| gomodel:5323da1800000002 |
NEDD4-model1 |
production |
gomodel:5323da1800000002/5323da180000008 |
GO:0005665 |
RNA polymerase II, core complex |
GO:0003899 |
DNA-directed RNA polymerase activity |
Kimberly Van Auken |
WB |
| gomodel:5b528b1100001803 |
ZDB-PUB-170910-4 |
production |
gomodel:5b528b1100001803/5fce9b7300001103 |
GO:0005667 |
transcription regulator complex |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
Sabrina Toro |
ZFIN |
| gomodel:5b528b1100001803 |
ZDB-PUB-170910-4 |
production |
gomodel:5b528b1100001803/5fce9b7300001109 |
GO:0005667 |
transcription regulator complex |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
Sabrina Toro |
ZFIN |
| gomodel:5b528b1100002293 |
ZDB-PUB-171204-53 |
production |
gomodel:5b528b1100002293/5b528b1100002301 |
GO:0032991 |
protein-containing complex |
GO:0036002 |
pre-mRNA binding |
Sabrina Toro |
ZFIN |
| gomodel:5ed1aab700000290 |
Sodium transport in kidney |
production |
gomodel:5ed1aab700000290/5ed1aab700000324 |
GO:0034706 |
sodium channel complex |
GO:0015081 |
sodium ion transmembrane transporter activity |
David Hill |
MGI |
| gomodel:5fadbcf000000632 |
p38MAPK cascade (GO:0038066) |
production |
gomodel:5fadbcf000000632/69729a3800002171 |
GO:0000308 |
cytoplasmic cyclin-dependent protein kinase holoenzyme complex |
GO:0004693 |
cyclin-dependent protein serine/threonine kinase activity |
Val Wood |
PomBase |
| gomodel:5fb9cc0600000156 |
circadian rhythm and hematopoiesis via ezh2, per1b, cry1a etc. (D. rerio) |
production |
gomodel:5fb9cc0600000156/5fb9cc0600000202 |
GO:1990513 |
CLOCK-BMAL transcription complex |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
Sabrina Toro |
ZFIN |
| gomodel:5fb9cc0600000156 |
circadian rhythm and hematopoiesis via ezh2, per1b, cry1a etc. (D. rerio) |
production |
gomodel:5fb9cc0600000156/5fb9cc0600000160 |
GO:1990513 |
CLOCK-BMAL transcription complex |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
Sabrina Toro |
ZFIN |
| gomodel:5fb9cc0600000156 |
circadian rhythm and hematopoiesis via ezh2, per1b, cry1a etc. (D. rerio) |
production |
gomodel:5fb9cc0600000156/60747c4200000589 |
GO:1990513 |
CLOCK-BMAL transcription complex |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
Sabrina Toro |
ZFIN |
| gomodel:5fb9cc0600000156 |
circadian rhythm and hematopoiesis via ezh2, per1b, cry1a etc. (D. rerio) |
production |
gomodel:5fb9cc0600000156/60747c4200000588 |
GO:1990513 |
CLOCK-BMAL transcription complex |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
Sabrina Toro |
ZFIN |
| gomodel:5fb9cc0600000156 |
circadian rhythm and hematopoiesis via ezh2, per1b, cry1a etc. (D. rerio) |
production |
gomodel:5fb9cc0600000156/60747c4200000587 |
GO:1990513 |
CLOCK-BMAL transcription complex |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
Sabrina Toro |
ZFIN |
| gomodel:5fb9cc0600000727 |
Triacyl lipopetide activation of TLR1-TLR2 complex (Human) |
production |
gomodel:5fb9cc0600000727/663d668500002682 |
GO:0035354 |
Toll-like receptor 1-Toll-like receptor 2 protein complex |
GO:0001875 |
lipopolysaccharide immune receptor activity |
Patrick Masson |
UniProt |
| gomodel:5fce9b7300000030 |
Diacyl lipopeptide and bacteriocin activation of TLR6_TLR2 receptor (Human)
|
production |
gomodel:5fce9b7300000030/663d668500002718 |
GO:0035355 |
Toll-like receptor 2-Toll-like receptor 6 protein complex |
GO:0001875 |
lipopolysaccharide immune receptor activity |
Patrick Masson |
UniProt |
| gomodel:60e7989d00000165 |
dTMP biosynthetic process1A (Mouse) |
production |
gomodel:60e7989d00000165/60e7989d00000176 |
GO:0005971 |
ribonucleoside-diphosphate reductase complex |
GO:0036175 |
ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor |
David Hill |
MGI |
| gomodel:617b481400002798 |
enabled by NSE5 Scer |
production |
gomodel:617b481400002798/617b481400002813 |
SGD:S000217717 |
|
GO:0003677 |
DNA binding |
Marek Skrzypek |
SGD |
| gomodel:61b2b68300000156 |
signaling receptor ligand precursor processing 1 (Mouse) |
production |
gomodel:61b2b68300000156/61b2b68300000169 |
GO:0070765 |
gamma-secretase complex |
GO:0008233 |
peptidase activity |
David Hill |
MGI |
| gomodel:61e0e55600000900 |
TK1 in mitotic cell cycle phase transition (Human) |
production |
gomodel:61e0e55600000900/61e0e55600001064 |
GO:0016602 |
CCAAT-binding factor complex |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
Cristina Casals |
UniProt |
| gomodel:61f34dd300000000 |
Nuclear import of the proteasome by AKIRIN2 (Human) |
production |
gomodel:61f34dd300000000/61f34dd300000026 |
GO:0005839 |
proteasome core complex |
GO:0004175 |
endopeptidase activity |
Sylvain Poux |
UniProt |
| gomodel:61f34dd300000787 |
IL23 signaling pathway (Human) |
production |
gomodel:61f34dd300000787/665912ed00000000 |
ComplexPortal:CPX-3290 |
|
GO:0005125 |
cytokine activity |
Patrick Masson |
UniProt |
| gomodel:623d156d00000817 |
Role of TONSL and MMS22L (TONSL-MMS22L complex) in promoting homologous recombination-mediated repair of DSBs (Human) |
production |
gomodel:623d156d00000817/623d156d00000886 |
GO:0005662 |
DNA replication factor A complex |
GO:0003682 |
chromatin binding |
Sylvain Poux |
UniProt |
| gomodel:62900b6400001630 |
PTEN in excitatory hippocampal synapse long-term depression (Human) |
production |
gomodel:62900b6400001630/62900b6400001636 |
GO:0017146 |
NMDA selective glutamate receptor complex |
GO:0004972 |
NMDA glutamate receptor activity |
Cristina Casals |
UniProt |
| gomodel:62900b6400001631 |
Mycophenolic acid - Penicillium brevicompactum |
production |
gomodel:62900b6400001631/62b4ffe300002439 |
GO:0036125 |
fatty acid beta-oxidation multienzyme complex |
GO:0003857 |
(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity |
Marc Feuermann |
UniProt |
| gomodel:62900b6400001631 |
Mycophenolic acid - Penicillium brevicompactum |
production |
gomodel:62900b6400001631/62b4ffe300002432 |
GO:0036125 |
fatty acid beta-oxidation multienzyme complex |
GO:0004300 |
enoyl-CoA hydratase activity |
Marc Feuermann |
UniProt |
| gomodel:62900b6400001631 |
Mycophenolic acid - Penicillium brevicompactum |
production |
gomodel:62900b6400001631/62b4ffe300002446 |
GO:0036125 |
fatty acid beta-oxidation multienzyme complex |
GO:0003988 |
acetyl-CoA C-acyltransferase activity |
Marc Feuermann |
UniProt |
| gomodel:62b4ffe300002959 |
Aflaroxin (Aspergillus parasiticus) |
production |
gomodel:62b4ffe300002959/62b4ffe300004811 |
GO:0005835 |
fatty acid synthase complex |
GO:0004312 |
fatty acid synthase activity |
Marc Feuermann |
UniProt |
| gomodel:62f58d8800001119 |
Insulin receptor recycling (Mouse) |
production |
gomodel:62f58d8800001119/62f58d8800001131 |
GO:0033176 |
proton-transporting V-type ATPase complex |
GO:0015078 |
proton transmembrane transporter activity |
David Hill |
MGI |
| gomodel:62f58d8800001119 |
Insulin receptor recycling (Mouse) |
production |
gomodel:62f58d8800001119/62f58d8800001181 |
GO:0033180 |
proton-transporting V-type ATPase, V1 domain |
GO:0016887 |
ATP hydrolysis activity |
David Hill |
MGI |
| gomodel:62f58d8800001738 |
Gut Microbiota tryptophan metabolism: Regulation of intestinal transit by 5-hydroxy-L-tryptophan(Human-E.coli) |
production |
gomodel:62f58d8800001738/62f58d8800001778 |
GO:1990454 |
L-type voltage-gated calcium channel complex |
GO:0005262 |
calcium channel activity |
Cristina Casals |
UniProt |
| gomodel:62f58d8800002184 |
positive regulation of insulin secretion involved in cellular response to glucose stimulus (Mouse) |
production |
gomodel:62f58d8800002184/62f58d8800002323 |
GO:0005891 |
voltage-gated calcium channel complex |
GO:0005245 |
voltage-gated calcium channel activity |
David Hill |
MGI |
| gomodel:62f58d8800002184 |
positive regulation of insulin secretion involved in cellular response to glucose stimulus (Mouse) |
production |
gomodel:62f58d8800002184/62f58d8800002191 |
GO:0005891 |
voltage-gated calcium channel complex |
GO:0005245 |
voltage-gated calcium channel activity |
David Hill |
MGI |
| gomodel:62f58d8800002367 |
Protein import into peroxisomes of PTS1-containing proteins by the PEX5 receptor, and recycling of the PEX5 receptor (S.cerevisiae) |
production |
gomodel:62f58d8800002367/62f58d8800002455 |
GO:1990429 |
peroxisomal importomer complex |
GO:0008320 |
transmembrane protein transporter activity |
Sylvain Poux |
UniProt |
| gomodel:62f58d8800002367 |
Protein import into peroxisomes of PTS1-containing proteins by the PEX5 receptor, and recycling of the PEX5 receptor (S.cerevisiae) |
production |
gomodel:62f58d8800002367/62f58d8800002425 |
GO:1904949 |
ATPase complex |
GO:0140567 |
membrane protein dislocase activity |
Sylvain Poux |
UniProt |
| gomodel:62f58d8800002367 |
Protein import into peroxisomes of PTS1-containing proteins by the PEX5 receptor, and recycling of the PEX5 receptor (S.cerevisiae) |
production |
gomodel:62f58d8800002367/62f58d8800002379 |
GO:1990429 |
peroxisomal importomer complex |
GO:0008320 |
transmembrane protein transporter activity |
Sylvain Poux |
UniProt |
| gomodel:62f58d8800006739 |
Negative regulation of insulin secretion 2 (Mouse) |
production |
gomodel:62f58d8800006739/62f58d8800006749 |
GO:0031680 |
G-protein beta/gamma-subunit complex |
GO:0140678 |
molecular function inhibitor activity |
David Hill |
MGI |
| gomodel:633b013300000306 |
Tricarboxylic acid cycle 1 (Mouse) |
production |
gomodel:633b013300000306/633b013300000456 |
GO:0045273 |
respiratory chain complex II (succinate dehydrogenase) |
GO:0008177 |
succinate dehydrogenase (quinone) activity |
David Hill |
MGI |
| gomodel:633b013300000306 |
Tricarboxylic acid cycle 1 (Mouse) |
production |
gomodel:633b013300000306/633b013300000457 |
GO:0009361 |
succinate-CoA ligase complex (ADP-forming) |
GO:0004775 |
succinate-CoA ligase (ADP-forming) activity |
David Hill |
MGI |
| gomodel:633b013300000306 |
Tricarboxylic acid cycle 1 (Mouse) |
production |
gomodel:633b013300000306/633b013300000461 |
GO:0045244 |
succinate-CoA ligase complex (GDP-forming) |
GO:0004776 |
succinate-CoA ligase (GDP-forming) activity |
David Hill |
MGI |
| gomodel:63e5937500001279 |
Extraction of mRNA from stalled ribosomes by the SKI complex, leading to recruitment of the PELO-HBS1L complex that binds to stalled ribosomes, followed by ribosome dissociation by ABCE1 (Human) |
production |
gomodel:63e5937500001279/63e5937500001307 |
GO:0055087 |
Ski complex |
GO:0034458 |
3'-5' RNA helicase activity |
Sylvain Poux |
UniProt |
| gomodel:646ff70100000049 |
Antibacterial innate immune response to muramyl dipeptide. (Human) |
production |
gomodel:646ff70100000049/646ff70100000050 |
ComplexPortal:CPX-892 |
|
GO:0004888 |
transmembrane signaling receptor activity |
Cristina Casals |
UniProt |
| gomodel:646ff70100000391 |
Canonical mTORC1 signaling (Human) |
production |
gomodel:646ff70100000391/646ff70100000392 |
GO:0071986 |
Ragulator complex |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
Sylvain Poux |
UniProt |
| gomodel:646ff70100000611 |
Ubiquitination of RagA/RRAGA by RNF152 inhibits the mTORC1 signaling (Human) |
production |
gomodel:646ff70100000611/646ff70100000825 |
GO:1990130 |
GATOR1 complex |
GO:0005096 |
GTPase activator activity |
Sylvain Poux |
UniProt |
| gomodel:646ff70100001312 |
Inhibition of the canonical mTORC1 signaling by the GATOR1 complex (Human) |
production |
gomodel:646ff70100001312/646ff70100001512 |
GO:0140007 |
KICSTOR complex |
GO:0043495 |
protein-membrane adaptor activity |
Sylvain Poux |
UniProt |
| gomodel:646ff70100001877 |
Inhibition of the canonical mTORC1 signaling via ubiquitination and degradation of LAMTOR1 by UBE3A (Human) |
production |
gomodel:646ff70100001877/646ff70100001878 |
GO:0071986 |
Ragulator complex |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
Sylvain Poux |
UniProt |
| gomodel:646ff70100002094 |
Negative regulation of the canonical mTORC1 signaling via phosphorylation of LAMTOR4 by PKA (Human) |
production |
gomodel:646ff70100002094/646ff70100002298 |
GO:0005952 |
cAMP-dependent protein kinase complex |
GO:0106310 |
protein serine kinase activity |
Sylvain Poux |
UniProt |
| gomodel:646ff70100002094 |
Negative regulation of the canonical mTORC1 signaling via phosphorylation of LAMTOR4 by PKA (Human) |
production |
gomodel:646ff70100002094/646ff70100002095 |
GO:0071986 |
Ragulator complex |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
Sylvain Poux |
UniProt |
| gomodel:646ff70100002557 |
Negative regulation of autophagy via phosphorylation of ULK1 by canonical mTORC1 signaling (Human) |
production |
gomodel:646ff70100002557/646ff70100002558 |
GO:0071986 |
Ragulator complex |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
Sylvain Poux |
UniProt |
| gomodel:6482692800000498 |
Activation of the canonical mTORC1 signaling by GPR155/LYCHOS in response to cholesterol influx (Human) |
production |
gomodel:6482692800000498/6482692800000642 |
GO:0140007 |
KICSTOR complex |
GO:0043495 |
protein-membrane adaptor activity |
Sylvain Poux |
UniProt |
| gomodel:6482692800000701 |
Activation of the canonical mTORC1 signaling by BMT2/SAMTOR in response to S-adenosyl-L-methionine influx (Human) |
production |
gomodel:6482692800000701/6482692800000845 |
GO:0140007 |
KICSTOR complex |
GO:0043495 |
protein-membrane adaptor activity |
Sylvain Poux |
UniProt |
| gomodel:64c3044100000910 |
cGAS-STING signaling in the nucleus (Human) |
production |
gomodel:64c3044100000910/6918f23700000949 |
GO:0000786 |
nucleosome |
GO:0140678 |
molecular function inhibitor activity |
Sylvain Poux |
UniProt |
| gomodel:64e7eefa00000854 |
Tumor necrosis factor-mediated signaling pathway 1 (Mouse) |
production |
gomodel:64e7eefa00000854/64e7eefa00000908 |
GO:0035525 |
NF-kappaB p50/p65 complex |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
David Hill |
MGI |
| gomodel:65039e8700000196 |
HTATSF1 and TOPBP1 promote RPA-RAD51 exchange in double-strand break repair via homologous recombination (Human). |
production |
gomodel:65039e8700000196/65039e8700000242 |
GO:0005662 |
DNA replication factor A complex |
GO:0003684 |
damaged DNA binding |
Sylvain Poux |
UniProt |
| gomodel:654d809000000112 |
SQSTM1 is involved in aggrephagy by mediating recruitment of ubiquitinated proteins to autophagosomes (Human). |
production |
gomodel:654d809000000112/654d809000000145 |
GO:0000151 |
ubiquitin ligase complex |
GO:0061630 |
ubiquitin protein ligase activity |
Sylvain Poux |
UniProt |
| gomodel:65692e7e00000243 |
Activation of the canonical mTORC1 signaling by PRMT1 in response to S-adenosyl-L-methionine influx (Human) |
production |
gomodel:65692e7e00000243/65692e7e00000387 |
GO:0140007 |
KICSTOR complex |
GO:0043495 |
protein-membrane adaptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:65a1f4f800000855 |
Initiation of double-strand break repair via homologous recombination by the MRN complex (MRE11-RAD50-NBN) (Human). |
production |
gomodel:65a1f4f800000855/65a1f4f800000890 |
GO:0030870 |
Mre11 complex |
GO:0043539 |
protein serine/threonine kinase activator activity |
Sylvain Poux |
UniProt |
| gomodel:65a1f4f800001029 |
SKP2 mediates 'Lys-63'-linked ubiquitination of NBN, promoting double-strand break repair via homologous recombination (Human). |
production |
gomodel:65a1f4f800001029/65a1f4f800001042 |
GO:0030870 |
Mre11 complex |
GO:0043539 |
protein serine/threonine kinase activator activity |
Sylvain Poux |
UniProt |
| gomodel:65a1f4f800001246 |
Lactylation of MRE11 by CREBBP and NBN by KAT5 in response to DNA damage promotes double-strand break repair via homologous recombination (Human). |
production |
gomodel:65a1f4f800001246/65a1f4f800001256 |
GO:0030870 |
Mre11 complex |
GO:0043539 |
protein serine/threonine kinase activator activity |
Sylvain Poux |
UniProt |
| gomodel:65a1f4f800002560 |
Ufmylation of MRE11 promotes ATM activation by the MRN complex (MRE11-RAD50-NBN) (Human). |
production |
gomodel:65a1f4f800002560/65a1f4f800002570 |
GO:0030870 |
Mre11 complex |
GO:0043539 |
protein serine/threonine kinase activator activity |
Sylvain Poux |
UniProt |
| gomodel:65a1f4f800002665 |
Sumoylation of MRE11 by PIAS1 promotes retention of the MRN complex (MRE11-RAD50-NBN) to DNA damage sites (Human). |
production |
gomodel:65a1f4f800002665/65a1f4f800002675 |
GO:0030870 |
Mre11 complex |
GO:0043539 |
protein serine/threonine kinase activator activity |
Sylvain Poux |
UniProt |
| gomodel:65bc474400000955 |
Negative regulation of Hippo signaling by STRIPAK complex via STRN4:MAP4K4(Human). |
production |
gomodel:65bc474400000955/65bc474400001102 |
GO:0090443 |
FAR/SIP/STRIPAK complex |
GO:0030674 |
protein-macromolecule adaptor activity |
Cristina Casals |
UniProt |
| gomodel:65c57c3400000270 |
Sxl and Unr inhibit translation of msl-2 transcripts in females (D.melanogaster). |
production |
gomodel:65c57c3400000270/65c57c3400000306 |
GO:0016281 |
eukaryotic translation initiation factor 4F complex |
GO:0003743 |
translation initiation factor activity |
Sylvain Poux |
UniProt |
| gomodel:65c57c3400001478 |
Negative regulation of Hippo signaling by SLMAP-STRIPAK complex (Human). |
production |
gomodel:65c57c3400001478/65c57c3400001633 |
GO:0090443 |
FAR/SIP/STRIPAK complex |
GO:0004722 |
protein serine/threonine phosphatase activity |
Cristina Casals |
UniProt |
| gomodel:65f3ae5c00000170 |
Ufmylation of RPL26 following translation termination promotes 60S ribosomal subunit recycling (Human). |
production |
gomodel:65f3ae5c00000170/65f3ae5c00000223 |
GO:0022625 |
cytosolic large ribosomal subunit |
GO:0003735 |
structural constituent of ribosome |
Sylvain Poux |
UniProt |
| gomodel:65f3ae5c00000170 |
Ufmylation of RPL26 following translation termination promotes 60S ribosomal subunit recycling (Human). |
production |
gomodel:65f3ae5c00000170/65f3ae5c00000215 |
GO:0022625 |
cytosolic large ribosomal subunit |
GO:0003735 |
structural constituent of ribosome |
Sylvain Poux |
