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assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0002-2286-1587"},{"key":"contributor","value":"https://orcid.org/0000-0002-4973-5732"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"source","value":"PMID:27624722"},{"key":"date","value":"2024-03-06"}]}],"facts":[{"subject":"gomodel:SYNGO_502538efb80f-516f-4e78-8655-53669b777e2d","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:SYNGO_5025bc35e76e-bdcc-4c89-84b9-9a9c0d10b45b","annotations":[{"key":"evidence","value":"gomodel:SYNGO_5025897c65f0-d772-41ee-962d-a201f4de4d6c","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_50258ff2805f-9a21-4b5b-a36b-745206bfbf39","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0002-2286-1587"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"contributor","value":"https://orcid.org/0000-0002-4973-5732"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"}]},{"subject":"gomodel:SYNGO_502538efb80f-516f-4e78-8655-53669b777e2d","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:SYNGO_50254b6bb578-6584-466b-9135-09cb6e5a7447","annotations":[{"key":"evidence","value":"gomodel:SYNGO_502572d88b88-5541-4287-af01-dec31837b391","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_5025f678052e-2922-4fdd-9c99-43be4885c874","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0002-2286-1587"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"contributor","value":"https://orcid.org/0000-0002-4973-5732"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"}]}],"annotations":[{"key":"state","value":"production"},{"key":"contributor","value":"https://orcid.org/0000-0002-2286-1587"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"contributor","value":"https://orcid.org/0000-0002-4973-5732"},{"key":"date","value":"2023-02-18"},{"key":"title","value":"SYNGO_BP_5025"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"comment","value":"Rationale: Figures 2-4: 3D structures of spines of 8-week-old WT, Reelin-OE (overexpressing) and Dab1-cKO GFP/DAB-labeled granule cells were reconstructed with FIB/SEM microscopy. Reelin and Dab1 both altered newborn granule cells dendritic spine morphology.\n\nAuthors conclude from these analyses that \"This proves that spines are more irregularly shaped in 8-9 weeks Reelin-OE and Dab1-cKO neurons, and suggests that spine structural maturation is affected by the Reelin signaling. Synapse sphericity was smaller in Reelin-OE mice at 8-9 weeks, indicating greater complexity (Fig.4d).\". Experimental description: M\u0026M: \"Conditional knockout Dab1 mice (Dab1-cKO) (Pramatarova et al. 2008) and Reelin-overexpressing (Reelin-OE, gamma strain) (Pujadas et al. 2010) mice were maintained on a C57BL/6 J background. \""},{"key":"https://w3id.org/biolink/vocab/in_taxon","value":"http://purl.obolibrary.org/obo/NCBITaxon_10090"}]}