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Siroheme, a modified cyclic tetrapyrrole, similar in structure to heme, chlorophyll and cobalamin, is used as a prosthetic group by sulfite and nitrite reductases |CITS: [4583265]|. Similar to many cyclic tetrapyrroles, siroheme coordinates with a metal in its central cavity. While siroheme and heme coordinate an iron atom, chlorophyll and cobalamin coordinate maganesium and cobalt, respectively. Assimilatory sulfite reductases are found in bacteria, plants and fungi, but not in animals, while dissimilatory sulfite reductases are found in diverse sulfate-reducing eubacteria and some species of thermophilic archaebacteria |CITS: [8994874]|. Assimilatory nitrite reductases are also found in bacteria, plants, and fungi |CITS: [8994874]|, but not in the yeast Saccharomyces cerevisiae. Thus, in \u003ci\u003eS. cerevisiae\u003c/i\u003e siroheme is used exclusively in sulfite reductase. 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