UniProt |
| gomodel:65f3ae5c00000257 |
Ufmylation of RPL26 following ribosome stalling promotes 60S ribosomal subunit recycling (Human). |
production |
gomodel:65f3ae5c00000257/65f3ae5c00000308 |
GO:0022625 |
cytosolic large ribosomal subunit |
GO:0003735 |
structural constituent of ribosome |
Sylvain Poux |
UniProt |
| gomodel:65f3ae5c00000257 |
Ufmylation of RPL26 following ribosome stalling promotes 60S ribosomal subunit recycling (Human). |
production |
gomodel:65f3ae5c00000257/65f3ae5c00000300 |
GO:0022625 |
cytosolic large ribosomal subunit |
GO:0003735 |
structural constituent of ribosome |
Sylvain Poux |
UniProt |
| gomodel:6606056e00000317 |
UBR4 and UBR5 catalyze branched-linked polyubiquitination of substrates, leading to proteasome-mediated degradation of substrates (Human). |
production |
gomodel:6606056e00000317/6606056e00000347 |
GO:0005839 |
proteasome core complex |
GO:0004175 |
endopeptidase activity |
Sylvain Poux |
UniProt |
| gomodel:6606056e00002011 |
CD72 and BCR co-stimulation by sn/RNP self antigen (Human) |
production |
gomodel:6606056e00002011/662af8fa00002857 |
GO:0019815 |
B cell receptor complex |
GO:0004888 |
transmembrane signaling receptor activity |
Patrick Masson |
UniProt |
| gomodel:66187e4700000078 |
TREM2 activated by SEMA6D:PLXN1A in dendritic cell. (Human) |
production |
gomodel:66187e4700000078/66187e4700000131 |
GO:0002116 |
semaphorin receptor complex |
GO:0017154 |
semaphorin receptor activity |
Cristina Casals |
UniProt |
| gomodel:66187e4700000318 |
The CRL5(ASB11) complex mediates ubiquitination and degradation of BIK in response to endoplasmic reticulum stress (Human). |
production |
gomodel:66187e4700000318/66187e4700000376 |
GO:0005839 |
proteasome core complex |
GO:0004175 |
endopeptidase activity |
Sylvain Poux |
UniProt |
| gomodel:66187e4700001274 |
N6 -methyladenosine-modified lncRNA ARHGAP5-AS1 stabilises CSDE1 and coordinates oncogenic RNA regulons in hepatocellular carcinoma. PMID:36354136. (Human) |
production |
gomodel:66187e4700001274/66187e4700001321 |
GO:0036396 |
RNA N6-methyladenosine methyltransferase complex |
GO:1990931 |
mRNA N6-methyladenosine dioxygenase activity |
Helen Attrill |
FlyBase |
| gomodel:66187e4700002284 |
septation initiation signaling (GO:0031028) |
production |
gomodel:66187e4700002284/67c10cc400002363 |
GO:0090443 |
FAR/SIP/STRIPAK complex |
GO:0004721 |
phosphoprotein phosphatase activity |
Pascal Carme |
PomBase |
| gomodel:66187e4700002284 |
septation initiation signaling (GO:0031028) |
production |
gomodel:66187e4700002284/67c10cc400007695 |
GO:1990334 |
SIN/MEN two-component GAP complex |
GO:0005096 |
GTPase activator activity |
Pascal Carme |
PomBase |
| gomodel:663d668500000596 |
oxidative phosphorylation (GO:0006119) |
production |
gomodel:663d668500000596/67369e7600000439 |
GO:0045259 |
proton-transporting ATP synthase complex |
GO:0046933 |
proton-transporting ATP synthase activity, rotational mechanism |
Val Wood |
PomBase |
| gomodel:663d668500000596 |
oxidative phosphorylation (GO:0006119) |
production |
gomodel:663d668500000596/67086be200000144 |
GO:0045277 |
respiratory chain complex IV |
GO:0004129 |
cytochrome-c oxidase activity |
Val Wood |
PomBase |
| gomodel:663d668500000596 |
oxidative phosphorylation (GO:0006119) |
production |
gomodel:663d668500000596/67086be200000116 |
GO:0045275 |
respiratory chain complex III |
GO:0008121 |
quinol-cytochrome-c reductase activity |
Val Wood |
PomBase |
| gomodel:663d668500000596 |
oxidative phosphorylation (GO:0006119) |
production |
gomodel:663d668500000596/66a3e0bb00002447 |
GO:0045273 |
respiratory chain complex II (succinate dehydrogenase) |
GO:0008177 |
succinate dehydrogenase (quinone) activity |
Val Wood |
PomBase |
| gomodel:663d668500002302 |
canonical glycolysis (GO:0061621) |
production |
gomodel:663d668500002302/69d8496c00001939 |
GO:7770001 |
mitochondrial pyruvate carrier complex |
GO:0050833 |
pyruvate transmembrane transporter activity |
Val Wood |
PomBase |
| gomodel:665912ed00000192 |
GPI anchored protein biosynthetic process (GO:0180046) |
production |
gomodel:665912ed00000192/6882d2b800004603 |
GO:0000506 |
glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex |
GO:0017176 |
phosphatidylinositol N-acetylglucosaminyltransferase activity |
Val Wood |
PomBase |
| gomodel:665912ed00000459 |
dolichol-linked oligosaccharide biosynthetic process (GO:0006488) (plus transfer and processing) |
production |
gomodel:665912ed00000459/68b0f0d000003429 |
GO:0008250 |
oligosaccharyltransferase complex |
GO:0004579 |
dolichyl-diphosphooligosaccharide-protein glycotransferase activity |
Val Wood |
PomBase |
| gomodel:665912ed00000652 |
pericentric heterochromatin formation (GO:0031508) |
production |
gomodel:665912ed00000652/67f85f2b00004476 |
GO:0070824 |
SHREC complex |
GO:0031078 |
histone H3K14 deacetylase activity, hydrolytic mechanism |
Pascal Carme |
PomBase |
| gomodel:665912ed00000652 |
pericentric heterochromatin formation (GO:0031508) |
production |
gomodel:665912ed00000652/67f85f2b00004057 |
GO:0043494 |
CLRC complex |
GO:0046974 |
histone H3K9 methyltransferase activity |
Pascal Carme |
PomBase |
| gomodel:665912ed00000652 |
pericentric heterochromatin formation (GO:0031508) |
production |
gomodel:665912ed00000652/67f85f2b00004081 |
GO:0035101 |
FACT complex |
GO:0000511 |
H2A-H2B histone complex chaperone activity |
Pascal Carme |
PomBase |
| gomodel:665912ed00001983 |
subtelomeric heterochromatin formation (GO:0031509) |
production |
gomodel:665912ed00001983/67f85f2b00004722 |
GO:0043494 |
CLRC complex |
GO:0046974 |
histone H3K9 methyltransferase activity |
Pascal Carme |
PomBase |
| gomodel:665912ed00001983 |
subtelomeric heterochromatin formation (GO:0031509) |
production |
gomodel:665912ed00001983/67f85f2b00004769 |
GO:0070824 |
SHREC complex |
GO:0031078 |
histone H3K14 deacetylase activity, hydrolytic mechanism |
Pascal Carme |
PomBase |
| gomodel:665912ed00001983 |
subtelomeric heterochromatin formation (GO:0031509) |
production |
gomodel:665912ed00001983/67f85f2b00004743 |
GO:0035101 |
FACT complex |
GO:0000511 |
H2A-H2B histone complex chaperone activity |
Pascal Carme |
PomBase |
| gomodel:665912ed00002626 |
nitrogen cycle metabolic process (GO:0071941), urate catabolic process (GO:0019628) |
production |
gomodel:665912ed00002626/6796b94c00006646 |
GO:0150006 |
urease activator complex |
GO:0018237 |
urease activator activity |
Pascal Carme |
PomBase |
| gomodel:668d5f2700000201 |
CMP-N-acetylneuraminate biosynthetic process (Mouse) |
production |
gomodel:668d5f2700000201/668d5f2700000272 |
GO:0005643 |
nuclear pore |
GO:0005215 |
transporter activity |
David Hill |
MGI |
| gomodel:668d5f2700000201 |
CMP-N-acetylneuraminate biosynthetic process (Mouse) |
production |
gomodel:668d5f2700000201/668d5f2700000280 |
GO:0005643 |
nuclear pore |
GO:0005215 |
transporter activity |
David Hill |
MGI |
| gomodel:6690711d00000596 |
NMDA glutamate receptor activity co-activated by glycine and involving GRIN1 and GRIN2A (human) |
production |
gomodel:6690711d00000596/6690711d00001413 |
GO:0017146 |
NMDA selective glutamate receptor complex |
GO:0004972 |
NMDA glutamate receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:6690711d00001433 |
Protein O-linked glycosylation 1 (Mouse) |
production |
gomodel:6690711d00001433/6690711d00001461 |
GO:0031502 |
dolichyl-phosphate-mannose-protein mannosyltransferase complex |
GO:0004169 |
dolichyl-phosphate-mannose-protein mannosyltransferase activity |
David Hill |
MGI |
| gomodel:6690711d00002607 |
ANG tRNA ribonuclease activity inhibits translation in response to stress (Human). |
production |
gomodel:6690711d00002607/6690711d00002632 |
GO:0022625 |
cytosolic large ribosomal subunit |
GO:0003735 |
structural constituent of ribosome |
Sylvain Poux |
UniProt |
| gomodel:6690711d00002607 |
ANG tRNA ribonuclease activity inhibits translation in response to stress (Human). |
production |
gomodel:6690711d00002607/6690711d00002639 |
GO:0022625 |
cytosolic large ribosomal subunit |
GO:0008428 |
ribonuclease inhibitor activity |
Sylvain Poux |
UniProt |
| gomodel:6690711d00002652 |
RNH1 inhibits the tRNA ribonuclease activity of ANG in the cytoplasm in absence of stress (Human). |
production |
gomodel:6690711d00002652/6690711d00002677 |
GO:0022625 |
cytosolic large ribosomal subunit |
GO:0003735 |
structural constituent of ribosome |
Sylvain Poux |
UniProt |
| gomodel:66a3e0bb00001342 |
'de novo' L-methionine biosynthetic process (GO:0071266), sulfate assimilation (GO:0000103), sulfite transmembrane transport. (GO:0000316), sulfate import across plasma membrane (GO:1902434) |
production |
gomodel:66a3e0bb00001342/6a4c244800004683 |
GO:0097361 |
cytosolic [4Fe-4S] assembly targeting complex |
GO:0036455 |
iron-sulfur transferase activity |
Val Wood |
PomBase |
| gomodel:66a3e0bb00001342 |
'de novo' L-methionine biosynthetic process (GO:0071266), sulfate assimilation (GO:0000103), sulfite transmembrane transport. (GO:0000316), sulfate import across plasma membrane (GO:1902434) |
production |
gomodel:66a3e0bb00001342/6a4c244800004658 |
GO:0009337 |
sulfite reductase complex (NADPH) |
GO:0004783 |
sulfite reductase (NADPH) activity |
Val Wood |
PomBase |
| gomodel:66a3e0bb00002104 |
ITPRIPL1 is a ligand of CD3E that negatively regulates TCR signaling pathway. (Human) |
production |
gomodel:66a3e0bb00002104/66a3e0bb00002124 |
GO:0042101 |
T cell receptor complex |
GO:0004888 |
transmembrane signaling receptor activity |
Cristina Casals |
UniProt |
| gomodel:66b5638000002701 |
IL13RA2-mediated alternative IL13 pathway leading to TGFB1 production (Human) |
production |
gomodel:66b5638000002701/66b5638000002727 |
GO:0035976 |
transcription factor AP-1 complex |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
Patrick Masson |
UniProt |
| gomodel:66b5638000002719 |
trans-synaptic complex NRXN1B-CBLN2-GRID1 regulates NMDAR signaling. (Human) |
production |
gomodel:66b5638000002719/66b5638000002809 |
GO:0017146 |
NMDA selective glutamate receptor complex |
GO:0004972 |
NMDA glutamate receptor activity |
Cristina Casals |
UniProt |
| gomodel:66b5638000002719 |
trans-synaptic complex NRXN1B-CBLN2-GRID1 regulates NMDAR signaling. (Human) |
production |
gomodel:66b5638000002719/66b5638000002794 |
GO:0098820 |
trans-synaptic protein complex |
GO:0030545 |
signaling receptor regulator activity |
Cristina Casals |
UniProt |
| gomodel:66b5638000002817 |
Trans-synaptic comples NRXN3B-CBLN2-GRID1 regulates AMPAR signaling. (Mouse) |
production |
gomodel:66b5638000002817/66b5638000002818 |
GO:0098820 |
trans-synaptic protein complex |
GO:0030545 |
signaling receptor regulator activity |
Cristina Casals |
UniProt |
| gomodel:66b5638000002817 |
Trans-synaptic comples NRXN3B-CBLN2-GRID1 regulates AMPAR signaling. (Mouse) |
production |
gomodel:66b5638000002817/66b5638000002833 |
GO:0032281 |
AMPA glutamate receptor complex |
GO:0004971 |
AMPA glutamate receptor activity |
Cristina Casals |
UniProt |
| gomodel:66b5638000002847 |
Trans-synaptic complex NRXN3B-CBLN2-GRID1 regulates AMPAR signaling. (Human) |
production |
gomodel:66b5638000002847/66b5638000002848 |
GO:0098820 |
trans-synaptic protein complex |
GO:0030545 |
signaling receptor regulator activity |
Cristina Casals |
UniProt |
| gomodel:66b5638000002847 |
Trans-synaptic complex NRXN3B-CBLN2-GRID1 regulates AMPAR signaling. (Human) |
production |
gomodel:66b5638000002847/66b5638000002856 |
GO:0032281 |
AMPA glutamate receptor complex |
GO:0004971 |
AMPA glutamate receptor activity |
Cristina Casals |
UniProt |
| gomodel:66b5638000002885 |
Trans-synaptic complex NRXN1B-CBLN2-GRID1 regulates NMDAR signaling. (Mouse) |
production |
gomodel:66b5638000002885/66b5638000002901 |
GO:0017146 |
NMDA selective glutamate receptor complex |
GO:0004972 |
NMDA glutamate receptor activity |
Cristina Casals |
UniProt |
| gomodel:66b5638000002885 |
Trans-synaptic complex NRXN1B-CBLN2-GRID1 regulates NMDAR signaling. (Mouse) |
production |
gomodel:66b5638000002885/66b5638000002886 |
GO:0098820 |
trans-synaptic protein complex |
GO:0030545 |
signaling receptor regulator activity |
Cristina Casals |
UniProt |
| gomodel:66c7d41500000016 |
Trans-synaptic complex NRXN1B-CBLN1-GRID2 regulates synaptogenesis. (Human) |
production |
gomodel:66c7d41500000016/66c7d41500000025 |
GO:0032281 |
AMPA glutamate receptor complex |
GO:0004971 |
AMPA glutamate receptor activity |
Cristina Casals |
UniProt |
| gomodel:66c7d41500000016 |
Trans-synaptic complex NRXN1B-CBLN1-GRID2 regulates synaptogenesis. (Human) |
production |
gomodel:66c7d41500000016/66c7d41500000017 |
GO:0098820 |
trans-synaptic protein complex |
GO:0030545 |
signaling receptor regulator activity |
Cristina Casals |
UniProt |
| gomodel:66c7d41500000544 |
CAAX-box protein maturation 1 (Mouse) |
production |
gomodel:66c7d41500000544/66c7d41500000580 |
GO:0005953 |
CAAX-protein geranylgeranyltransferase complex |
GO:0004662 |
CAAX-protein geranylgeranyltransferase activity |
David Hill |
MGI |
| gomodel:66c7d41500000616 |
CAAX-box protein maturation 2 (Mouse) |
production |
gomodel:66c7d41500000616/66c7d41500000644 |
GO:0005965 |
protein farnesyltransferase complex |
GO:0004660 |
protein farnesyltransferase activity |
David Hill |
MGI |
| gomodel:66c7d41500000672 |
NMDA glutamate receptor activity co-activated by glycine and involving GRIN1 and GRIN2B (Human) |
production |
gomodel:66c7d41500000672/66c7d41500000700 |
GO:0017146 |
NMDA selective glutamate receptor complex |
GO:0004972 |
NMDA glutamate receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:66c7d41500001120 |
NMDA glutamate receptor activity co-activated by glycine and involving GRIN1 and GRIN2C (Human) |
production |
gomodel:66c7d41500001120/66c7d41500001144 |
GO:0017146 |
NMDA selective glutamate receptor complex |
GO:0004972 |
NMDA glutamate receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:66c7d41500001389 |
Protein geranylgeranylation 1 (Mouse) |
production |
gomodel:66c7d41500001389/66c7d41500001410 |
GO:0005968 |
Rab-protein geranylgeranyltransferase complex |
GO:0004663 |
Rab geranylgeranyltransferase activity |
David Hill |
MGI |
| gomodel:66c7d41500001953 |
glycine-gated cation channel activity involving GRIN1 and GRIN3A (Human) |
production |
gomodel:66c7d41500001953/66c7d41500001975 |
GO:0098878 |
neurotransmitter receptor complex |
GO:0022824 |
transmitter-gated monoatomic ion channel activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:66c7d41500002843 |
Protein histidyl modification to diphthamide (Mouse) |
production |
gomodel:66c7d41500002843/66c7d41500002861 |
GO:0120513 |
2-(3-amino-3-carboxypropyl)histidine synthase complex |
GO:0090560 |
2-(3-amino-3-carboxypropyl)histidine synthase activity |
David Hill |
MGI |
| gomodel:66c7d41500002919 |
Heparan sulfate proteoglycan biosynthetic process (Dmel) |
production |
gomodel:66c7d41500002919/6792e70800000017 |
GO:0120504 |
EXT1-EXT2 complex |
GO:0050508 |
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity |
Rossana Zaru |
FlyBase |
| gomodel:66c7d41500002919 |
Heparan sulfate proteoglycan biosynthetic process (Dmel) |
production |
gomodel:66c7d41500002919/6792e70800000008 |
GO:0120504 |
EXT1-EXT2 complex |
GO:0050509 |
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity |
Rossana Zaru |
FlyBase |
| gomodel:66c7d41500003371 |
glycine-gated cation channel activity involving GRIN1 and GRIN3B (Human) |
production |
gomodel:66c7d41500003371/66c7d41500003391 |
GO:0098878 |
neurotransmitter receptor complex |
GO:0022824 |
transmitter-gated monoatomic ion channel activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:66c7d41500003458 |
NMDA glutamate receptor activity co-activated by glycine and involving GRIN1 and GRIN2D (Human) |
production |
gomodel:66c7d41500003458/66c7d41500003480 |
GO:0017146 |
NMDA selective glutamate receptor complex |
GO:0004972 |
NMDA glutamate receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:66e382fb00000049 |
NMDA glutamate receptor activity co-activated by D-serine and involving GRIN1 and GRIN2A (Human) |
production |
gomodel:66e382fb00000049/66e382fb00000094 |
GO:0017146 |
NMDA selective glutamate receptor complex |
GO:0004972 |
NMDA glutamate receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:66e382fb00000490 |
NEDD4L regulates ENaC (Human) |
production |
gomodel:66e382fb00000490/66e382fb00000524 |
GO:0034706 |
sodium channel complex |
GO:0005272 |
sodium channel activity |
Lionel Breuza |
UniProt |
| gomodel:66e382fb00001225 |
Protein sumoylation (Mouse) |
production |
gomodel:66e382fb00001225/66e382fb00001231 |
GO:0031510 |
SUMO activating enzyme complex |
GO:0019948 |
SUMO activating enzyme activity |
David Hill |
MGI |
| gomodel:66e382fb00001583 |
TRAF2 and OTUD7B regulate assembly and disassembly of mTORC1 and mTORC2 by mediating ubiquitination and deubiquitination of MLST8, respectively (Human). |
production |
gomodel:66e382fb00001583/66e382fb00001627 |
GO:0031931 |
TORC1 complex |
GO:0004674 |
protein serine/threonine kinase activity |
Sylvain Poux |
UniProt |
| gomodel:66e382fb00001583 |
TRAF2 and OTUD7B regulate assembly and disassembly of mTORC1 and mTORC2 by mediating ubiquitination and deubiquitination of MLST8, respectively (Human). |
production |
gomodel:66e382fb00001583/66e382fb00001614 |
GO:0031932 |
TORC2 complex |
GO:0004674 |
protein serine/threonine kinase activity |
Sylvain Poux |
UniProt |
| gomodel:66e382fb00001786 |
Hepcidin induction by BMP2/BMP6 complex signaling (Human) |
production |
gomodel:66e382fb00001786/66e382fb00001870 |
GO:0032991 |
protein-containing complex |
GO:0005125 |
cytokine activity |
Patrick Masson |
UniProt |
| gomodel:66f5faaa00000763 |
NSUN4 catalyzes RNA 5-methylcytosine mark on mitochondrial double-stranded RNAs, which are recognized by C1QBP, promoting RNA degradation by the mitochondrial degradosome complex (Human).
