YeastPathways_PWY3O-19
 ubiquinol-6 biosynthesis from 4-hydroxybenzoate (eukaryotic) - imported from: Saccharomyces Genome Database 2024-07-16 Curators at SGD, Stacia Engel success
10 warnings
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ hydron [CHEBI:15378] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —part of→ biosynthetic process [GO:0009058] (biological_process)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to '2-hexaprenyl-6-methoxyphenol [CHEBI:1109] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —occurs in→ cytosol [GO:0005829] (anatomical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ 2-hexaprenyl-6-methoxyphenol [CHEBI:1109] (chemical entity)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has input→ 3-hexaprenyl-4-hydroxy-5-methoxybenzoate [CHEBI:57916] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to 'hydron [CHEBI:15378] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event) —has output→ carbon dioxide [CHEBI:16526] (chemical entity)
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has input' relationship to '3-hexaprenyl-4-hydroxy-5-methoxybenzoate [CHEBI:57916] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • SKIPPED_FACT: Subject 'Molecular Event [obo:go/extensions/reacto.owl#molecular_event] (Molecular Event)' has 'has output' relationship to 'carbon dioxide [CHEBI:16526] (chemical entity)', but that subject is not the molecular function of an activity unit; skipping molecular association 
66187e4700000078
 TREM2 activated by SEMA6D:PLXN1A in dendritic cell. (Human) 2024-04-25 Cristina Casals, Suzi Aleksander success 
632cf60a00000028
 mRNA editing enabled by APOBEC1 (Human) 2023-07-20 Lionel Breuza, Suzi Aleksander success 
62d0afa500001077
 Insulin-like growth factor receptor signaling pathway 1 (Mouse) 2023-07-07 David Hill, Suzi Aleksander success 
648d0dc100001547
 Epstein-Barr BILF1 inhibition of NLRP3 inflammasome via MAVS UFMylation (Human-EBV) 2023-06-27 Patrick Masson, Suzi Aleksander success
1 warning
  • UNKNOWN_ENABLED_BY_TYPE: 'UniProtKB:P03208' is used in enabled by relationship, but it is not of type protein-containing complex [GO:0032991] or information biomacromolecule [CHEBI:33695]; assuming information biomacromolecule / gene product. 
617b481400002798
 enabled by NSE5 Scer 2023-03-16 Marek Skrzypek success 
600ced8500002202
 TAG1 (YLR173W) regulates autophagy termination 2023-03-16 Suzi Aleksander success
5 warnings
  • SKIPPED_FACT: Subject 'protein localization to phagophore assembly site [GO:0034497] (biological_process)' has 'has input' relationship to 'ATG13 Scer [SGD:S000006389] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: protein serine/threonine kinase activity [GO:0004674] (molecular_function) —causally upstream of negative effect→ protein localization to phagophore assembly site [GO:0034497] (biological_process)
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: protein localization to phagophore assembly site [GO:0034497] (biological_process) —has input→ ATG13 Scer [SGD:S000006389] (information biomacromolecule)
  • SKIPPED_FACT: Subject 'protein localization to phagophore assembly site [GO:0034497] (biological_process)' has 'has input' relationship to 'ATG2 Scer [SGD:S000005186] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
  • UNHANDLED_FACT: Fact not representable in GO-CAM model: protein localization to phagophore assembly site [GO:0034497] (biological_process) —has input→ ATG2 Scer [SGD:S000005186] (information biomacromolecule)
Release date
2026-08-28
Pipeline name
pipeline-from-goa
Pipeline branch
main
Generated on
2026-08-29T14:10:14+00:00
gocam-py version
0.12.0.post65.dev0+8382d25a