{"id":"gomodel:SYNGO_189","individuals":[{"id":"gomodel:SYNGO_189132909ec-6736-45bb-8d4c-01f9a8ef7c44","type":[{"type":"class","id":"ECO:0007695","label":"cell-based assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2024-03-06"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"source","value":"PMID:8126562"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"}]},{"id":"gomodel:SYNGO_1892e6a468a-94ab-4545-834f-40d74e931660","type":[{"type":"class","id":"ECO:0006063","label":"over expression analysis evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"source","value":"PMID:8126562"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"}]},{"id":"gomodel:SYNGO_1893cdf29a3-f5a1-4e8c-9529-1fe80d3e76a2","type":[{"type":"class","id":"RGD:2949","label":"Kcna1 Rnor"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"}],"annotations":[{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"}]},{"id":"gomodel:SYNGO_1898608f0ab-eded-4d4c-9d5a-926d7bbd98fa","type":[{"type":"class","id":"ECO:0000303","label":"author statement without traceable support used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:8126562"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"date","value":"2024-03-06"}]},{"id":"gomodel:SYNGO_189c70d1103-b30b-443d-a57f-8cce8384a982","type":[{"type":"class","id":"GO:1905030","label":"voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential"}],"root-type":[{"type":"class","id":"GO:0003674","label":"molecular_function"},{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"date","value":"2024-03-06"}]},{"id":"gomodel:SYNGO_189dd1598fc-3257-4e0a-8916-c64366289204","type":[{"type":"class","id":"ECO:0006013","label":"patch-clamp recording evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:8126562"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"}]}],"facts":[{"subject":"gomodel:SYNGO_189c70d1103-b30b-443d-a57f-8cce8384a982","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:SYNGO_1893cdf29a3-f5a1-4e8c-9529-1fe80d3e76a2","annotations":[{"key":"evidence","value":"gomodel:SYNGO_189132909ec-6736-45bb-8d4c-01f9a8ef7c44","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_1892e6a468a-94ab-4545-834f-40d74e931660","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_1898608f0ab-eded-4d4c-9d5a-926d7bbd98fa","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_189dd1598fc-3257-4e0a-8916-c64366289204","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"}]}],"annotations":[{"key":"state","value":"production"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"date","value":"2018-06-29"},{"key":"title","value":"SYNGO_MF_189"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"comment","value":"Rationale: Expression of channels in Mouse L-cells (fybroblasts).\n\nrule: NAS_MFCC-BP\nrationale:\nProtein has voltage-gated ion channel activity and is localized in teh presynaptic membrane (show with high-resolution technique). The inference to term \u0027voltage-gated ion channel activity involved in regulation of presynaptic membrane potential (GO:0099508)\u0027 is trivial and non-controversial.\nPinf_CC:\n[P10499] SyNGO ID 180 (PMID:14614103, confocal). Experimental description: p.1667: he primary channel chosen for this work was originally cloned from rat brain as RCKl (Baumann et al., 1988) and RBKl (Christie et al., 1989) and from rat aorta as RKl (Roberds and Tamkun, 1991). Under the universal nomenclature (Chandy,1991) this channel is defined as Kvl.1 since it is homologous to the Drosophila Shaker family of K+ channels"},{"key":"https://w3id.org/biolink/vocab/in_taxon","value":"http://purl.obolibrary.org/obo/NCBITaxon_10116"}]}