|
production |
gomodel:66f5faaa00000763/66f5faaa00000778 |
GO:0045025 |
mitochondrial degradosome |
GO:0000175 |
3'-5'-RNA exonuclease activity |
Sylvain Poux |
UniProt |
| gomodel:66f5faaa00001170 |
RVFV NSs-FBXO3 E3 ligase mediates TFIIH complex degradation. (Human) |
production |
gomodel:66f5faaa00001170/66f5faaa00001195 |
GO:0000439 |
transcription factor TFIIH core complex |
GO:0016251 |
RNA polymerase II general transcription initiation factor activity |
Cristina Casals |
UniProt |
| gomodel:66f5faaa00001204 |
Retinoid Metabolic Process 1 (Mouse) |
production |
gomodel:66f5faaa00001204/66f5faaa00001265 |
GO:0042627 |
chylomicron |
GO:0005501 |
retinoid binding |
David Hill |
MGI |
| gomodel:67086be200000251 |
pyruvate decarboxylation to acetyl-CoA (GO:0006086) |
production |
gomodel:67086be200000251/69d8496c00005581 |
GO:7770001 |
mitochondrial pyruvate carrier complex |
GO:0050833 |
pyruvate transmembrane transporter activity |
Val Wood |
PomBase |
| gomodel:67086be200000314 |
oxidative phosphorylation (Dmel) |
production |
gomodel:67086be200000314/67086be200000341 |
GO:0045271 |
respiratory chain complex I |
GO:0008137 |
NADH dehydrogenase (ubiquinone) activity |
Rossana Zaru |
FlyBase |
| gomodel:67086be200000314 |
oxidative phosphorylation (Dmel) |
production |
gomodel:67086be200000314/67086be200000392 |
GO:0045277 |
respiratory chain complex IV |
GO:0004129 |
cytochrome-c oxidase activity |
Rossana Zaru |
FlyBase |
| gomodel:67086be200000314 |
oxidative phosphorylation (Dmel) |
production |
gomodel:67086be200000314/67086be200000356 |
GO:0045275 |
respiratory chain complex III |
GO:0008121 |
quinol-cytochrome-c reductase activity |
Rossana Zaru |
FlyBase |
| gomodel:67086be200000314 |
oxidative phosphorylation (Dmel) |
production |
gomodel:67086be200000314/67086be200000334 |
GO:0045273 |
respiratory chain complex II (succinate dehydrogenase) |
GO:0008177 |
succinate dehydrogenase (quinone) activity |
Rossana Zaru |
FlyBase |
| gomodel:67086be200000314 |
oxidative phosphorylation (Dmel) |
production |
gomodel:67086be200000314/67086be200000436 |
GO:0045259 |
proton-transporting ATP synthase complex |
GO:0046933 |
proton-transporting ATP synthase activity, rotational mechanism |
Helen Attrill |
FlyBase |
| gomodel:67086be200000314 |
oxidative phosphorylation (Dmel) |
production |
gomodel:67086be200000314/67086be200000586 |
GO:0017133 |
mitochondrial electron transfer flavoprotein complex |
GO:0009055 |
electron transfer activity |
Helen Attrill |
FlyBase |
| gomodel:67086be200000519 |
mitochondrial translation (GO:0032543) |
production |
gomodel:67086be200000519/67c10cc400002410 |
GO:0005762 |
mitochondrial large ribosomal subunit |
GO:0030674 |
protein-macromolecule adaptor activity |
Val Wood |
PomBase |
| gomodel:67086be200000519 |
mitochondrial translation (GO:0032543) |
production |
gomodel:67086be200000519/67c10cc400002693 |
GO:0005762 |
mitochondrial large ribosomal subunit |
GO:0000048 |
peptidyltransferase activity |
Val Wood |
PomBase |
| gomodel:67086be200000519 |
mitochondrial translation (GO:0032543) |
production |
gomodel:67086be200000519/67e5e74400000451 |
GO:0180049 |
Mrh5C translation activator complex |
GO:0008494 |
translation activator activity |
Val Wood |
PomBase |
| gomodel:67086be200000519 |
mitochondrial translation (GO:0032543) |
production |
gomodel:67086be200000519/6796b94c00001311 |
GO:0005763 |
mitochondrial small ribosomal subunit |
GO:0003735 |
structural constituent of ribosome |
Val Wood |
PomBase |
| gomodel:67086be200000519 |
mitochondrial translation (GO:0032543) |
production |
gomodel:67086be200000519/684b6c8100000437 |
GO:0061671 |
Cbp3p-Cbp6 complex |
GO:0097177 |
mitochondrial ribosome binding |
Val Wood |
PomBase |
| gomodel:67086be200000519 |
mitochondrial translation (GO:0032543) |
production |
gomodel:67086be200000519/67c10cc400002391 |
GO:0180052 |
mitochondrial translation initiation complex |
GO:0030674 |
protein-macromolecule adaptor activity |
Val Wood |
PomBase |
| gomodel:67086be200000519 |
mitochondrial translation (GO:0032543) |
production |
gomodel:67086be200000519/67c10cc400002544 |
GO:0005763 |
mitochondrial small ribosomal subunit |
GO:0060090 |
molecular adaptor activity |
Val Wood |
PomBase |
| gomodel:67086be200002266 |
sphingolipid biosynthetic process (GO:0030148) |
production |
gomodel:67086be200002266/67c10cc400002302 |
GO:0017059 |
serine palmitoyltransferase complex |
GO:0004758 |
serine C-palmitoyltransferase activity |
Pascal Carme |
PomBase |
| gomodel:67086be200002705 |
Retinoid Metabolic Process 4 (Mouse) |
production |
gomodel:67086be200002705/67086be200002718 |
GO:0042627 |
chylomicron |
GO:0005501 |
retinoid binding |
David Hill |
MGI |
| gomodel:671ae02600000131 |
tricarboxylic acid cycle (Dmel) |
production |
gomodel:671ae02600000131/67c10cc400005736 |
GO:0009361 |
succinate-CoA ligase complex (ADP-forming) |
GO:0004774 |
succinate-CoA ligase activity |
Rossana Zaru |
FlyBase |
| gomodel:671ae02600000131 |
tricarboxylic acid cycle (Dmel) |
production |
gomodel:671ae02600000131/69d8496c00001325 |
GO:0045273 |
respiratory chain complex II (succinate dehydrogenase) |
GO:0008177 |
succinate dehydrogenase (quinone) activity |
Rossana Zaru |
FlyBase |
| gomodel:671ae02600000131 |
tricarboxylic acid cycle (Dmel) |
production |
gomodel:671ae02600000131/67c10cc400005749 |
GO:0045244 |
succinate-CoA ligase complex (GDP-forming) |
GO:0004774 |
succinate-CoA ligase activity |
Rossana Zaru |
FlyBase |
| gomodel:671ae02600003194 |
Negative regulation of cytokine production involved in inflammatory response via calcium influx by CHRNA7 homopentameric and PKC signaling in macrophages (Human). |
production |
gomodel:671ae02600003194/671ae02600003445 |
GO:0005942 |
phosphatidylinositol 3-kinase complex |
GO:0016303 |
1-phosphatidylinositol-3-kinase activity |
Cristina Casals |
UniProt |
| gomodel:67369e7600001439 |
(CHRNA7)3:(CHRNB2)2 acetylcholine receptor signaling pathway gated by amyloid beta complex, calcium transport. (Human) |
production |
gomodel:67369e7600001439/67369e7600001440 |
GO:0005892 |
acetylcholine-gated channel complex |
GO:0022848 |
acetylcholine-gated monoatomic cation-selective channel activity |
Cristina Casals |
UniProt |
| gomodel:67369e7600001439 |
(CHRNA7)3:(CHRNB2)2 acetylcholine receptor signaling pathway gated by amyloid beta complex, calcium transport. (Human) |
production |
gomodel:67369e7600001439/67369e7600001471 |
GO:0106003 |
amyloid-beta complex |
GO:0048018 |
receptor ligand activity |
Cristina Casals |
UniProt |
| gomodel:67369e7600002505 |
mitotic spindle assembly checkpoint signalling (GO:0007094) (ON) |
production |
gomodel:67369e7600002505/6a18a9ba00001592 |
GO:0005680 |
anaphase-promoting complex |
GO:0061630 |
ubiquitin protein ligase activity |
Val Wood |
PomBase |
| gomodel:67369e7600002505 |
mitotic spindle assembly checkpoint signalling (GO:0007094) (ON) |
production |
gomodel:67369e7600002505/6a18a9ba00001622 |
GO:0033597 |
mitotic checkpoint complex |
GO:0140678 |
molecular function inhibitor activity |
Val Wood |
PomBase |
| gomodel:67369e7600004023 |
ubiquinone biosynthetic process (Dmel)
|
production |
gomodel:67369e7600004023/67369e7600005084 |
GO:0032478 |
heterotetrameric polyprenyl diphosphate synthase complex |
GO:0120531 |
prenyl diphosphate synthase activity |
Helen Attrill |
FlyBase |
| gomodel:67369e7600005223 |
Regulation of appetite by (CHRNA3)3:(CHRNB4)2 nAChR activated by nicotine in POMC neurons. (Human) |
production |
gomodel:67369e7600005223/67369e7600005225 |
GO:0005892 |
acetylcholine-gated channel complex |
GO:0022848 |
acetylcholine-gated monoatomic cation-selective channel activity |
Cristina Casals |
UniProt |
| gomodel:67369e7600006071 |
Ubiquinone biosynthetic process 1 (Mouse) |
production |
gomodel:67369e7600006071/67369e7600006135 |
GO:0032991 |
protein-containing complex |
GO:0004659 |
prenyltransferase activity |
David Hill |
MGI |
| gomodel:678073a900001673 |
Inhibin A-mediated suppression of activin A signaling pathway (Human) |
production |
gomodel:678073a900001673/678073a900001719 |
GO:0043512 |
inhibin A complex |
GO:0140311 |
protein sequestering activity |
Patrick Masson |
UniProt |
| gomodel:678073a900001673 |
Inhibin A-mediated suppression of activin A signaling pathway (Human) |
production |
gomodel:678073a900001673/678073a900001681 |
GO:0043509 |
activin A complex |
GO:0005125 |
cytokine activity |
Patrick Masson |
UniProt |
| gomodel:678073a900002931 |
fatty acid biosynthetic process (GO:0006633) |
production |
gomodel:678073a900002931/678073a900003986 |
GO:0005835 |
fatty acid synthase complex |
GO:0004321 |
fatty-acyl-CoA synthase activity |
Pascal Carme |
PomBase |
| gomodel:678073a900003902 |
L-proline biosynthetic process (GO:0055129), L-proline catabolic process (GO:0006562), L-glutamine biosynthetic process (GO:1901704) |
production |
gomodel:678073a900003902/68b0f0d000003409 |
GO:0030956 |
glutamyl-tRNA(Gln) amidotransferase complex |
GO:0050567 |
glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity |
Val Wood |
PomBase |
| gomodel:6796b94c00000168 |
transcription elongation by RNA polymerase II (GO:0006368) (incomplete) |
production |
gomodel:6796b94c00000168/67b1629100002508 |
GO:0032044 |
DSIF complex |
GO:0003711 |
transcription elongation factor activity |
Val Wood |
PomBase |
| gomodel:6796b94c00000657 |
iron-sulfur cluster assembly (Dmel) |
production |
gomodel:6796b94c00000657/6796b94c00002385 |
GO:0120510 |
mitochondrial [4Fe-4S] assembly complex |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
Helen Attrill |
FlyBase |
| gomodel:6796b94c00000657 |
iron-sulfur cluster assembly (Dmel) |
production |
gomodel:6796b94c00000657/6796b94c00002397 |
GO:0120510 |
mitochondrial [4Fe-4S] assembly complex |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
Helen Attrill |
FlyBase |
| gomodel:6796b94c00000657 |
iron-sulfur cluster assembly (Dmel) |
production |
gomodel:6796b94c00000657/6796b94c00004196 |
GO:1904564 |
cytosolic [4Fe-4S] assembly scaffold complex |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
Helen Attrill |
FlyBase |
| gomodel:6796b94c00000657 |
iron-sulfur cluster assembly (Dmel) |
production |
gomodel:6796b94c00000657/6796b94c00004207 |
GO:0097361 |
cytosolic [4Fe-4S] assembly targeting complex |
GO:0140132 |
iron-sulfur cluster chaperone activity |
Helen Attrill |
FlyBase |
| gomodel:6796b94c00002252 |
Transcription-pause release by the PNUTS-PP1 complex (Human). |
production |
gomodel:6796b94c00002252/6796b94c00002262 |
GO:0032044 |
DSIF complex |
GO:0140870 |
RNA polymerase inhibitor activity |
Sylvain Poux |
UniProt |
| gomodel:6796b94c00002252 |
Transcription-pause release by the PNUTS-PP1 complex (Human). |
production |
gomodel:6796b94c00002252/6796b94c00002273 |
GO:0032021 |
NELF complex |
GO:0140870 |
RNA polymerase inhibitor activity |
Sylvain Poux |
UniProt |
| gomodel:6796b94c00002996 |
Leukocyte cell-cell adhesion mediated by ICAM1 receptor ligand and integrin ITGAL:ITGB2 complex receptor (HUMAN) |
production |
gomodel:6796b94c00002996/685de18700002169 |
GO:0034687 |
integrin alphaL-beta2 complex |
GO:0004895 |
cell adhesion receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:6796b94c00004884 |
Mo-molybdopterin cofactor biosynthetic process (Dmel) |
production |
gomodel:6796b94c00004884/6796b94c00004917 |
GO:1990140 |
molybdopterin synthase complex |
GO:0030366 |
molybdopterin synthase activity |
Helen Attrill |
FlyBase |
| gomodel:6796b94c00006848 |
TORC1 signaling (GO:0038202) |
production |
gomodel:6796b94c00006848/6796b94c00006918 |
GO:0061700 |
GATOR2 complex |
GO:0060089 |
molecular transducer activity |
Val Wood |
PomBase |
| gomodel:6796b94c00006848 |
TORC1 signaling (GO:0038202) |
production |
gomodel:6796b94c00006848/6796b94c00006868 |
GO:0033596 |
TSC1-TSC2 complex |
GO:0005096 |
GTPase activator activity |
Val Wood |
PomBase |
| gomodel:6796b94c00006848 |
TORC1 signaling (GO:0038202) |
production |
gomodel:6796b94c00006848/6796b94c00006896 |
GO:1990131 |
Gtr1-Gtr2 GTPase complex |
GO:0043539 |
protein serine/threonine kinase activator activity |
Val Wood |
PomBase |
| gomodel:6796b94c00006848 |
TORC1 signaling (GO:0038202) |
production |
gomodel:6796b94c00006848/6796b94c00006967 |
GO:1990877 |
FNIP-folliculin RagC/D GAP |
GO:0005096 |
GTPase activator activity |
Val Wood |
PomBase |
| gomodel:6796b94c00006848 |
TORC1 signaling (GO:0038202) |
production |
gomodel:6796b94c00006848/6796b94c00006934 |
GO:0071986 |
Ragulator complex |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
Val Wood |
PomBase |
| gomodel:6796b94c00006848 |
TORC1 signaling (GO:0038202) |
production |
gomodel:6796b94c00006848/6796b94c00006907 |
GO:1990130 |
GATOR1 complex |
GO:0005096 |
GTPase activator activity |
Val Wood |
PomBase |
| gomodel:6796b94c00006848 |
TORC1 signaling (GO:0038202) |
production |
gomodel:6796b94c00006848/6796b94c00006849 |
GO:0031931 |
TORC1 complex |
GO:0004674 |
protein serine/threonine kinase activity |
Val Wood |
PomBase |
| gomodel:67b1629100002705 |
Activin A signaling pathway (Human) |
production |
gomodel:67b1629100002705/67b1629100002713 |
GO:0043509 |
activin A complex |
GO:0005125 |
cytokine activity |
Patrick Masson |
UniProt |
| gomodel:67b1629100003158 |
RAB39A and RAB2A-induced HOPS-mediated autophagosome-lysosome fusion (Human) |
production |
gomodel:67b1629100003158/67b1629100003195 |
GO:0030897 |
HOPS complex |
GO:0060090 |
molecular adaptor activity |
Lucille Pourcel |
UniProt |
| gomodel:67b1629100003856 |
ARMC5 mediates RNA polymerase II transcription initiation surveillance by mediating ubiquitination and degradation of POLR2A (Human). |
production |
gomodel:67b1629100003856/67b1629100004259 |
GO:0032044 |
DSIF complex |
GO:0140870 |
RNA polymerase inhibitor activity |
Sylvain Poux |
UniProt |
| gomodel:67b1629100003856 |
ARMC5 mediates RNA polymerase II transcription initiation surveillance by mediating ubiquitination and degradation of POLR2A (Human). |
production |
gomodel:67b1629100003856/67b1629100004271 |
GO:0032021 |
NELF complex |
GO:0140870 |
RNA polymerase inhibitor activity |
Sylvain Poux |
UniProt |
| gomodel:67b1629100004023 |
The INTAC complex mediates RNA polymerase II transcription initiation surveillance by catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit POLR2A and degrading the exiting nascent RNA transcript (Human). |
production |
gomodel:67b1629100004023/67b1629100004182 |
GO:0032044 |
DSIF complex |
GO:0140870 |
RNA polymerase inhibitor activity |
Sylvain Poux |
UniProt |
| gomodel:67b1629100004023 |
The INTAC complex mediates RNA polymerase II transcription initiation surveillance by catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit POLR2A and degrading the exiting nascent RNA transcript (Human). |
production |
gomodel:67b1629100004023/67b1629100004193 |
GO:0032021 |
NELF complex |
GO:0140870 |
RNA polymerase inhibitor activity |
Sylvain Poux |
UniProt |
| gomodel:67c10cc400000238 |
'de novo' cotranslational protein folding (GO:0051083) |
production |
gomodel:67c10cc400000238/67c10cc400000239 |
GO:0110078 |
TTT Hsp90 cochaperone complex |
GO:0030674 |
protein-macromolecule adaptor activity |
Val Wood |
PomBase |
| gomodel:67c10cc400005671 |
The classical complement pathway (Human). |
production |
gomodel:67c10cc400005671/67c10cc400005695 |
GO:0062167 |
complement component C1q complex |
GO:0019864 |
IgG binding |
Sylvain Poux |
UniProt |
| gomodel:67c10cc400005671 |
The classical complement pathway (Human). |
production |
gomodel:67c10cc400005671/67c10cc400008203 |
GO:0005579 |
membrane attack complex |
GO:0022829 |
wide pore channel activity |
Sylvain Poux |
UniProt |
| gomodel:67c10cc400008763 |
CD59 inhibits formation of the membrane attack complex, protecting self-cells (Human). |
production |
gomodel:67c10cc400008763/67c10cc400008873 |
GO:0005579 |
membrane attack complex |
GO:0022829 |
wide pore channel activity |
Sylvain Poux |
UniProt |
| gomodel:67c10cc400009046 |
Clusterin (CLU) inhibits formation of the membrane attack complex (Human). |
production |
gomodel:67c10cc400009046/67c10cc400009047 |
GO:0005579 |
membrane attack complex |
GO:0022829 |
wide pore channel activity |
Sylvain Poux |
UniProt |
| gomodel:67e5e74400000671 |
The lectin complement pathway following activation by MBL2 lectin (Human). |
production |
gomodel:67e5e74400000671/67e5e74400000781 |
GO:0005579 |
membrane attack complex |
GO:0022829 |
wide pore channel activity |
Sylvain Poux |
UniProt |
| gomodel:67e5e74400000919 |
The lectin complement pathway following activation by FCN1 lectin (Human). |
production |
gomodel:67e5e74400000919/67e5e74400000966 |
GO:0005579 |
membrane attack complex |
GO:0022829 |
wide pore channel activity |
Sylvain Poux |
UniProt |
| gomodel:67e5e74400001094 |
The lectin complement pathway following activation by FCN2 lectin (Human). |
production |
