{"id":"gomodel:SYNGO_3530","individuals":[{"id":"gomodel:SYNGO_353047c4ee81-d9d1-4b20-b638-c6e7169678f8","type":[{"type":"class","id":"GO:0003674","label":"molecular_function"}],"root-type":[{"type":"class","id":"GO:0003674","label":"molecular_function"},{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0000-0001-9377-7414"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0002-9880-1214"},{"key":"contributor","value":"https://orcid.org/0000-0002-0269-0311"},{"key":"contributor","value":"https://orcid.org/0000-0002-9681-3318"}]},{"id":"gomodel:SYNGO_3530493b7e4f-7691-4b99-9a86-889cb3ca61f0","type":[{"type":"class","id":"ECO:0000303","label":"author statement without traceable support used in manual 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presynapse"}],"root-type":[{"type":"class","id":"GO:0008150","label":"biological_process"}],"annotations":[{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"date","value":"2024-03-06"},{"key":"contributor","value":"https://orcid.org/0000-0002-9681-3318"},{"key":"contributor","value":"https://orcid.org/0000-0001-9377-7414"},{"key":"contributor","value":"https://orcid.org/0000-0002-0269-0311"},{"key":"contributor","value":"https://orcid.org/0000-0002-9880-1214"}]}],"facts":[{"subject":"gomodel:SYNGO_353047c4ee81-d9d1-4b20-b638-c6e7169678f8","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:SYNGO_3530a284df7e-7a07-455e-8508-20db6428c189","annotations":[{"key":"evidence","value":"gomodel:SYNGO_3530b13a5356-456c-4b0c-bd33-a06c9b7e8d98","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-9377-7414"},{"key":"contributor","value":"https://orcid.org/0000-0002-0269-0311"},{"key":"contributor","value":"https://orcid.org/0000-0002-9681-3318"},{"key":"contributor","value":"https://orcid.org/0000-0002-9880-1214"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"}]},{"subject":"gomodel:SYNGO_353047c4ee81-d9d1-4b20-b638-c6e7169678f8","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:SYNGO_3530b150aa7e-a53d-48fa-8860-5eca9d71f3fa","annotations":[{"key":"evidence","value":"gomodel:SYNGO_3530493b7e4f-7691-4b99-9a86-889cb3ca61f0","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-9377-7414"},{"key":"contributor","value":"https://orcid.org/0000-0002-0269-0311"},{"key":"contributor","value":"https://orcid.org/0000-0002-9681-3318"},{"key":"contributor","value":"https://orcid.org/0000-0002-9880-1214"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"}]}],"annotations":[{"key":"state","value":"production"},{"key":"contributor","value":"https://orcid.org/0000-0001-9377-7414"},{"key":"contributor","value":"https://orcid.org/0000-0002-0269-0311"},{"key":"contributor","value":"https://orcid.org/0000-0002-9681-3318"},{"key":"contributor","value":"https://orcid.org/0000-0002-9880-1214"},{"key":"date","value":"2018-05-28"},{"key":"title","value":"SYNGO_BP_3530"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"comment","value":"Rationale: 18/5/2018 Pim\nrule: NAS_CPLX_1\nrationale: Ribosomes are present in the axonal compartment (Fig.1, RL22 used as marker protein using the RiboTag mouse line; electron and fluorescence microscopy) and protein translation is shown to occur in this compartment (PMID:27321671). RLA0 is a generally accepted constituent of the ribosome. No functions of RLA0 are known independent from the ribosomal complex. Inference to term \"translation (GO:0006412)\" occurs_in \"presynapse (GO:0098793)\" is trivial.\nC_ref CC: SynGO ID #1681 (\"presynaptic ribosome\")\nP_inf CC: SynGO ID #617\nP_inf CC additional:\n- Bayes et al.(2012), PMID:23071613, TableS1, prep:psd\n- Collins et al.(2006), PMID:16635246, consensus, prep:psd\n- Distler et al.(2014), PMID:25211037, Table S1, prep:synapse\nComplex membership: RLA0 protein is a fixed member of the 60S ribosomal subunit complex.\n- Shown in crystal structure (PMID:28138070, see Fig.1, name: uL10)\n- GO annotations to \"structural constituent of ribosome (GO:0003735)\" (ISO and IEA). Experimental description: \"In brief, in the original method, forebrains of 30 days old untreated rats were homogenized in homogenization buffer ..\". P. 988"},{"key":"https://w3id.org/biolink/vocab/in_taxon","value":"http://purl.obolibrary.org/obo/NCBITaxon_10116"}]}