583f430000000041
|
ZDB-PUB-160610-16 myb, cebp1 and neutrophil maturation |
2026-07-14 |
David Hill, Doug Howe, Sabrina Toro |
success |
|
1 warning
-
UNHANDLED_FACT: Fact not representable in GO-CAM model: cell maturation [GO:0048469] (biological_process) —results in maturation of→ neutrophil [CL:0000775] (anatomical entity)
|
5e72450500002719
|
SIN3A corepression of STAT3-dependent SOCS3 expression |
2026-07-03 |
Colin Logie, Pascale Gaudet |
success |
|
|
646ff70100004144
|
Major histocompatibility complex class I (MHC I) peptide loading (Human) |
2026-06-18 |
Lionel Breuza, Pascale Gaudet |
success |
|
|
67e5e74400002932
|
DNA-dependent histone reading by MSL3 |
2026-06-11 |
Colin Logie, Pascale Gaudet |
success |
|
|
67e5e74400000208
|
Sgf29 H3K4me3 reading recruits SAGA H3 HAT writer |
2026-06-11 |
Colin Logie, Pascale Gaudet |
success |
|
|
6205c24300000050
|
SIRT6 inactivation by lncPRESS1 RNA (Human) |
2026-05-05 |
Pascale Gaudet, Sylvain Poux |
success |
|
|
5f46c3b700001031
|
MYD88-dependent TLR4 signaling pathway leading to NF-kappa-B activation (Human) |
2026-04-27 |
Cristina Casals, Kimberly Van Auken, Pascale Gaudet, Patrick Masson |
success |
|
|
617b481400000460
|
KAT5 involvement in DNA repair via homologous recombination (Human) |
2026-04-19 |
Pascale Gaudet, Sylvain Poux |
success |
|
|
62900b6400001385
|
Lysosome biogenesis by TFEB and regulation of cytoplasmic retention via phosphorylation by MTOR or alkylation (Human) |
2026-04-16 |
Pascale Gaudet, Sylvain Poux |
success |
|
4 warnings
-
UNHANDLED_FACT: Fact not representable in GO-CAM model: negative regulation of protein localization to nucleus [GO:1900181] (biological_process) —has input→ TFEB Hsap [UniProtKB:P19484] (information biomacromolecule)
-
SKIPPED_FACT: Subject 'negative regulation of protein localization to nucleus [GO:1900181] (biological_process)' has 'has input' relationship to 'TFEB Hsap [UniProtKB:P19484] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
-
SKIPPED_FACT: Subject 'negative regulation of protein localization to nucleus [GO:1900181] (biological_process)' has 'has input' relationship to 'TFEB Hsap [UniProtKB:P19484] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
-
SKIPPED_FACT: Subject 'negative regulation of protein localization to nucleus [GO:1900181] (biological_process)' has 'has input' relationship to 'TFEB Hsap [UniProtKB:P19484] (information biomacromolecule)', but that subject is not the molecular function of an activity unit; skipping molecular association
|
5323da1800000002
|
NEDD4-model1 |
2026-03-24 |
Kimberly Van Auken, Pascale Gaudet, Paul Thomas, Rama Balakrishnan, Seth Carbon |
success |
|
|
60ad85f700001873
|
epidermal growth factor receptor signaling pathway via spi-Egfr (D.mel) |
2026-03-12 |
Helen Attrill, Pascale Gaudet |
success |
|
4 warnings
-
SKIPPED_FACT: 'DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'epidermal growth factor receptor signaling pathway [GO:0007173] (biological_process)'
-
SKIPPED_FACT: 'DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'negative regulation of transcription by RNA polymerase II [GO:0000122] (biological_process)'
-
SKIPPED_FACT: 'transcription corepressor activity [GO:0003714] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'negative regulation of transcription by RNA polymerase II [GO:0000122] (biological_process)'
-
SKIPPED_FACT: 'DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'positive regulation of transcription by RNA polymerase II [GO:0045944] (biological_process)'
|
6205c24300001663
|
IL2 signaling pathway (Human) |
2026-03-12 |
Pascale Gaudet, Patrick Masson |
success |
|
|
5ee8120100002841
|
Inflammatory signaling involved in regulation of hematopoietic stem cell differentiation via notch1a, tnfa, tnfrsf1b, jag1a (D.rerio) |
2026-03-12 |
Sabrina Toro, Sridhar Ramachandran |
success |
|
4 warnings
-
UNHANDLED_FACT: Fact not representable in GO-CAM model: Notch signaling pathway [GO:0007219] (biological_process) —occurs in→ hematopoietic stem cell [ZFA:0009014] (anatomical entity)