gomodel:67e5e74400001094/67e5e74400001141 |
GO:0005579 |
membrane attack complex |
GO:0022829 |
wide pore channel activity |
Sylvain Poux |
UniProt |
| gomodel:67e5e74400001269 |
The lectin complement pathway following activation by FCN3 lectin (Human). |
production |
gomodel:67e5e74400001269/67e5e74400001316 |
GO:0005579 |
membrane attack complex |
GO:0022829 |
wide pore channel activity |
Sylvain Poux |
UniProt |
| gomodel:67e5e74400001614 |
The alternative complement pathway (Human). |
production |
gomodel:67e5e74400001614/67e5e74400001724 |
GO:0005579 |
membrane attack complex |
GO:0022829 |
wide pore channel activity |
Sylvain Poux |
UniProt |
| gomodel:67e5e74400001888 |
The GZMK complement pathway (Human). |
production |
gomodel:67e5e74400001888/67e5e74400001998 |
GO:0005579 |
membrane attack complex |
GO:0022829 |
wide pore channel activity |
Sylvain Poux |
UniProt |
| gomodel:67e5e74400003073 |
mitochondrial cytochrome c oxidase assembly (GO:0033617) |
production |
gomodel:67e5e74400003073/67e5e74400003109 |
GO:0045277 |
respiratory chain complex IV |
GO:0004129 |
cytochrome-c oxidase activity |
Val Wood |
PomBase |
| gomodel:67e5e74400004366 |
tRNA modification (GO:0006400) (nuclear/cytosolic) |
production |
gomodel:67e5e74400004366/67e5e74400004403 |
GO:0033588 |
elongator holoenzyme complex |
GO:0106261 |
tRNA uridine(34) acetyltransferase activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00000199 |
protein insertion into ER membrane (GO:0045048), post-translational targeting to endoplasmic reticulum membrane (GO:0006620) PLUS import into Lumen (No term) and target proteins |
production |
gomodel:67f85f2b00000199/67f85f2b00000286 |
GO:0160005 |
PAT complex |
GO:0044183 |
protein folding chaperone |
Val Wood |
PomBase |
| gomodel:67f85f2b00000199 |
protein insertion into ER membrane (GO:0045048), post-translational targeting to endoplasmic reticulum membrane (GO:0006620) PLUS import into Lumen (No term) and target proteins |
production |
gomodel:67f85f2b00000199/67f85f2b00000304 |
GO:0005786 |
signal recognition particle, endoplasmic reticulum targeting |
GO:0030942 |
endoplasmic reticulum signal sequence receptor activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00000199 |
protein insertion into ER membrane (GO:0045048), post-translational targeting to endoplasmic reticulum membrane (GO:0006620) PLUS import into Lumen (No term) and target proteins |
production |
gomodel:67f85f2b00000199/67f85f2b00000275 |
GO:0005784 |
Sec61 translocon complex |
GO:0008320 |
transmembrane protein transporter activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00000199 |
protein insertion into ER membrane (GO:0045048), post-translational targeting to endoplasmic reticulum membrane (GO:0006620) PLUS import into Lumen (No term) and target proteins |
production |
gomodel:67f85f2b00000199/67f85f2b00000223 |
GO:0043529 |
GET complex |
GO:0032977 |
membrane insertase activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00000199 |
protein insertion into ER membrane (GO:0045048), post-translational targeting to endoplasmic reticulum membrane (GO:0006620) PLUS import into Lumen (No term) and target proteins |
production |
gomodel:67f85f2b00000199/67f85f2b00000510 |
GO:0005785 |
signal recognition particle receptor complex |
GO:0060090 |
molecular adaptor activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00000199 |
protein insertion into ER membrane (GO:0045048), post-translational targeting to endoplasmic reticulum membrane (GO:0006620) PLUS import into Lumen (No term) and target proteins |
production |
gomodel:67f85f2b00000199/67f85f2b00001802 |
GO:0005784 |
Sec61 translocon complex |
GO:0008320 |
transmembrane protein transporter activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00000199 |
protein insertion into ER membrane (GO:0045048), post-translational targeting to endoplasmic reticulum membrane (GO:0006620) PLUS import into Lumen (No term) and target proteins |
production |
gomodel:67f85f2b00000199/67f85f2b00000538 |
GO:0031207 |
Sec62/Sec63 complex |
GO:0140597 |
protein carrier activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00000199 |
protein insertion into ER membrane (GO:0045048), post-translational targeting to endoplasmic reticulum membrane (GO:0006620) PLUS import into Lumen (No term) and target proteins |
production |
gomodel:67f85f2b00000199/67f85f2b00000249 |
GO:0072380 |
TRC complex |
GO:0140597 |
protein carrier activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00000199 |
protein insertion into ER membrane (GO:0045048), post-translational targeting to endoplasmic reticulum membrane (GO:0006620) PLUS import into Lumen (No term) and target proteins |
production |
gomodel:67f85f2b00000199/67f85f2b00000200 |
GO:0072546 |
EMC complex |
GO:0032977 |
membrane insertase activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00000199 |
protein insertion into ER membrane (GO:0045048), post-translational targeting to endoplasmic reticulum membrane (GO:0006620) PLUS import into Lumen (No term) and target proteins |
production |
gomodel:67f85f2b00000199/67f85f2b00000527 |
GO:0005787 |
signal peptidase complex |
GO:0004252 |
serine-type endopeptidase activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00001360 |
proteasome assembly (GO:0043248) |
production |
gomodel:67f85f2b00001360/67f85f2b00001361 |
GO:0005839 |
proteasome core complex |
GO:0008233 |
peptidase activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00001360 |
proteasome assembly (GO:0043248) |
production |
gomodel:67f85f2b00001360/67f85f2b00001390 |
GO:0008541 |
proteasome regulatory particle, lid subcomplex |
GO:0140492 |
metal-dependent deubiquitinase activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00001360 |
proteasome assembly (GO:0043248) |
production |
gomodel:67f85f2b00001360/67f85f2b00001378 |
GO:0008540 |
proteasome regulatory particle, base subcomplex |
GO:0036402 |
proteasome-activating activity |
Val Wood |
PomBase |
| gomodel:67f85f2b00002096 |
mitotic actomyosin contractile ring assembly (GO:1903475) |
production |
gomodel:67f85f2b00002096/67f85f2b00002245 |
GO:0008290 |
F-actin capping protein complex |
GO:0051015 |
actin filament binding |
Val Wood |
PomBase |
| gomodel:67f85f2b00002506 |
mitochondrial proton-transporting ATP synthase complex assembly (GO:0033615) |
production |
gomodel:67f85f2b00002506/67f85f2b00002565 |
GO:0045259 |
proton-transporting ATP synthase complex |
GO:0046933 |
proton-transporting ATP synthase activity, rotational mechanism |
Val Wood |
PomBase |
| gomodel:67f85f2b00003383 |
mitochondrial respiratory chain complex II assembly (GO:0034553) |
production |
gomodel:67f85f2b00003383/67f85f2b00003546 |
GO:0045273 |
respiratory chain complex II (succinate dehydrogenase) |
GO:0009055 |
electron transfer activity |
Val Wood |
PomBase |
| gomodel:680ad14200000983 |
TNRC18 mediates silencing of endogenous retroviruses (ERV) by binding to H3K9me3 and mediating recruitment of Sin3-type complexes (Human). |
production |
gomodel:680ad14200000983/680ad14200001022 |
GO:0070822 |
Sin3-type complex |
GO:0004407 |
histone deacetylase activity |
Sylvain Poux |
UniProt |
| gomodel:680ad14200002460 |
Xenobiotic detoxification enabled by efflux pump complex mexAB-OprM (P. aeruginosa PA01) |
production |
gomodel:680ad14200002460/69c59f8a00001100 |
GO:1990281 |
efflux pump complex |
GO:0015562 |
efflux transmembrane transporter activity |
Paul Denny |
UniProt |
| gomodel:680ad14200002972 |
GPR35-mediated signaling via G-alpha-i (inhibitory), inhibiting adenylate cyclase promotes cardioprotection during ischemia following activation by kynurenic acid (Human). |
production |
gomodel:680ad14200002972/680ad14200003021 |
GO:0045259 |
proton-transporting ATP synthase complex |
GO:0046933 |
proton-transporting ATP synthase activity, rotational mechanism |
Sylvain Poux |
UniProt |
| gomodel:680ad14200005355 |
PS/PtdIns4P exchange by OSBPL9/OSBPL11 in the ER-trans Gogi membrane contact site (Human) |
production |
gomodel:680ad14200005355/680ad14200005356 |
GO:7770015 |
intermembrane lipid transporter complex |
GO:0160270 |
phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity |
Vitalina Kharchenko |
University of Osnabrueck Molecular Cell Biology Division |
| gomodel:682fbcd000002112 |
SRCAP acts as transcription coactivator in cAMP/PKA signal transduction. (Human) |
production |
gomodel:682fbcd000002112/682fbcd000002120 |
GO:0005952 |
cAMP-dependent protein kinase complex |
GO:0004691 |
cAMP-dependent protein kinase activity |
Cristina Casals |
UniProt |
| gomodel:682fbcd000003101 |
PRDM16 acts as a key chromatin adapter that mediates differentiation of brown adipocytes (Human). |
production |
gomodel:682fbcd000003101/682fbcd000003153 |
GO:0016592 |
mediator complex |
GO:0003713 |
transcription coactivator activity |
Sylvain Poux |
UniProt |
| gomodel:682fbcd000003781 |
OSBPL1A sensor for cholesterol transport between late endosome/lysosome and ER (Human) |
production |
gomodel:682fbcd000003781/6870555700003071 |
GO:0032991 |
protein-containing complex |
GO:0060090 |
molecular adaptor activity |
Vitalina Kharchenko |
University of Osnabrueck Molecular Cell Biology Division |
| gomodel:682fbcd000004233 |
PS/PI4P exchange via OSBP5/8 regulates cholesterol transport via GRAMD1B (Human) |
production |
gomodel:682fbcd000004233/682fbcd000004265 |
GO:7770015 |
intermembrane lipid transporter complex |
GO:0160270 |
phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity |
Vitalina Kharchenko |
University of Osnabrueck Molecular Cell Biology Division |
| gomodel:682fbcd000004638 |
BCAT2 provides acetyl-CoA upstream of EP300, leading to acetylation and inhibition of PRDM16 (Human). |
production |
gomodel:682fbcd000004638/682fbcd000004688 |
GO:0016592 |
mediator complex |
GO:0003713 |
transcription coactivator activity |
Sylvain Poux |
UniProt |
| gomodel:682fbcd000004750 |
TLE3 acts as a chromatin adapter that mediates differentiation of white adipocytes and prevents browning of adipocytes (Human). |
production |
gomodel:682fbcd000004750/682fbcd000004800 |
GO:0016592 |
mediator complex |
GO:0003713 |
transcription coactivator activity |
Sylvain Poux |
UniProt |
| gomodel:682fbcd000006558 |
cristae formation (GO:0042407) |
production |
gomodel:682fbcd000006558/682fbcd000006587 |
GO:0061617 |
MICOS complex |
GO:0043495 |
protein-membrane adaptor activity |
Val Wood |
PomBase |
| gomodel:684b6c8100001669 |
Canonical Glycolysis (Human) |
production |
gomodel:684b6c8100001669/684b6c8100001747 |
GO:0005945 |
6-phosphofructokinase complex |
GO:0003872 |
6-phosphofructokinase activity |
Lucille Pourcel |
UniProt |
| gomodel:685de18700000512 |
mitochondrial tRNA U34 taurinomethyluridine modifications (Dmel) |
production |
gomodel:685de18700000512/685de18700006904 |
GO:7770010 |
GTPBP3-MTO1 complex |
GO:0160236 |
tRNA 5-taurinomethyluridine synthase activity |
Helen Attrill |
FlyBase |
| gomodel:685de18700000512 |
mitochondrial tRNA U34 taurinomethyluridine modifications (Dmel) |
production |
gomodel:685de18700000512/685de18700001010 |
GO:7770010 |
GTPBP3-MTO1 complex |
GO:0160236 |
tRNA 5-taurinomethyluridine synthase activity |
Helen Attrill |
FlyBase |
| gomodel:685de18700000512 |
mitochondrial tRNA U34 taurinomethyluridine modifications (Dmel) |
production |
gomodel:685de18700000512/685de18700007243 |
GO:7770010 |
GTPBP3-MTO1 complex |
GO:0160236 |
tRNA 5-taurinomethyluridine synthase activity |
Helen Attrill |
FlyBase |
| gomodel:685de18700000512 |
mitochondrial tRNA U34 taurinomethyluridine modifications (Dmel) |
production |
gomodel:685de18700000512/685de18700006861 |
GO:7770010 |
GTPBP3-MTO1 complex |
GO:0160236 |
tRNA 5-taurinomethyluridine synthase activity |
Helen Attrill |
FlyBase |
| gomodel:685de18700002961 |
T cell receptor signaling (Human). |
production |
gomodel:685de18700002961/685de18700002981 |
GO:0042613 |
MHC class II protein complex |
GO:0042605 |
peptide antigen binding |
Sylvain Poux |
UniProt |
| gomodel:685de18700002961 |
T cell receptor signaling (Human). |
production |
gomodel:685de18700002961/685de18700002962 |
GO:0042105 |
alpha-beta T cell receptor complex |
GO:0032395 |
MHC class II receptor activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700003080 |
Leukocyte cell-cell adhesion mediated by ICAM2 receptor ligand and integrin ITGAL:ITGB2 complex receptor (HUMAN) |
production |
gomodel:685de18700003080/685de18700003086 |
GO:0034687 |
integrin alphaL-beta2 complex |
GO:0004895 |
cell adhesion receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:685de18700003315 |
Stimulation ot T cell receptor signaling by CD28 following binding to CD80 (Human). |
production |
gomodel:685de18700003315/685de18700003316 |
GO:0042105 |
alpha-beta T cell receptor complex |
GO:0032395 |
MHC class II receptor activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700003315 |
Stimulation ot T cell receptor signaling by CD28 following binding to CD80 (Human). |
production |
gomodel:685de18700003315/685de18700003335 |
GO:0042613 |
MHC class II protein complex |
GO:0042605 |
peptide antigen binding |
Sylvain Poux |
UniProt |
| gomodel:685de18700003492 |
Stimulation ot T cell receptor signaling by CD28 following binding to CD86 (Human). |
production |
gomodel:685de18700003492/685de18700003512 |
GO:0042613 |
MHC class II protein complex |
GO:0042605 |
peptide antigen binding |
Sylvain Poux |
UniProt |
| gomodel:685de18700003492 |
Stimulation ot T cell receptor signaling by CD28 following binding to CD86 (Human). |
production |
gomodel:685de18700003492/685de18700003493 |
GO:0042105 |
alpha-beta T cell receptor complex |
GO:0032395 |
MHC class II receptor activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700003890 |
CTLA4 inhibits T-cell activation by acting as a decoy receptor for CD80 (Human). |
production |
gomodel:685de18700003890/685de18700003891 |
GO:0042105 |
alpha-beta T cell receptor complex |
GO:0032395 |
MHC class II receptor activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700003890 |
CTLA4 inhibits T-cell activation by acting as a decoy receptor for CD80 (Human). |
production |
gomodel:685de18700003890/685de18700003910 |
GO:0042613 |
MHC class II protein complex |
GO:0042605 |
peptide antigen binding |
Sylvain Poux |
UniProt |
| gomodel:685de18700004045 |
CTLA4 inhibits T-cell activation by acting as a decoy receptor for CD86 (Human). |
production |
gomodel:685de18700004045/685de18700004046 |
GO:0042105 |
alpha-beta T cell receptor complex |
GO:0032395 |
MHC class II receptor activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700004045 |
CTLA4 inhibits T-cell activation by acting as a decoy receptor for CD86 (Human). |
production |
gomodel:685de18700004045/685de18700004065 |
GO:0042613 |
MHC class II protein complex |
GO:0042605 |
peptide antigen binding |
Sylvain Poux |
UniProt |
| gomodel:685de18700004252 |
CERS2 galactosylceramide synthesis (Human) |
production |
gomodel:685de18700004252/685de18700004253 |
GO:0017059 |
serine palmitoyltransferase complex |
GO:0004758 |
serine C-palmitoyltransferase activity |
Vitalina Kharchenko |
University of Osnabrueck Molecular Cell Biology Division |
| gomodel:685de18700004471 |
Activation of PDCD1/PD-1 by CD274 inhibits T-cell activation by promoting recruitment of PTPN11, leading to dephosphorylation of key TCR signaling molecules (Human). |
production |
gomodel:685de18700004471/685de18700004491 |
GO:0042613 |
MHC class II protein complex |
GO:0042605 |
peptide antigen binding |
Sylvain Poux |
UniProt |
| gomodel:685de18700004471 |
Activation of PDCD1/PD-1 by CD274 inhibits T-cell activation by promoting recruitment of PTPN11, leading to dephosphorylation of key TCR signaling molecules (Human). |
production |
gomodel:685de18700004471/685de18700004472 |
GO:0042105 |
alpha-beta T cell receptor complex |
GO:0032395 |
MHC class II receptor activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700004682 |
Activation of PDCD1/PD-1 by PDCD1LG2 inhibits T-cell activation by promoting recruitment of PTPN11, leading to dephosphorylation of key TCR signaling molecules (Human). |
production |
gomodel:685de18700004682/685de18700004683 |
GO:0042105 |
alpha-beta T cell receptor complex |
GO:0032395 |
MHC class II receptor activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700004682 |
Activation of PDCD1/PD-1 by PDCD1LG2 inhibits T-cell activation by promoting recruitment of PTPN11, leading to dephosphorylation of key TCR signaling molecules (Human). |
production |
gomodel:685de18700004682/685de18700004702 |
GO:0042613 |
MHC class II protein complex |
GO:0042605 |
peptide antigen binding |
Sylvain Poux |
UniProt |
| gomodel:685de18700004975 |
Xenobiotic detoxification enabled by EmrAB-TolC complex (E.coli) |
production |
gomodel:685de18700004975/685de18700004976 |
GO:1990281 |
efflux pump complex |
GO:0015562 |
efflux transmembrane transporter activity |
Paul Denny |
UniProt |
| gomodel:685de18700005035 |
Leukocyte cell-cell adhesion mediated by ICAM3 receptor ligand and integrin ITGAL:ITGB2 complex receptor (HUMAN) |
production |
gomodel:685de18700005035/685de18700005041 |
GO:0034687 |
integrin alphaL-beta2 complex |
GO:0004895 |
cell adhesion receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:685de18700005103 |
Leukocyte cell-cell adhesion mediated by ICAM3 receptor ligand and integrin ITGAD:ITGB2 complex receptor (HUMAN) |
production |
gomodel:685de18700005103/685de18700005109 |
GO:0034690 |
integrin alphaD-beta2 complex |
GO:0004895 |
cell adhesion receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:685de18700005171 |
Inhibition of T cell receptor signaling by LAG3 following binding to MHC class II and ubiquitination by CBL (Human). |
production |
gomodel:685de18700005171/685de18700005191 |
GO:0042613 |
MHC class II protein complex |
GO:0042605 |
peptide antigen binding |
Sylvain Poux |
UniProt |
| gomodel:685de18700005171 |
Inhibition of T cell receptor signaling by LAG3 following binding to MHC class II and ubiquitination by CBL (Human). |
production |
gomodel:685de18700005171/685de18700005303 |
GO:0042613 |
MHC class II protein complex |
GO:0048018 |
receptor ligand activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700005171 |
Inhibition of T cell receptor signaling by LAG3 following binding to MHC class II and ubiquitination by CBL (Human). |
production |
gomodel:685de18700005171/685de18700005172 |
GO:0042105 |
alpha-beta T cell receptor complex |
GO:0032395 |
MHC class II receptor activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700005414 |
Inhibition of T cell receptor signaling by LAG3 following binding to MHC class II and ubiquitination by CBLB (Human). |
production |
gomodel:685de18700005414/685de18700005434 |
GO:0042613 |
MHC class II protein complex |
GO:0042605 |
peptide antigen binding |
Sylvain Poux |
UniProt |
| gomodel:685de18700005414 |
Inhibition of T cell receptor signaling by LAG3 following binding to MHC class II and ubiquitination by CBLB (Human). |
production |
gomodel:685de18700005414/685de18700005497 |
GO:0042613 |
MHC class II protein complex |
GO:0048018 |
receptor ligand activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700005414 |
Inhibition of T cell receptor signaling by LAG3 following binding to MHC class II and ubiquitination by CBLB (Human). |
production |
gomodel:685de18700005414/685de18700005415 |
GO:0042105 |
alpha-beta T cell receptor complex |
GO:0032395 |
MHC class II receptor activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700005545 |
Inhibition of T cell receptor signaling by LAG3 following binding to FGL1 and ubiquitination by CBL (Human). |
production |
gomodel:685de18700005545/685de18700005565 |
GO:0042613 |
MHC class II protein complex |
GO:0042605 |
peptide antigen binding |
Sylvain Poux |
UniProt |
| gomodel:685de18700005545 |
Inhibition of T cell receptor signaling by LAG3 following binding to FGL1 and ubiquitination by CBL (Human). |
production |
gomodel:685de18700005545/685de18700005546 |
GO:0042105 |
alpha-beta T cell receptor complex |
GO:0032395 |
MHC class II receptor activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700005690 |
Inhibition of T cell receptor signaling by LAG3 following binding to FGL1 and ubiquitination by CBLB (Human). |
production |
gomodel:685de18700005690/685de18700005691 |
GO:0042105 |
alpha-beta T cell receptor complex |
GO:0032395 |
MHC class II receptor activity |
Sylvain Poux |
UniProt |
| gomodel:685de18700005690 |
Inhibition of T cell receptor signaling by LAG3 following binding to FGL1 and ubiquitination by CBLB (Human). |
production |
gomodel:685de18700005690/685de18700005710 |
GO:0042613 |
MHC class II protein complex |
GO:0042605 |
peptide antigen binding |
Sylvain Poux |
UniProt |
| gomodel:685de18700006487 |
Leukocyte adhesion to vascular endothelial cell mediated by ICAM1 receptor ligand and integrin ITGAM:ITGB2 complex receptor (HUMAN) |
production |
gomodel:685de18700006487/685de18700006498 |
GO:0034688 |
integrin alphaM-beta2 complex |
GO:0004895 |
cell adhesion receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:685de18700006767 |
phospholipid transport (GO:0015914) (ER/mitochondrion) |
production |
gomodel:685de18700006767/685de18700006845 |
GO:0032865 |
ERMES complex |
GO:1990050 |
phosphatidic acid transfer activity |
Val Wood |
PomBase |
| gomodel:685de18700007362 |
Erythrocyte phagocytosis mediated by ICAM4 receptor ligand and integrin ITGAX:ITGB2 complex receptor (HUMAN) |
production |
gomodel:685de18700007362/685de18700007372 |
GO:0034689 |
integrin alphaX-beta2 complex |
GO:0004895 |
cell adhesion receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:685de18700007400 |
mitochondrial translation (Dmel) |
production |
gomodel:685de18700007400/685de18700007497 |
GO:0180052 |
mitochondrial translation initiation complex |
GO:1990856 |
methionyl-initiator methionine tRNA binding |
Helen Attrill |
FlyBase |
| gomodel:685de18700007400 |
mitochondrial translation (Dmel) |
production |
gomodel:685de18700007400/6870555700000240 |
GO:0180052 |
mitochondrial translation initiation complex |
GO:0003729 |
mRNA binding |
Helen Attrill |
FlyBase |
| gomodel:685de18700007400 |
mitochondrial translation (Dmel) |
production |
gomodel:685de18700007400/685de18700007493 |
GO:0005762 |
mitochondrial large ribosomal subunit |
GO:0003735 |
structural constituent of ribosome |
Helen Attrill |
FlyBase |
| gomodel:685de18700007400 |
mitochondrial translation (Dmel) |
production |
gomodel:685de18700007400/685de18700007401 |
GO:0005763 |
mitochondrial small ribosomal subunit |
GO:0003735 |
structural constituent of ribosome |
Helen Attrill |
FlyBase |
| gomodel:6870555700000202 |
Erythrocyte cell-platelet cell adhesion mediated by ICAM4 receptor ligand and integrin ITGA2B:ITGB3 complex receptor (HUMAN) |
production |
gomodel:6870555700000202/6870555700000211 |
GO:0070442 |
integrin alphaIIb-beta3 complex |
GO:0004895 |
cell adhesion receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:6870555700000320 |
Xenobiotic detoxification enabled by efflux complex AcrABZ-TolC (E.coli) |
production |
gomodel:6870555700000320/69c59f8a00001058 |
GO:1990281 |
efflux pump complex |
GO:0015562 |
efflux transmembrane transporter activity |
Paul Denny |
UniProt |
| gomodel:6870555700000578 |
PS/PtdIns4P exchange by OSBPL9/OSBPL10 in ER-TGN membrane contact site (Human) |
production |
gomodel:6870555700000578/6870555700000583 |
GO:7770015 |
intermembrane lipid transporter complex |
GO:0160270 |
phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity |
Vitalina Kharchenko |
University of Osnabrueck Molecular Cell Biology Division |
| gomodel:6870555700001180 |
Laminin-1 binding to alpha-dystroglycan increases agrin-induced acetylcholine receptor aggregation (Human) |
production |
gomodel:6870555700001180/6870555700004098 |
GO:0005606 |
laminin-111 trimer |
GO:0048018 |
receptor ligand activity |
Livia Famiglietti |
UniProt |
| gomodel:6882d2b800001018 |
ASGR1-mediated recycling of N-acetylgalactosamine-units (Human) |
production |
gomodel:6882d2b800001018/6882d2b800001061 |
GO:0030122 |
AP-2 adaptor complex |
GO:0035615 |
clathrin-cargo adaptor activity |
Patrick Masson |
UniProt |
| gomodel:6882d2b800002705 |
Dolichyl phosphate biosynthesis (Dmel) |
production |
gomodel:6882d2b800002705/6882d2b800002706 |
GO:1904423 |
dehydrodolichyl diphosphate synthase complex |
GO:0045547 |
ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity |
Rossana Zaru |
FlyBase |
| gomodel:689e7a5d00000225 |
Neuron cell-leukocyte adhesion mediated by ICAM5 receptor ligand and integrin ITGAL:ITGB2 complex receptor (HUMAN) |
production |
gomodel:689e7a5d00000225/689e7a5d00000231 |
GO:0034687 |
integrin alphaL-beta2 complex |
GO:0004895 |
cell adhesion receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:689e7a5d00000567 |
Activation of XBP1 by IRE1 in UPR (Human) |
production |
gomodel:689e7a5d00000567/689e7a5d00000627 |
GO:1902494 |
catalytic complex |
GO:0044600 |
protein guanylyltransferase activity |
Lionel Breuza |
UniProt |
| gomodel:689e7a5d00003220 |
mitochondrial tRNA modification (GO:0070900 ) glutamic acid (glutamate) and glutamine |
production |
gomodel:689e7a5d00003220/689e7a5d00003311 |
GO:0030956 |
glutamyl-tRNA(Gln) amidotransferase complex |
GO:0050567 |
glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity |
Val Wood |
PomBase |
| gomodel:689e7a5d00003489 |
FBXO44-mediated degradation of RGS2 via CUL4B/DDB1 complex (Human) |
production |
gomodel:689e7a5d00003489/689e7a5d00004189 |
GO:0032991 |
protein-containing complex |
GO:0160072 |
ubiquitin ligase complex scaffold activity |
Patrick Masson |
UniProt |
| gomodel:689e7a5d00004061 |
Regulation of Respiratory chain complex I by COXFA4L2 upon hypoxia. (Human) |
production |
gomodel:689e7a5d00004061/689e7a5d00004278 |
GO:0045271 |
respiratory chain complex I |
GO:0008137 |
NADH dehydrogenase (ubiquinone) activity |
Cristina Casals |
UniProt |
| gomodel:689e7a5d00004320 |
Lactate regulates dendritic cell function trhough ROS production inhibition by COXFA4L2. (Mouse) |
production |
gomodel:689e7a5d00004320/689e7a5d00004344 |
GO:0045271 |
respiratory chain complex I |
GO:0008137 |
NADH dehydrogenase (ubiquinone) activity |
Cristina Casals |
UniProt |
| gomodel:689e7a5d00004412 |
Lactate regulates dendritic cell function trhough ROS production inhibition by COXFA4L2. (Human) |
production |
gomodel:689e7a5d00004412/689e7a5d00004425 |
GO:0045271 |
respiratory chain complex I |
GO:0008137 |
NADH dehydrogenase (ubiquinone) activity |
Cristina Casals |
UniProt |
| gomodel:68b0f0d000001211 |
De novo sphingomyelin biosynthesis (CerS1) |
production |
gomodel:68b0f0d000001211/68b0f0d000001212 |
GO:0017059 |
serine palmitoyltransferase complex |
GO:0004758 |
serine C-palmitoyltransferase activity |
Vitalina Kharchenko |
University of Osnabrueck Molecular Cell Biology Division |
| gomodel:68b0f0d000004290 |
De novo sphingomyelin synthesis (Human) CerS5 |
production |
gomodel:68b0f0d000004290/68b0f0d000004297 |
GO:0017059 |
serine palmitoyltransferase complex |
GO:0004758 |
serine C-palmitoyltransferase activity |
Vitalina Kharchenko |
University of Osnabrueck Molecular Cell Biology Division |
| gomodel:68b0f0d000005568 |
De novo sphingomyelin synthesis (Human) CerS4 |
production |
gomodel:68b0f0d000005568/68b0f0d000005575 |
GO:0017059 |
serine palmitoyltransferase complex |
GO:0004758 |
serine C-palmitoyltransferase activity |
Vitalina Kharchenko |
University of Osnabrueck Molecular Cell Biology Division |
| gomodel:68b0f0d000005840 |
PC transfer by STARD7 mitochondrial intermembrane space (Human) |
production |
gomodel:68b0f0d000005840/69c59f8a00003608 |
GO:0017087 |
mitochondrial processing peptidase complex |
GO:0004222 |
metalloendopeptidase activity |
Vitalina Kharchenko |
University of Osnabrueck Molecular Cell Biology Division |
| gomodel:68b0f0d000005840 |
PC transfer by STARD7 mitochondrial intermembrane space (Human) |
production |
gomodel:68b0f0d000005840/69c59f8a00003573 |
GO:0140596 |
TOM complex |
GO:0008320 |
transmembrane protein transporter activity |
Vitalina Kharchenko |
University of Osnabrueck Molecular Cell Biology Division |
| gomodel:68b0f0d000006133 |
L-leucine catabolic process (Dmel) |
production |
gomodel:68b0f0d000006133/68b0f0d000006348 |
GO:1905202 |
methylcrotonoyl-CoA carboxylase complex |
GO:0004485 |
methylcrotonoyl-CoA carboxylase activity |
Rossana Zaru |
FlyBase |
| gomodel:68b0f0d000006670 |
mitochondrial respirasome assembly (Dmel) |
production |
gomodel:68b0f0d000006670/68b0f0d000006671 |
GO:0045277 |
respiratory chain complex IV |
GO:0004129 |
cytochrome-c oxidase activity |
Helen Attrill |
FlyBase |
| gomodel:68b0f0d000006670 |
mitochondrial respirasome assembly (Dmel) |
production |
gomodel:68b0f0d000006670/68b0f0d000006705 |
GO:0045271 |
respiratory chain complex I |
GO:0008137 |
NADH dehydrogenase (ubiquinone) activity |
Helen Attrill |
FlyBase |
| gomodel:68b0f0d000006670 |
mitochondrial respirasome assembly (Dmel) |
production |
gomodel:68b0f0d000006670/68b0f0d000006723 |
GO:0045275 |
respiratory chain complex III |
GO:0008121 |
quinol-cytochrome-c reductase activity |
Helen Attrill |
FlyBase |
| gomodel:68b0f0d000007160 |
Detoxification of itaconate in macrophages (Human). |
production |
gomodel:68b0f0d000007160/68b0f0d000007253 |
GO:1902494 |
catalytic complex |
GO:0016878 |
acid-thiol ligase activity |
Sylvain Poux |
UniProt |
| gomodel:68b0f0d000007269 |
Detoxification of malyl-CoA by CLYBL (Human). |
production |
gomodel:68b0f0d000007269/68b0f0d000007306 |
GO:1902494 |
catalytic complex |
GO:0016878 |
acid-thiol ligase activity |
Sylvain Poux |
UniProt |
| gomodel:68b0f0d000008746 |
nitrogen utilization (GO:0019740) (ammonia, proline, D-alanine, L-alanine) |
production |
gomodel:68b0f0d000008746/68b0f0d000008781 |
GO:0016591 |
RNA polymerase II, holoenzyme |
GO:0003968 |
RNA-directed RNA polymerase activity |
Val Wood |
PomBase |
| gomodel:68b0f0d000008746 |
nitrogen utilization (GO:0019740) (ammonia, proline, D-alanine, L-alanine) |
production |
gomodel:68b0f0d000008746/68b0f0d000008773 |
GO:0033698 |
Rpd3L complex |
GO:0140937 |
histone H4K12 deacetylase activity, hydrolytic mechanism |
Val Wood |
PomBase |
| gomodel:68d5ebd600000274 |
Neuroprotection involving MT-RNR2 binding to
a receptor complex containing IL27RA, CNTFR and IL6ST (human) |
production |
gomodel:68d5ebd600000274/68d5ebd600000275 |
GO:7770013 |
humanin receptor complex |
GO:0038023 |
signaling receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:68d5ebd600002260 |
CRLF-CLCF1 signaling pathway involving CNTFR-IL6ST-LIFR complex via JAK-STAT (human) |
production |
gomodel:68d5ebd600002260/68d5ebd600002277 |
GO:0097058 |
CRLF-CLCF1 complex |
GO:0005125 |
cytokine activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:68d5ebd600002406 |
CRLF-CLCF1 signaling pathway involving CNTFR-IL6ST-LIFR complex via PTPN11 (human) |
production |
gomodel:68d5ebd600002406/68d5ebd600002407 |
GO:0097058 |
CRLF-CLCF1 complex |
GO:0005125 |
cytokine activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:68d5ebd600002652 |
sCNTFR-CLCF1 signaling pathway involving IL6ST-LIFR complex (human) |
production |
gomodel:68d5ebd600002652/68d5ebd600002653 |
GO:0097059 |
CNTFR-CLCF1 complex |
GO:0005125 |
cytokine activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:68d5ebd600003246 |
CNTF signaling pathway involving soluble CNTFR and the IL6ST-LIFR complex (human) |
production |
gomodel:68d5ebd600003246/68fac5ed00000133 |
GO:0032991 |
protein-containing complex |
GO:0005125 |
cytokine activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:68fac5ed00000572 |
De novo sphingomyelin synthesis via CERS5. (Human) |
production |
gomodel:68fac5ed00000572/68fac5ed00000573 |
GO:0017059 |
serine palmitoyltransferase complex |
GO:0004758 |
serine C-palmitoyltransferase activity |
Cristina Casals |
UniProt |
| gomodel:68fac5ed00003700 |
Green light signaling mediated by OPN1MW3 photoreceptor via G-alpha-t (transducin)_Visual perception (Human) |
production |
gomodel:68fac5ed00003700/69ea894900003537 |
GO:0017071 |
intracellular cyclic nucleotide activated cation channel complex |
GO:0005223 |
intracellularly cGMP-activated cation channel activity |
Lucille Pourcel |
UniProt |
| gomodel:68fac5ed00003872 |
Red light signaling mediated by OPN1LW photoreceptor via G-alpha-t (transducin)_Visual perception (Human) |
production |
gomodel:68fac5ed00003872/69ea894900003340 |
GO:0017071 |
intracellular cyclic nucleotide activated cation channel complex |
GO:0005223 |
intracellularly cGMP-activated cation channel activity |
Lucille Pourcel |
UniProt |
| gomodel:6918f23700000035 |
Dim light signaling mediated by RHO photoreceptor via G-alpha-t (transducin)_Visual perception (Human) |
production |
gomodel:6918f23700000035/6918f23700001883 |
GO:7770030 |
rod photoreceptor phosphodiesterase 6 complex |
GO:0047555 |
3',5'-cyclic-GMP phosphodiesterase activity |
Lucille Pourcel |
UniProt |
| gomodel:6918f23700000035 |
Dim light signaling mediated by RHO photoreceptor via G-alpha-t (transducin)_Visual perception (Human) |
production |
gomodel:6918f23700000035/69ea894900004226 |
GO:0017071 |
intracellular cyclic nucleotide activated cation channel complex |
GO:0005223 |
intracellularly cGMP-activated cation channel activity |
Lucille Pourcel |
UniProt |
| gomodel:6918f23700000529 |
GPR45 acts as a regulator of food intake in the paraventricular nucleus of the hypothalamus by mediating transport of GNAS/G(s) into primary cilia (Human) |
production |
gomodel:6918f23700000529/6918f23700000605 |
GO:0030991 |
intraciliary transport particle A |
GO:0140597 |
protein carrier activity |
Sylvain Poux |
UniProt |
| gomodel:6918f23700000689 |
mitochondrial respiratory chain complex I assembly (Dmel) |