-
UNHANDLED_FACT: Fact not representable in GO-CAM model: signaling receptor activity [GO:0038023] (molecular_function) —causally upstream of or within positive effect→ regulation of non-canonical NF-kappaB signal transduction [GO:1901222] (biological_process)
-
UNHANDLED_FACT: Fact not representable in GO-CAM model: regulation of non-canonical NF-kappaB signal transduction [GO:1901222] (biological_process) —occurs in→ hematopoietic stem cell [ZFA:0009014] (anatomical entity)
-
UNHANDLED_FACT: Fact not representable in GO-CAM model: regulation of non-canonical NF-kappaB signal transduction [GO:1901222] (biological_process) —part of→ hematopoietic stem cell differentiation [GO:0060218] (biological_process)
|
59dc728000000351
|
GPCR - AC activating |
2026-02-26 |
Kimberly Van Auken, Pascale Gaudet |
success |
|
1 warning
-
SKIPPED_FACT: 'adenylate cyclase activity [GO:0004016] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189] (biological_process)'
|
60e7989d00000165
|
dTMP biosynthetic process1A (Mouse) |
2026-01-08 |
David Hill |
success |
|
2 warnings
-
UNHANDLED_FACT: Fact not representable in GO-CAM model: Rrm2 Mmus [MGI:MGI:98181] (information biomacromolecule) —part of→ ribonucleoside-diphosphate reductase complex [GO:0005971] (cellular_component)
-
UNHANDLED_FACT: Fact not representable in GO-CAM model: Rrm1 Mmus [MGI:MGI:98180] (information biomacromolecule) —part of→ ribonucleoside-diphosphate reductase complex [GO:0005971] (cellular_component)
|
6606056e00000903
|
Activation of the integrated stress response via activation of EIF2AK1/HRI by DELE1 in response to mitochondrial stress (Human) |
2025-10-03 |
Kimberly Van Auken, Pascale Gaudet, Sylvain Poux |
success |
|
|
67f85f2b00000093
|
H3K4me3 regulation by H3R2 methylation (yeast) |
2025-04-15 |
Pascale Gaudet |
success |
|
|
6494e2e900000134
|
Regulation of IRF7 activation by enterovirus D68 protein VP3 (Human-enterovirus) |
2025-04-01 |
Pascale Gaudet, Patrick Masson |
filtered |
Model has at least one activity with no causal relations |
|
67e5e74400000148
|
Arabidopsis MRG domain proteins bridge two histone modifications |
2025-03-28 |
Pascale Gaudet |
success |
|
|
5b528b1100001803
|
ZDB-PUB-170910-4 |
2023-07-20 |
Leyla Ruzicka, Sabrina Toro |
success |
|
5 warnings
-
UNHANDLED_FACT: Fact not representable in GO-CAM model: transforming growth factor beta receptor signaling pathway [GO:0007179] (biological_process) —part of→ mesodermal cell fate specification [GO:0007501] (biological_process)
-
UNHANDLED_FACT: Fact not representable in GO-CAM model: DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981] (molecular_function) —causally upstream of or within positive effect→ transforming growth factor beta receptor signaling pathway [GO:0007179] (biological_process)
-
SKIPPED_FACT: 'DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'transforming growth factor beta receptor signaling pathway [GO:0007179] (biological_process)'
-
SKIPPED_FACT: 'DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981] (molecular_function)' already has 'part of' relationship; ignoring 'part of' relationship to 'transforming growth factor beta receptor signaling pathway [GO:0007179] (biological_process)'
-
UNHANDLED_FACT: Fact not representable in GO-CAM model: transforming growth factor beta receptor signaling pathway [GO:0007179] (biological_process) —part of→ endodermal cell fate specification [GO:0001714] (biological_process)
|
6482692800001927
|
FOXP3 prevents HDAC2 from deacetylating a regulatory region in the p21 intron |
2023-06-14 |
Pascale Gaudet |
success |
|
|
63f809ec00001779
|
SLC17A9 regulates P2RX4 (Mouse) |
2023-06-13 |
Lionel Breuza, Pascale Gaudet |
success |
|
|
62183af000000874
|
miRNA maturation by TRUB1 (Human) |
2023-03-16 |
Paul Thomas, Sylvain Poux |
success |
|
|
62b4ffe300002340
|
Penicillin G from Penicillium chrysogenum |
2022-07-07 |
Marc Feuermann, Pascale Gaudet |
success |
|
|