production |
gomodel:6918f23700000689/6918f23700001121 |
GO:0045271 |
respiratory chain complex I |
GO:0008137 |
NADH dehydrogenase (ubiquinone) activity |
Helen Attrill |
FlyBase |
| gomodel:6918f23700002235 |
mitochondrial respiratory chain complex II assembly (Dmel) |
production |
gomodel:6918f23700002235/6918f23700002473 |
GO:0045273 |
respiratory chain complex II (succinate dehydrogenase) |
GO:0008177 |
succinate dehydrogenase (quinone) activity |
Helen Attrill |
FlyBase |
| gomodel:6918f23700002487 |
mitochondrial respiratory chain complex III assembly (Dmel) |
production |
gomodel:6918f23700002487/6918f23700002613 |
GO:0061671 |
Cbp3p-Cbp6 complex |
GO:0097177 |
mitochondrial ribosome binding |
Helen Attrill |
FlyBase |
| gomodel:6918f23700002487 |
mitochondrial respiratory chain complex III assembly (Dmel) |
production |
gomodel:6918f23700002487/6918f23700002621 |
GO:0061671 |
Cbp3p-Cbp6 complex |
GO:0140309 |
unfolded protein holdase activity |
Helen Attrill |
FlyBase |
| gomodel:6918f23700002487 |
mitochondrial respiratory chain complex III assembly (Dmel) |
production |
gomodel:6918f23700002487/6918f23700002829 |
GO:0045275 |
respiratory chain complex III |
GO:0008121 |
quinol-cytochrome-c reductase activity |
Helen Attrill |
FlyBase |
| gomodel:6918f23700002838 |
mitochondrial proton-transporting ATP synthase complex assembly (Dmel) |
production |
gomodel:6918f23700002838/6918f23700002871 |
GO:0045259 |
proton-transporting ATP synthase complex |
GO:0046933 |
proton-transporting ATP synthase activity, rotational mechanism |
Helen Attrill |
FlyBase |
| gomodel:6918f23700003787 |
exocytosis (GO:0006887) for septum assembly (partial)
|
production |
gomodel:6918f23700003787/6918f23700003923 |
GO:1990071 |
TRAPPII protein complex |
GO:0043495 |
protein-membrane adaptor activity |
Val Wood |
PomBase |
| gomodel:6918f23700003787 |
exocytosis (GO:0006887) for septum assembly (partial)
|
production |
gomodel:6918f23700003787/69ea894900001346 |
GO:0031201 |
SNARE complex |
GO:0005484 |
SNAP receptor activity |
Val Wood |
PomBase |
| gomodel:6918f23700003984 |
Golgi to endosome transport (GO:0006895) (partial) |
production |
gomodel:6918f23700003984/6918f23700003985 |
GO:0030121 |
AP-1 adaptor complex |
GO:0035615 |
clathrin-cargo adaptor activity |
Val Wood |
PomBase |
| gomodel:6918f23700003984 |
Golgi to endosome transport (GO:0006895) (partial) |
production |
gomodel:6918f23700003984/6918f23700003994 |
GO:0071439 |
clathrin complex |
GO:0005198 |
structural molecule activity |
Val Wood |
PomBase |
| gomodel:6918f23700004001 |
early endosome to late endosome transport (GO:0045022) late endosome to vacuole transport (GO:0045324) |
production |
gomodel:6918f23700004001/6918f23700004085 |
GO:0031201 |
SNARE complex |
GO:0005484 |
SNAP receptor activity |
Val Wood |
PomBase |
| gomodel:6918f23700004001 |
early endosome to late endosome transport (GO:0045022) late endosome to vacuole transport (GO:0045324) |
production |
gomodel:6918f23700004001/6918f23700004010 |
GO:1902500 |
vacuolar HOPS complex |
GO:0030674 |
protein-macromolecule adaptor activity |
Val Wood |
PomBase |
| gomodel:6918f23700004001 |
early endosome to late endosome transport (GO:0045022) late endosome to vacuole transport (GO:0045324) |
production |
gomodel:6918f23700004001/6918f23700004092 |
GO:0035658 |
Mon1-Ccz1 complex |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
Val Wood |
PomBase |
| gomodel:6918f23700004001 |
early endosome to late endosome transport (GO:0045022) late endosome to vacuole transport (GO:0045324) |
production |
gomodel:6918f23700004001/6918f23700004002 |
GO:0033263 |
CORVET complex |
GO:0030674 |
protein-macromolecule adaptor activity |
Val Wood |
PomBase |
| gomodel:6918f23700004102 |
endosome transport via multivesicular body sorting pathway (GO:0032509) |
production |
gomodel:6918f23700004102/6918f23700004103 |
GO:0000813 |
ESCRT I complex |
GO:0030674 |
protein-macromolecule adaptor activity |
Val Wood |
PomBase |
| gomodel:6918f23700004102 |
endosome transport via multivesicular body sorting pathway (GO:0032509) |
production |
gomodel:6918f23700004102/6918f23700004116 |
GO:0000815 |
ESCRT III complex |
GO:1990606 |
membrane scission GTPase motor activity |
Val Wood |
PomBase |
| gomodel:6918f23700004102 |
endosome transport via multivesicular body sorting pathway (GO:0032509) |
production |
gomodel:6918f23700004102/6918f23700004107 |
GO:0000814 |
ESCRT II complex |
GO:0098772 |
molecular function regulator activity |
Val Wood |
PomBase |
| gomodel:6918f23700004102 |
endosome transport via multivesicular body sorting pathway (GO:0032509) |
production |
gomodel:6918f23700004102/6918f23700004133 |
GO:0033565 |
ESCRT-0 complex |
GO:0030674 |
protein-macromolecule adaptor activity |
Val Wood |
PomBase |
| gomodel:6918f23700004722 |
clathrin-dependent endocytosis (GO:0072583) |
production |
gomodel:6918f23700004722/6918f23700004857 |
GO:0005885 |
Arp2/3 protein complex |
GO:0003779 |
actin binding |
Val Wood |
PomBase |
| gomodel:6918f23700004722 |
clathrin-dependent endocytosis (GO:0072583) |
production |
gomodel:6918f23700004722/693b3c0900002859 |
GO:0008290 |
F-actin capping protein complex |
GO:0051015 |
actin filament binding |
Val Wood |
PomBase |
| gomodel:6918f23700004722 |
clathrin-dependent endocytosis (GO:0072583) |
production |
gomodel:6918f23700004722/6918f23700004833 |
GO:0071439 |
clathrin complex |
GO:0005198 |
structural molecule activity |
Val Wood |
PomBase |
| gomodel:6918f23700004722 |
clathrin-dependent endocytosis (GO:0072583) |
production |
gomodel:6918f23700004722/69c59f8a00002570 |
GO:0031941 |
filamentous actin |
GO:0005200 |
structural constituent of cytoskeleton |
Val Wood |
PomBase |
| gomodel:6918f23700004722 |
clathrin-dependent endocytosis (GO:0072583) |
production |
gomodel:6918f23700004722/6918f23700004820 |
GO:0030122 |
AP-2 adaptor complex |
GO:0035615 |
clathrin-cargo adaptor activity |
Val Wood |
PomBase |
| gomodel:6918f23700004722 |
clathrin-dependent endocytosis (GO:0072583) |
production |
gomodel:6918f23700004722/693b3c0900003149 |
GO:1990528 |
Rvs161p-Rvs167p complex |
GO:0043495 |
protein-membrane adaptor activity |
Val Wood |
PomBase |
| gomodel:693b3c0900000051 |
TULP3 and IFT-A complex mediate transport of GPR161 to primary cilium (Human). |
production |
gomodel:693b3c0900000051/693b3c0900000113 |
GO:0030991 |
intraciliary transport particle A |
GO:0140597 |
protein carrier activity |
Sylvain Poux |
UniProt |
| gomodel:693b3c0900000536 |
pheromone response MAPK cascade (GO:0071507) |
production |
gomodel:693b3c0900000536/693b3c0900001226 |
GO:0005965 |
protein farnesyltransferase complex |
GO:0004660 |
protein farnesyltransferase activity |
Val Wood |
PomBase |
| gomodel:693b3c0900000716 |
GPR161 is exported from primary cilium in response to smoothened signaling via a beta-arrestin, BBSome and IFT-B complex-dependent mechanism (Human). |
production |
gomodel:693b3c0900000716/693b3c0900000856 |
GO:0030992 |
intraciliary transport particle B |
GO:0140597 |
protein carrier activity |
Sylvain Poux |
UniProt |
| gomodel:693b3c0900000716 |
GPR161 is exported from primary cilium in response to smoothened signaling via a beta-arrestin, BBSome and IFT-B complex-dependent mechanism (Human). |
production |
gomodel:693b3c0900000716/693b3c0900000830 |
GO:0034464 |
BBSome |
GO:0140597 |
protein carrier activity |
Sylvain Poux |
UniProt |
| gomodel:693b3c0900002174 |
retrograde transport endosome to Golgi (GO:0042147) (partial) |
production |
gomodel:693b3c0900002174/693b3c0900002220 |
GO:0000938 |
GARP complex |
GO:7770062 |
vesicle membrane tethering activity |
Val Wood |
PomBase |
| gomodel:693b3c0900002174 |
retrograde transport endosome to Golgi (GO:0042147) (partial) |
production |
gomodel:693b3c0900002174/693b3c0900002185 |
GO:0030905 |
retromer, tubulation complex |
GO:0180020 |
membrane bending activity |
Val Wood |
PomBase |
| gomodel:693b3c0900002174 |
retrograde transport endosome to Golgi (GO:0042147) (partial) |
production |
gomodel:693b3c0900002174/693b3c0900002239 |
GO:0031201 |
SNARE complex |
GO:0005484 |
SNAP receptor activity |
Val Wood |
PomBase |
| gomodel:693b3c0900002174 |
retrograde transport endosome to Golgi (GO:0042147) (partial) |
production |
gomodel:693b3c0900002174/696022cd00000218 |
GO:0034066 |
Ric1-Rgp1 guanyl-nucleotide exchange factor complex |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
Val Wood |
PomBase |
| gomodel:693b3c0900002174 |
retrograde transport endosome to Golgi (GO:0042147) (partial) |
production |
gomodel:693b3c0900002174/693b3c0900002175 |
GO:0030906 |
retromer, cargo-selective complex |
GO:0140312 |
cargo adaptor activity |
Val Wood |
PomBase |
| gomodel:693b3c0900003452 |
ascospore-type prospore membrane formation (GO:0032120) ascospore wall biogenesis (GO:0070591) (partial) |
production |
gomodel:693b3c0900003452/693b3c0900003572 |
GO:0000145 |
exocyst |
GO:0005546 |
phosphatidylinositol-4,5-bisphosphate binding |
Val Wood |
PomBase |
| gomodel:693b3c0900003452 |
ascospore-type prospore membrane formation (GO:0032120) ascospore wall biogenesis (GO:0070591) (partial) |
production |
gomodel:693b3c0900003452/69c59f8a00000917 |
GO:0031201 |
SNARE complex |
GO:0140522 |
fusogenic activity |
Val Wood |
PomBase |
| gomodel:693b3c0900004140 |
mating projection formation (GO:0031382), mating projection tip cell wall disassembly (GO:1904541), cytogamy (GO:0000755)
|
production |
gomodel:693b3c0900004140/6994852c00002751 |
GO:0031941 |
filamentous actin |
GO:0005200 |
structural constituent of cytoskeleton |
Val Wood |
PomBase |
| gomodel:693b3c0900004140 |
mating projection formation (GO:0031382), mating projection tip cell wall disassembly (GO:1904541), cytogamy (GO:0000755)
|
production |
gomodel:693b3c0900004140/69c59f8a00000443 |
GO:0000145 |
exocyst |
GO:7770062 |
vesicle membrane tethering activity |
Val Wood |
PomBase |
| gomodel:693b3c0900004140 |
mating projection formation (GO:0031382), mating projection tip cell wall disassembly (GO:1904541), cytogamy (GO:0000755)
|
production |
gomodel:693b3c0900004140/69c59f8a00000447 |
GO:0031201 |
SNARE complex |
GO:0140522 |
fusogenic activity |
Val Wood |
PomBase |
| gomodel:693b3c0900004859 |
endoplasmic reticulum to Golgi vesicle-mediated transport (GO:0006888) (partial) |
production |
gomodel:693b3c0900004859/69d8496c00002764 |
GO:1990070 |
TRAPPI protein complex |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
Val Wood |
PomBase |
| gomodel:693b3c0900004859 |
endoplasmic reticulum to Golgi vesicle-mediated transport (GO:0006888) (partial) |
production |
gomodel:693b3c0900004859/69c59f8a00000967 |
GO:0031201 |
SNARE complex |
GO:0140522 |
fusogenic activity |
Val Wood |
PomBase |
| gomodel:693b3c0900004859 |
endoplasmic reticulum to Golgi vesicle-mediated transport (GO:0006888) (partial) |
production |
gomodel:693b3c0900004859/693b3c0900004928 |
GO:7770070 |
p24 cargo receptor complex |
GO:0097020 |
COPII receptor activity |
Val Wood |
PomBase |
| gomodel:693b3c0900005911 |
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (GO:0006890) |
production |
gomodel:693b3c0900005911/69d8496c00005191 |
GO:0031201 |
SNARE complex |
GO:0140522 |
fusogenic activity |
Val Wood |
PomBase |
| gomodel:693b3c0900005911 |
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (GO:0006890) |
production |
gomodel:693b3c0900005911/69d8496c00003728 |
GO:0061852 |
retrograde cargo receptor complex, Golgi to ER |
GO:0038024 |
cargo receptor activity |
Val Wood |
PomBase |
| gomodel:693b3c0900005911 |
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (GO:0006890) |
production |
gomodel:693b3c0900005911/693b3c0900005914 |
GO:0030126 |
COPI vesicle coat |
GO:0140312 |
cargo adaptor activity |
Val Wood |
PomBase |
| gomodel:693b3c0900005911 |
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (GO:0006890) |
production |
gomodel:693b3c0900005911/693b3c0900006082 |
GO:0070939 |
Dsl1/NZR complex |
GO:7770062 |
vesicle membrane tethering activity |
Val Wood |
PomBase |
| gomodel:696022cd00000908 |
SCUBE2, CDON, BOC and GAS1 promote SHH transport to PTCH1 receptor (Human). |
production |
gomodel:696022cd00000908/696022cd00000972 |
GO:0032991 |
protein-containing complex |
GO:0140597 |
protein carrier activity |
Sylvain Poux |
UniProt |
| gomodel:696022cd00002138 |
OSM signaling pathway involving IL6ST-LIFR receptor complex (human) |
production |
gomodel:696022cd00002138/69729a3800000169 |
GO:0140370 |
type II oncostatin-M receptor complex |
GO:0004924 |
oncostatin-M receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:696022cd00002481 |
OSM signaling pathway involving IL6ST-OSMR receptor complex (human) |
production |
gomodel:696022cd00002481/696022cd00002572 |
GO:0005900 |
type I oncostatin-M receptor complex |
GO:0004924 |
oncostatin-M receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:69729a3800000296 |
CTF1 signaling pathway involving IL6ST-LIFR receptor complex (human) |
production |
gomodel:69729a3800000296/69729a3800000346 |
GO:0140370 |
type II oncostatin-M receptor complex |
GO:0004924 |
oncostatin-M receptor activity |
Guilaine Argoud-Puy |
UniProt |
| gomodel:69729a3800000481 |
MAST3 kinase regulates ARPP19 phosphatase activity and is down-regulated by PKA |
production |
gomodel:69729a3800000481/69729a3800001020 |
GO:0008287 |
protein serine/threonine phosphatase complex |
GO:0004721 |
phosphoprotein phosphatase activity |
Livia Famiglietti |
UniProt |
| gomodel:69729a3800001528 |
CD36 transport to the plasma membrane for muscle regeneration (Human) |
production |
gomodel:69729a3800001528/69729a3800003578 |
GO:0031201 |
SNARE complex |
GO:0140522 |
fusogenic activity |
Lionel Breuza |
UniProt |
| gomodel:69729a3800002581 |
beta barrel protein insertion into mitochondrial outer membrane (D.mel) |
production |
gomodel:69729a3800002581/69729a3800002653 |
GO:0042719 |
mitochondrial intermembrane space chaperone complex |
GO:0140309 |
unfolded protein holdase activity |
Helen Attrill |
FlyBase |
| gomodel:69729a3800002651 |
beta barrel protein insertion into mitochondrial outer membrane (GO:7770063) |
production |
gomodel:69729a3800002651/69729a3800002738 |
GO:0042719 |
mitochondrial intermembrane space chaperone complex |
GO:0140309 |
unfolded protein holdase activity |
Val Wood |
PomBase |
| gomodel:69729a3800004162 |
Vesicle fusion in cytotoxic T cell degranulation (Human) |
production |
gomodel:69729a3800004162/69729a3800004163 |
GO:0031201 |
SNARE complex |
GO:0140522 |
fusogenic activity |
Lionel Breuza |
UniProt |
| gomodel:69729a3800008725 |
SLC45A1 mediates hexose efflux from lysosomes and is required for V-ATPase activity (Human). |
production |
gomodel:69729a3800008725/69729a3800008741 |
GO:0046611 |
lysosomal proton-transporting V-type ATPase complex |
GO:0046961 |
proton-transporting ATPase activity, rotational mechanism |
Sylvain Poux |
UniProt |
| gomodel:698e557b00000129 |
The V-ATPase complex promotes the guanyl-nucleotide exchange factor activity of the Ragulator complex during mTORC1 signaling (Human). |
production |
gomodel:698e557b00000129/698e557b00000367 |
GO:0046611 |
lysosomal proton-transporting V-type ATPase complex |
GO:0160124 |
guanyl nucleotide exchange factor activator activity |
Sylvain Poux |
UniProt |
| gomodel:698e557b00000129 |
The V-ATPase complex promotes the guanyl-nucleotide exchange factor activity of the Ragulator complex during mTORC1 signaling (Human). |
production |
gomodel:698e557b00000129/698e557b00000130 |
GO:0071986 |
Ragulator complex |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
Sylvain Poux |
UniProt |
| gomodel:698e557b00000391 |
PSENEN binds metformin in response to calorie restriction and inhibits the V-ATPase complex, inhibiting mTORC1 signaling (Human). |
production |
gomodel:698e557b00000391/698e557b00000392 |
GO:0071986 |
Ragulator complex |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
Sylvain Poux |
UniProt |
| gomodel:698e557b00000391 |
PSENEN binds metformin in response to calorie restriction and inhibits the V-ATPase complex, inhibiting mTORC1 signaling (Human). |
production |
gomodel:698e557b00000391/698e557b00000504 |
GO:0046611 |
lysosomal proton-transporting V-type ATPase complex |
GO:0160124 |
guanyl nucleotide exchange factor activator activity |
Sylvain Poux |
UniProt |
| gomodel:698e557b00001137 |
Inhibition of mTORC1 signaling by the AXIN1-STK11 axis in response to glucose starvation (Human). |
production |
gomodel:698e557b00001137/698e557b00001250 |
GO:0046611 |
lysosomal proton-transporting V-type ATPase complex |
GO:0160124 |
guanyl nucleotide exchange factor activator activity |
Sylvain Poux |
UniProt |
| gomodel:6994852c00000143 |
TOM-TIM22-mediated mitochondrial inner membrane protein insertion (GO:7770061) |
production |
gomodel:6994852c00000143/6994852c00000637 |
GO:0042719 |
mitochondrial intermembrane space chaperone complex |
GO:0140309 |
unfolded protein holdase activity |
Val Wood |
PomBase |
| gomodel:6994852c00000143 |
TOM-TIM22-mediated mitochondrial inner membrane protein insertion (GO:7770061) |
production |
gomodel:6994852c00000143/6994852c00000631 |
GO:0042719 |
mitochondrial intermembrane space chaperone complex |
GO:0140309 |
unfolded protein holdase activity |
Val Wood |
PomBase |
| gomodel:6994852c00000205 |
Mitochondrial TOM-TIM22 inner membrane carrier pathway (D.mel) |
production |
gomodel:6994852c00000205/69b3372b00003605 |
GO:0042719 |
mitochondrial intermembrane space chaperone complex |
GO:0140309 |
unfolded protein holdase activity |
Helen Attrill |
FlyBase |
| gomodel:69a0c46f00000571 |
Branched-chain amino acid catabolic process 1(Mouse) |
production |
gomodel:69a0c46f00000571/69a0c46f00000695 |
GO:0032991 |
protein-containing complex |
GO:0004485 |
methylcrotonoyl-CoA carboxylase activity |
David Hill |
MGI |
| gomodel:69a0c46f00000571 |
Branched-chain amino acid catabolic process 1(Mouse) |
production |
gomodel:69a0c46f00000571/69a0c46f00000688 |
GO:0032991 |
protein-containing complex |
GO:0003863 |
branched-chain 2-oxo acid dehydrogenase activity |
David Hill |
MGI |
| gomodel:69a0c46f00001390 |
Branched-chain amino acid catabolic process 2(Mouse) |
production |
gomodel:69a0c46f00001390/69a0c46f00001459 |
GO:0032991 |
protein-containing complex |
GO:0003863 |
branched-chain 2-oxo acid dehydrogenase activity |
David Hill |
MGI |
| gomodel:69a0c46f00001542 |
Branched-chain amino acid catabolic process 3(Mouse) |
production |
gomodel:69a0c46f00001542/69a0c46f00001611 |
GO:0032991 |
protein-containing complex |
GO:0003863 |
branched-chain 2-oxo acid dehydrogenase activity |
David Hill |
MGI |
| gomodel:69a0c46f00003187 |
alpha helical protein insertion into mitochondrial outer membrane (GO:7770059) |
production |
gomodel:69a0c46f00003187/69a0c46f00003201 |
GO:0140595 |
MIM complex |
GO:0032977 |
membrane insertase activity |
Val Wood |
PomBase |
| gomodel:69a0c46f00003691 |
pyrimidine nucleobase metabolic process (GO:0006206) |
production |
gomodel:69a0c46f00003691/69a0c46f00003915 |
GO:0045275 |
respiratory chain complex III |
GO:0008121 |
quinol-cytochrome-c reductase activity |
Pascal Carme |
PomBase |
| gomodel:69b3372b00000379 |
cellular response to copper ion starvation (GO:0035874) |
production |
gomodel:69b3372b00000379/69b3372b00000392 |
GO:1903113 |
copper ion transmembrane transporter complex |
GO:0005375 |
copper ion transmembrane transporter activity |
Val Wood |
PomBase |
| gomodel:69b3372b00003343 |
FSH delivery to granulosa cells promotes follicle development (Human) |
production |
gomodel:69b3372b00003343/69b3372b00003379 |
GO:0016914 |
follicle-stimulating hormone complex |
GO:0016913 |
follicle-stimulating hormone activity |
Patrick Masson |
UniProt |
| gomodel:69c59f8a00002219 |
post-chaperonin tubulin folding pathway (GO:0007023) |
production |
gomodel:69c59f8a00002219/69c59f8a00002246 |
GO:0016272 |
prefoldin complex |
GO:0140309 |
unfolded protein holdase activity |
Val Wood |
PomBase |
| gomodel:69c59f8a00002219 |
post-chaperonin tubulin folding pathway (GO:0007023) |
production |
gomodel:69c59f8a00002219/69c59f8a00002293 |
GO:0045298 |
tubulin complex |
GO:0005200 |
structural constituent of cytoskeleton |
Val Wood |
PomBase |
| gomodel:69c59f8a00002219 |
post-chaperonin tubulin folding pathway (GO:0007023) |
production |
gomodel:69c59f8a00002219/69c59f8a00002230 |
GO:0005832 |
chaperonin-containing T-complex |
GO:0140662 |
ATP-dependent protein folding chaperone |
Val Wood |
PomBase |
| gomodel:69d8496c00002213 |
ARFGAP2 has GTPase activating activity for ARF1 during COPI vesicle formation (Human). |
production |
gomodel:69d8496c00002213/69d8496c00002232 |
GO:0030126 |
COPI vesicle coat |
GO:0140597 |
protein carrier activity |
Sylvain Poux |
UniProt |
| gomodel:69d8496c00004645 |
mitochondrial ribosome assembly (GO:0061668) |
production |
gomodel:69d8496c00004645/69d8496c00004729 |
GO:0005762 |
mitochondrial large ribosomal subunit |
GO:0030674 |
protein-macromolecule adaptor activity |
Val Wood |
PomBase |
| gomodel:69ea894900000564 |
In liver, 12(S)-HEPE activates OR5V1-mediated signaling via G-alpha-s ("stimulatory", activating adenylate cyclase) and regulating glucose homeostasis (Human). |
production |
gomodel:69ea894900000564/69ea894900000616 |
GO:0005952 |
cAMP-dependent protein kinase complex |
GO:0004691 |
cAMP-dependent protein kinase activity |
Sylvain Poux |
UniProt |
| gomodel:69ea894900003563 |
Green light signaling mediated by OPN1MW photoreceptor via G-alpha-t (transducin)_Visual perception (Human) |
production |
gomodel:69ea894900003563/69ea894900003612 |
GO:0017071 |
intracellular cyclic nucleotide activated cation channel complex |
GO:0005223 |
intracellularly cGMP-activated cation channel activity |
Lucille Pourcel |
UniProt |
| gomodel:69ea894900003638 |
Green light signaling mediated by OPN1MW2 photoreceptor via G-alpha-t (transducin)_Visual perception (Human) |
production |
gomodel:69ea894900003638/69ea894900003687 |
GO:0017071 |
intracellular cyclic nucleotide activated cation channel complex |
GO:0005223 |
intracellularly cGMP-activated cation channel activity |
Lucille Pourcel |
UniProt |
| gomodel:69ea894900003713 |
Blue light signaling mediated by OPN1SW photoreceptor via G-alpha-t (transducin)_Visual perception (Human) |
production |
gomodel:69ea894900003713/69ea894900003762 |
GO:0017071 |
intracellular cyclic nucleotide activated cation channel complex |
GO:0005223 |
intracellularly cGMP-activated cation channel activity |
Lucille Pourcel |
UniProt |
| gomodel:69ea894900004256 |
CNG channel transport by ankyrin-G/ANK3_Visual perception (Human) |
production |
gomodel:69ea894900004256/69ea894900004257 |
GO:0017071 |
intracellular cyclic nucleotide activated cation channel complex |
GO:0005223 |
intracellularly cGMP-activated cation channel activity |
Lucille Pourcel |
UniProt |
| gomodel:6a0784b700000336 |
cGMP recovery by CGAP1 and RetGC1 through negative feedback loop in cones_Visual perception (Human) |
production |
gomodel:6a0784b700000336/6a0784b700000476 |
GO:0017071 |
intracellular cyclic nucleotide activated cation channel complex |
GO:0005223 |
intracellularly cGMP-activated cation channel activity |
Lucille Pourcel |
UniProt |
| gomodel:6a0784b700000502 |
cGMP recovery by CGAP2 and RetGC2 through negative feedback loop in rods_Visual perception (Human) |
production |
gomodel:6a0784b700000502/6a0784b700000539 |
GO:0017071 |
intracellular cyclic nucleotide activated cation channel complex |
GO:0005223 |
intracellularly cGMP-activated cation channel activity |
Lucille Pourcel |
UniProt |
| gomodel:6a0784b700005841 |
cGMP recovery by CGAP3 and RetGC1 through negative feedback loop in cones_Visual perception (Human) |
production |
gomodel:6a0784b700005841/6a0784b700005878 |
GO:0017071 |
intracellular cyclic nucleotide activated cation channel complex |
GO:0005223 |
intracellularly cGMP-activated cation channel activity |
Lucille Pourcel |
UniProt |
| gomodel:6a18a9ba00000016 |
Golgi to vacuole transport (GO:0006896) (ALP pathway) (partial) |
production |
gomodel:6a18a9ba00000016/6a18a9ba00000017 |
GO:0030123 |
AP-3 adaptor complex |
GO:0140312 |
cargo adaptor activity |
Val Wood |
PomBase |
| gomodel:6a18a9ba00000016 |
Golgi to vacuole transport (GO:0006896) (ALP pathway) (partial) |
production |
gomodel:6a18a9ba00000016/6a18a9ba00000025 |
GO:0031201 |
SNARE complex |
GO:0005484 |
SNAP receptor activity |
Val Wood |
PomBase |
| gomodel:6a2b236300001691 |
CENP-A containing chromatin assembly (GO:0034080) |
production |
gomodel:6a2b236300001691/6a2b236300001699 |
GO:0098654 |
CENP-A recruiting complex |
GO:0140463 |
chromatin-protein adaptor activity |
Val Wood |
PomBase |
| gomodel:6a2b236300001691 |
CENP-A containing chromatin assembly (GO:0034080) |
production |
gomodel:6a2b236300001691/6a2b236300001742 |
GO:0031511 |
Mis6-Sim4 complex |
GO:0003674 |
molecular_function |
Val Wood |
PomBase |
| gomodel:6a46ef0600000404 |
RNA polymerase II preinitiation complex assembly (GO:0051123), transcription initiation at RNA polymerase II promoter (GO:0006367) (TATA-less promoter) |
production |
gomodel:6a46ef0600000404/6a46ef0600000452 |
GO:0005665 |
RNA polymerase II, core complex |
GO:0140378 |
protein complex scaffold activity |
Val Wood |
PomBase |
| gomodel:6a46ef0600000404 |
RNA polymerase II preinitiation complex assembly (GO:0051123), transcription initiation at RNA polymerase II promoter (GO:0006367) (TATA-less promoter) |
production |
gomodel:6a46ef0600000404/6a46ef0600000405 |
GO:0005672 |
transcription factor TFIIA complex |
GO:0016251 |
RNA polymerase II general transcription initiation factor activity |
Val Wood |
PomBase |
| gomodel:6a46ef0600000404 |
RNA polymerase II preinitiation complex assembly (GO:0051123), transcription initiation at RNA polymerase II promoter (GO:0006367) (TATA-less promoter) |
production |
gomodel:6a46ef0600000404/6a46ef0600000439 |
GO:0005674 |
transcription factor TFIIF complex |
GO:0016251 |
RNA polymerase II general transcription initiation factor activity |
Val Wood |
PomBase |
| gomodel:6a46ef0600000404 |
RNA polymerase II preinitiation complex assembly (GO:0051123), transcription initiation at RNA polymerase II promoter (GO:0006367) (TATA-less promoter) |
production |
gomodel:6a46ef0600000404/6a46ef0600000706 |
GO:0005665 |
RNA polymerase II, core complex |
GO:0003968 |
RNA-directed RNA polymerase activity |
Val Wood |
PomBase |
| gomodel:6a46ef0600000404 |
RNA polymerase II preinitiation complex assembly (GO:0051123), transcription initiation at RNA polymerase II promoter (GO:0006367) (TATA-less promoter) |
production |
gomodel:6a46ef0600000404/6a46ef0600000485 |
GO:0000439 |
transcription factor TFIIH core complex |
GO:0043139 |
5'-3' DNA helicase activity |
Val Wood |
PomBase |
| gomodel:6a46ef0600000404 |
RNA polymerase II preinitiation complex assembly (GO:0051123), transcription initiation at RNA polymerase II promoter (GO:0006367) (TATA-less promoter) |
production |
gomodel:6a46ef0600000404/6a46ef0600000672 |
GO:0016592 |
mediator complex |
GO:0060090 |
molecular adaptor activity |
Val Wood |
PomBase |
| gomodel:6a46ef0600000404 |
RNA polymerase II preinitiation complex assembly (GO:0051123), transcription initiation at RNA polymerase II promoter (GO:0006367) (TATA-less promoter) |
production |
gomodel:6a46ef0600000404/6a46ef0600000479 |
GO:0005673 |
transcription factor TFIIE complex |
GO:0016251 |
RNA polymerase II general transcription initiation factor activity |
Val Wood |
PomBase |
| gomodel:6a4c244800004776 |
ETF-Etf-QO mediated regeneration of mitochondrial FAD (Dmel) |
production |
gomodel:6a4c244800004776/6a4c244800005000 |
GO:0017133 |
mitochondrial electron transfer flavoprotein complex |
GO:0009055 |
electron transfer activity |
Rossana Zaru |
FlyBase |
| gomodel:MGI_MGI_1340031 |
Nfkbil1 (MGI:MGI:1340031) |
production |
gomodel:MGI_MGI_1340031/65039e8700001611 |
GO:0071159 |
NF-kappaB complex |
GO:0003700 |
DNA-binding transcription factor activity |
David Hill |
MGI |
| gomodel:R-HSA-1482798 |
Acyl chain remodeling of CL - imported from: Reactome |
production |
gomodel:R-HSA-1482775 |
GO:0032991 |
protein-containing complex |
GO:0016747 |
acyltransferase activity, transferring groups other than amino-acyl groups |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-1483213 |
Synthesis of PE - imported from: Reactome |
production |
gomodel:R-HSA-1483222_enabled_by_R-HSA-1500617_R-HSA-1483222_controller |
GO:0032991 |
protein-containing complex |
GO:0004305 |
ethanolamine kinase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-1483248 |
Synthesis of PIPs at the ER membrane - imported from: Reactome |
production |
gomodel:R-HSA-6809777 |
GO:0032991 |
protein-containing complex |
GO:0004438 |
phosphatidylinositol-3-phosphate phosphatase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-1483248 |
Synthesis of PIPs at the ER membrane - imported from: Reactome |
production |
gomodel:R-HSA-6809778 |
GO:0032991 |
protein-containing complex |
GO:0052629 |
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-156581 |
Methylation - imported from: Reactome |
production |
gomodel:R-HSA-6800149 |
GO:0032991 |
protein-containing complex |
GO:0008168 |
methyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-156581 |
Methylation - imported from: Reactome |
production |
gomodel:R-HSA-5603114 |
GO:0032991 |
protein-containing complex |
GO:0004478 |
methionine adenosyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-163210 |
Formation of ATP by chemiosmotic coupling - imported from: Reactome |
production |
gomodel:R-HSA-164832 |
GO:0032991 |
protein-containing complex |
GO:0046933 |
proton-transporting ATP synthase activity, rotational mechanism |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-163210 |
Formation of ATP by chemiosmotic coupling - imported from: Reactome |
production |
gomodel:R-HSA-164834 |
GO:0032991 |
protein-containing complex |
GO:0015078 |
proton transmembrane transporter activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-170822 |
Regulation of Glucokinase by Glucokinase Regulatory Protein - imported from: Reactome |
production |
gomodel:R-HSA-170796_enabled_by_REACTO_R-HSA-157689_combo7867c9ad_R-HSA-170796_controller |
GO:0032991 |
protein-containing complex |
GO:0017056 |
structural constituent of nuclear pore |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-170822 |
Regulation of Glucokinase by Glucokinase Regulatory Protein - imported from: Reactome |
production |
gomodel:R-HSA-170796_enabled_by_REACTO_R-HSA-157689_combofeed844c_R-HSA-170796_controller |
GO:0032991 |
protein-containing complex |
GO:0017056 |
structural constituent of nuclear pore |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-170822 |
Regulation of Glucokinase by Glucokinase Regulatory Protein - imported from: Reactome |
production |
gomodel:R-HSA-170796_enabled_by_REACTO_R-HSA-157689_comboa465780b_R-HSA-170796_controller |
GO:0032991 |
protein-containing complex |
GO:0017056 |
structural constituent of nuclear pore |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-170822 |
Regulation of Glucokinase by Glucokinase Regulatory Protein - imported from: Reactome |
production |
gomodel:R-HSA-170796_enabled_by_REACTO_R-HSA-157689_combo9589c84a_R-HSA-170796_controller |
GO:0032991 |
protein-containing complex |
GO:0017056 |
structural constituent of nuclear pore |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-170822 |
Regulation of Glucokinase by Glucokinase Regulatory Protein - imported from: Reactome |
production |
gomodel:R-HSA-170796_enabled_by_REACTO_R-HSA-157689_combod221c96b_R-HSA-170796_controller |
GO:0032991 |
protein-containing complex |
GO:0017056 |
structural constituent of nuclear pore |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-170822 |
Regulation of Glucokinase by Glucokinase Regulatory Protein - imported from: Reactome |
production |
gomodel:R-HSA-170796_enabled_by_REACTO_R-HSA-157689_combof040dab_R-HSA-170796_controller |
GO:0032991 |
protein-containing complex |
GO:0017056 |
structural constituent of nuclear pore |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-170822 |
Regulation of Glucokinase by Glucokinase Regulatory Protein - imported from: Reactome |
production |
gomodel:R-HSA-170796_enabled_by_REACTO_R-HSA-157689_combo1ddfbd6c_R-HSA-170796_controller |
GO:0032991 |
protein-containing complex |
GO:0017056 |
structural constituent of nuclear pore |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-170822 |
Regulation of Glucokinase by Glucokinase Regulatory Protein - imported from: Reactome |
production |
gomodel:R-HSA-170796_enabled_by_REACTO_R-HSA-157689_combo4b9c0ecc_R-HSA-170796_controller |
GO:0032991 |
protein-containing complex |
GO:0017056 |
structural constituent of nuclear pore |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-174403 |
Glutathione synthesis and recycling - imported from: Reactome |
production |
gomodel:R-HSA-174367 |
GO:0032991 |
protein-containing complex |
GO:0004357 |
glutamate-cysteine ligase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022857 |
Keratan sulfate degradation - imported from: Reactome |
production |
gomodel:R-HSA-1638053 |
GO:0032991 |
protein-containing complex |
GO:0004563 |
beta-N-acetylhexosaminidase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022870 |
CS-GAG biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-1971487_enabled_by_REACTO_R-HSA-9941504_Q86X52_Q8IZ52_R-HSA-1971487_controller |
GO:0032991 |
protein-containing complex |
GO:0047238 |
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022870 |
CS-GAG biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-1971491_enabled_by_REACTO_R-HSA-9941504_Q70JA7_Q9P2E5_R-HSA-1971491_controller |
GO:0032991 |
protein-containing complex |
GO:0050510 |
N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022870 |
CS-GAG biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-1971491_enabled_by_REACTO_R-HSA-9941504_Q86X52_Q8IZ52_R-HSA-1971491_controller |
GO:0032991 |
protein-containing complex |
GO:0050510 |
N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022870 |
CS-GAG biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-1971487_enabled_by_REACTO_R-HSA-9941504_Q70JA7_Q9P2E5_R-HSA-1971487_controller |
GO:0032991 |
protein-containing complex |
GO:0047238 |
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022870 |
CS-GAG biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-1971491_enabled_by_REACTO_R-HSA-9941504_Q70JA7_Q8IZ52_R-HSA-1971491_controller |
GO:0032991 |
protein-containing complex |
GO:0050510 |
N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022870 |
CS-GAG biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-1971487_enabled_by_REACTO_R-HSA-9941504_Q70JA7_Q8IZ52_R-HSA-1971487_controller |
GO:0032991 |
protein-containing complex |
GO:0047238 |
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022870 |
CS-GAG biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-1971491_enabled_by_REACTO_R-HSA-9941504_Q86X52_Q9P2E5_R-HSA-1971491_controller |
GO:0032991 |
protein-containing complex |
GO:0050510 |
N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022870 |
CS-GAG biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-1971487_enabled_by_REACTO_R-HSA-9941504_Q86X52_Q9P2E5_R-HSA-1971487_controller |
GO:0032991 |
protein-containing complex |
GO:0047238 |
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022928 |
HS-GAG biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-2076392 |
GO:0032991 |
protein-containing complex |
GO:0050509 |
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022928 |
HS-GAG biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-2022856 |
GO:0032991 |
protein-containing complex |
GO:0050509 |
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2022928 |
HS-GAG biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-2022851 |
GO:0032991 |
protein-containing complex |
GO:0050508 |
glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2024101 |
CS/DS degradation - imported from: Reactome |
production |
gomodel:R-HSA-2105001 |
GO:0032991 |
protein-containing complex |
GO:0004563 |
beta-N-acetylhexosaminidase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2160916 |
Hyaluronan degradation - imported from: Reactome |
production |
gomodel:R-HSA-2162225 |
GO:0032991 |
protein-containing complex |
GO:0004563 |
beta-N-acetylhexosaminidase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2564830 |
Cytosolic iron-sulfur cluster assembly - imported from: Reactome |
production |
gomodel:R-HSA-2564828 |
GO:0032991 |
protein-containing complex |
GO:0036455 |
iron-sulfur transferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-2564830 |
Cytosolic iron-sulfur cluster assembly - imported from: Reactome |
production |
gomodel:R-HSA-2564826 |
GO:0032991 |
protein-containing complex |
GO:0060090 |
molecular adaptor activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-350562 |
Regulation of ornithine decarboxylase (ODC) - imported from: Reactome |
production |
gomodel:R-HSA-353125 |
GO:0032991 |
protein-containing complex |
GO:0004175 |
endopeptidase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-611105 |
Respiratory electron transport - imported from: Reactome |
production |
gomodel:R-HSA-164651 |
GO:0032991 |
protein-containing complex |
GO:0008121 |
quinol-cytochrome-c reductase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-611105 |
Respiratory electron transport - imported from: Reactome |
production |
gomodel:R-HSA-169260 |
GO:0032991 |
protein-containing complex |
GO:0009055 |
electron transfer activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-611105 |
Respiratory electron transport - imported from: Reactome |
production |
gomodel:R-HSA-163213 |
GO:0032991 |
protein-containing complex |
GO:0008177 |
succinate dehydrogenase (quinone) activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-611105 |
Respiratory electron transport - imported from: Reactome |
production |
gomodel:R-HSA-163214 |
GO:0032991 |
protein-containing complex |
GO:0004129 |
cytochrome-c oxidase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-71032 |
Propionyl-CoA catabolism - imported from: Reactome |
production |
gomodel:R-HSA-71031 |
GO:0032991 |
protein-containing complex |
GO:0004658 |
propionyl-CoA carboxylase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-71403 |
Citric acid cycle (TCA cycle) - imported from: Reactome |
production |
gomodel:R-HSA-71775 |
GO:0032991 |
protein-containing complex |
GO:0004776 |
succinate-CoA ligase (GDP-forming) activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-71403 |
Citric acid cycle (TCA cycle) - imported from: Reactome |
production |
gomodel:R-HSA-70994 |
GO:0032991 |
protein-containing complex |
GO:0008177 |
succinate dehydrogenase (quinone) activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-71403 |
Citric acid cycle (TCA cycle) - imported from: Reactome |
production |
gomodel:R-HSA-70997 |
GO:0032991 |
protein-containing complex |
GO:0004775 |
succinate-CoA ligase (ADP-forming) activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-77285 |
Beta oxidation of myristoyl-CoA to lauroyl-CoA - imported from: Reactome |
production |
gomodel:R-HSA-77283 |
GO:0032991 |
protein-containing complex |
GO:0003857 |
(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-77285 |
Beta oxidation of myristoyl-CoA to lauroyl-CoA - imported from: Reactome |
production |
gomodel:R-HSA-77271 |
GO:0032991 |
protein-containing complex |
GO:0003988 |
acetyl-CoA C-acyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-77285 |
Beta oxidation of myristoyl-CoA to lauroyl-CoA - imported from: Reactome |
production |
gomodel:R-HSA-77277 |
GO:0032991 |
protein-containing complex |
GO:0004300 |
enoyl-CoA hydratase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-77305 |
Beta oxidation of palmitoyl-CoA to myristoyl-CoA - imported from: Reactome |
production |
gomodel:R-HSA-77301 |
GO:0032991 |
protein-containing complex |
GO:0004300 |
enoyl-CoA hydratase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-77305 |
Beta oxidation of palmitoyl-CoA to myristoyl-CoA - imported from: Reactome |
production |
gomodel:R-HSA-77304 |
GO:0032991 |
protein-containing complex |
GO:0003988 |
acetyl-CoA C-acyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-77305 |
Beta oxidation of palmitoyl-CoA to myristoyl-CoA - imported from: Reactome |
production |
gomodel:R-HSA-77303 |
GO:0032991 |
protein-containing complex |
GO:0003857 |
(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-77310 |
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA - imported from: Reactome |
production |
gomodel:R-HSA-77309 |
GO:0032991 |
protein-containing complex |
GO:0003988 |
acetyl-CoA C-acyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-77346 |
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA - imported from: Reactome |
production |
gomodel:R-HSA-77340 |
GO:0032991 |
protein-containing complex |
GO:0003988 |
acetyl-CoA C-acyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-77348 |
Beta oxidation of octanoyl-CoA to hexanoyl-CoA - imported from: Reactome |
production |
gomodel:R-HSA-77329 |
GO:0032991 |
protein-containing complex |
GO:0003988 |
acetyl-CoA C-acyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-77350 |
Beta oxidation of hexanoyl-CoA to butanoyl-CoA - imported from: Reactome |
production |
gomodel:R-HSA-77321 |
GO:0032991 |
protein-containing complex |
GO:0003988 |
acetyl-CoA C-acyltransferase activity |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-947581 |
Molybdenum cofactor biosynthesis - imported from: Reactome |
production |
gomodel:R-HSA-947535 |
GO:0032991 |
protein-containing complex |
GO:1904047 |
S-adenosyl-L-methionine binding |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-9859138 |
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV - imported from: Reactome |
production |
gomodel:R-HSA-9859148 |
GO:0032991 |
protein-containing complex |
GO:0016624 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-9865881 |
Complex III assembly - imported from: Reactome |
production |
gomodel:R-HSA-9865893 |
GO:0032991 |
protein-containing complex |
GO:0044183 |
protein folding chaperone |
Curators at Reactome |
Reactome |
| gomodel:R-HSA-9865881 |
Complex III assembly - imported from: Reactome |
production |
gomodel:R-HSA-9866132 |
GO:0032991 |
protein-containing complex |
GO:0005515 |
protein binding |
Curators at Reactome |
Reactome |
| gomodel:YeastPathways_ARGSYNBSUB-PWY |
L-arginine biosynthesis II (acetyl cycle) - imported from: Saccharomyces Genome Database |
production |
gomodel:CARBPSYN-RXN |
SGD:S000217863 |
|
GO:0004088 |
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity |
Curators at SGD |
SGD |
| gomodel:YeastPathways_BRANCHED-CHAIN-AA-SYN-PWY-1 |
superpathway of branched chain amino acid biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:ACETOLACTSYN-RXN |
SGD:S000218137 |
|
GO:0003984 |
acetolactate synthase activity |
Curators at SGD |
SGD |
| gomodel:YeastPathways_BRANCHED-CHAIN-AA-SYN-PWY-1 |
superpathway of branched chain amino acid biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:ACETOOHBUTSYN-RXN |
SGD:S000218137 |
|
GO:0003984 |
acetolactate synthase activity |
Curators at SGD |
SGD |
| gomodel:YeastPathways_CITRUL-BIO2-PWY |
citrulline biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:CARBPSYN-RXN |
SGD:S000217863 |
|
GO:0004088 |
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity |
Stacia Engel |
SGD |
| gomodel:YeastPathways_COMPLETE-ARO-PWY-1 |
superpathway of aromatic amino acid biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:ANTHRANSYN-RXN |
SGD:S000218001 |
|
GO:0004049 |
anthranilate synthase activity |
Curators at SGD |
SGD |
| gomodel:YeastPathways_DENOVOPURINE2-PWY |
superpathway of purine nucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database |
production |
gomodel:GDPREDUCT-RXN |
SGD:S000217933 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_DENOVOPURINE2-PWY |
superpathway of purine nucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database |
production |
gomodel:YeastPathways_DENOVOPURINE2-PWY/6a4c244800007444 |
SGD:S000217934 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_DENOVOPURINE2-PWY |
superpathway of purine nucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database |
production |
gomodel:ADPREDUCT-RXN |
SGD:S000217933 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_DENOVOPURINE2-PWY |
superpathway of purine nucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database |
production |
gomodel:YeastPathways_DENOVOPURINE2-PWY/6a4c244800007414 |
SGD:S000217934 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_DENOVOPURINE3-PWY |
de novo biosynthesis of purine nucleotides - imported from: Saccharomyces Genome Database |
production |
gomodel:ADPREDUCT-RXN |
SGD:S000217933 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_DENOVOPURINE3-PWY |
de novo biosynthesis of purine nucleotides - imported from: Saccharomyces Genome Database |
production |
gomodel:YeastPathways_DENOVOPURINE3-PWY/6a4c244800005867 |
SGD:S000217934 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_DENOVOPURINE3-PWY |
de novo biosynthesis of purine nucleotides - imported from: Saccharomyces Genome Database |
production |
gomodel:YeastPathways_DENOVOPURINE3-PWY/6a4c244800005893 |
SGD:S000217934 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_DENOVOPURINE3-PWY |
de novo biosynthesis of purine nucleotides - imported from: Saccharomyces Genome Database |
production |
gomodel:GDPREDUCT-RXN |
SGD:S000217933 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_GLUCFERMEN-PWY |
superpathway of glucose fermentation - imported from: Saccharomyces Genome Database |
production |
gomodel:6PFRUCTPHOS-RXN |
SGD:S000218025 |
|
GO:0003872 |
6-phosphofructokinase activity |
Curators at SGD |
SGD |
| gomodel:YeastPathways_GLUCOSE-MANNOSYL-CHITO-DOLICHOL |
lipid-linked oligosaccharide biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:2.4.1.141-RXN |
SGD:S000217964 |
|
GO:0004577 |
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity |
Stacia Engel |
SGD |
| gomodel:YeastPathways_GLYCOLYSIS |
glycolysis I (from glucose 6-phosphate) - imported from: Saccharomyces Genome Database |
production |
gomodel:6PFRUCTPHOS-RXN |
SGD:S000218025 |
|
GO:0003872 |
6-phosphofructokinase activity |
Stacia Engel |
SGD |
| gomodel:YeastPathways_ILEUSYN-PWY-1 |
L-isoleucine biosynthesis I (from threonine) - imported from: Saccharomyces Genome Database |
production |
gomodel:ACETOOHBUTSYN-RXN |
SGD:S000218137 |
|
GO:0003984 |
acetolactate synthase activity |
Stacia Engel |
SGD |
| gomodel:YeastPathways_PRPP-PWY-1 |
superpathway of histidine, purine, and pyrimidine biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:GDPREDUCT-RXN |
SGD:S000217933 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_PRPP-PWY-1 |
superpathway of histidine, purine, and pyrimidine biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:ADPREDUCT-RXN |
SGD:S000217933 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_PRPP-PWY-1 |
superpathway of histidine, purine, and pyrimidine biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:GDPREDUCT-RXN |
SGD:S000217934 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_PRPP-PWY-1 |
superpathway of histidine, purine, and pyrimidine biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:ADPREDUCT-RXN |
SGD:S000217934 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_PWY-6126-1 |
superpathway of adenosine nucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database |
production |
gomodel:ADPREDUCT-RXN |
SGD:S000217933 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_PWY-6126-1 |
superpathway of adenosine nucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database |
production |
gomodel:YeastPathways_PWY-6126-1/6a4c244800001617 |
SGD:S000217934 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_PWY-6482-1 |
diphthamide biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:RXN-11371 |
SGD:S000345846 |
|
GO:0090560 |
2-(3-amino-3-carboxypropyl)histidine synthase activity |
Curators at SGD |
SGD |
| gomodel:YeastPathways_PWY-7220-1 |
adenosine deoxyribonucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database |
production |
gomodel:ADPREDUCT-RXN |
SGD:S000217933 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_PWY-7220-1 |
adenosine deoxyribonucleotides <i>de novo</i> biosynthesis II - imported from: Saccharomyces Genome Database |
production |
gomodel:YeastPathways_PWY-7220-1/6a2b236300005372 |
SGD:S000217934 |
|
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
Stacia Engel |
SGD |
| gomodel:YeastPathways_PWY-781 |
sulfate assimilation pathway - imported from: Saccharomyces Genome Database |
production |
gomodel:SULFITE-REDUCT-RXN |
SGD:S000217821 |
|
GO:0004783 |
sulfite reductase (NADPH) activity |
Curators at SGD |
SGD |
| gomodel:YeastPathways_PWY-821-1 |
superpathway of sulfur amino acid biosynthesis (<i>Saccharomyces cerevisiae</i>) - imported from: Saccharomyces Genome Database |
production |
gomodel:SULFITE-REDUCT-RXN |
SGD:S000217821 |
|
GO:0004783 |
sulfite reductase (NADPH) activity |
Stacia Engel |
SGD |
| gomodel:YeastPathways_PWY3O-697 |
folate interconversions - imported from: Saccharomyces Genome Database |
production |
gomodel:GCVMULTI-RXN |
SGD:S000218158 |
|
GO:0004375 |
glycine dehydrogenase (decarboxylating) activity |
Edith Wong |
SGD |
| gomodel:YeastPathways_SO4ASSIM-PWY |
assimilatory sulfate reduction I - imported from: Saccharomyces Genome Database |
production |
gomodel:SULFITE-REDUCT-RXN |
SGD:S000217821 |
|
GO:0004783 |
sulfite reductase (NADPH) activity |
Curators at SGD |
SGD |
| gomodel:YeastPathways_SPHINGOLIPID-SYN-PWY-1 |
sphingolipid biosynthesis (yeast) - imported from: Saccharomyces Genome Database |
production |
gomodel:RXN3O-328 |
SGD:S000218096 |
|
GO:0050291 |
sphingosine N-acyltransferase activity |
Stacia Engel |
SGD |
| gomodel:YeastPathways_SPHINGOLIPID-SYN-PWY-1 |
sphingolipid biosynthesis (yeast) - imported from: Saccharomyces Genome Database |
production |
gomodel:RXN3O-663 |
SGD:S000218211 |
|
GO:0000030 |
mannosyltransferase activity |
Stacia Engel |
SGD |
| gomodel:YeastPathways_TRPSYN-PWY-1 |
L-tryptophan biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:ANTHRANSYN-RXN |
SGD:S000218001 |
|
GO:0004049 |
anthranilate synthase activity |
Stacia Engel |
SGD |
| gomodel:YeastPathways_VALSYN-PWY |
L-valine biosynthesis - imported from: Saccharomyces Genome Database |
production |
gomodel:ACETOLACTSYN-RXN |
SGD:S000218137 |
|
GO:0003984 |
acetolactate synthase activity |
Stacia Engel |
SGD |