{"id":"gomodel:SYNGO_1339","individuals":[{"id":"gomodel:SYNGO_1339688742ce-1988-414a-9ef2-0767ce26aeca","type":[{"type":"class","id":"MGI:MGI:1860139","label":"Gabbr1 Mmus"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"date","value":"2024-03-06"}]},{"id":"gomodel:SYNGO_1339a469e384-101a-4676-a884-9960e2ca498c","type":[{"type":"class","id":"ECO:0007695","label":"cell-based assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"source","value":"PMID:10075644"},{"key":"date","value":"2024-03-06"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"}]},{"id":"gomodel:SYNGO_1339bcedd855-9b0a-466a-8d0a-4d3e6309a786","type":[{"type":"class","id":"ECO:0006013","label":"patch-clamp recording evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:10075644"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"}]},{"id":"gomodel:SYNGO_1339c77b5e3a-8800-4d2d-b872-63b3b1fb16c9","type":[{"type":"class","id":"ECO:0006063","label":"over expression analysis evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"date","value":"2024-03-06"},{"key":"source","value":"PMID:10075644"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"}]},{"id":"gomodel:SYNGO_1339d54ef730-bcc7-4610-8a35-cb4599839850","type":[{"type":"class","id":"ECO:0000303","label":"author statement without traceable support used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:10075644"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"}]},{"id":"gomodel:SYNGO_1339e095e03f-ff83-4a37-8990-1e7f60ca5a55","type":[{"type":"class","id":"GO:0099528","label":"G protein-coupled neurotransmitter receptor activity"}],"root-type":[{"type":"class","id":"GO:0003674","label":"molecular_function"},{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"date","value":"2026-01-08"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"comment","value":"Automated change 2026-01-08: GO:0150047 replaced by GO:0099528"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"}]}],"facts":[{"subject":"gomodel:SYNGO_1339e095e03f-ff83-4a37-8990-1e7f60ca5a55","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:SYNGO_1339688742ce-1988-414a-9ef2-0767ce26aeca","annotations":[{"key":"evidence","value":"gomodel:SYNGO_1339a469e384-101a-4676-a884-9960e2ca498c","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_1339bcedd855-9b0a-466a-8d0a-4d3e6309a786","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_1339c77b5e3a-8800-4d2d-b872-63b3b1fb16c9","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_1339d54ef730-bcc7-4610-8a35-cb4599839850","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"}]}],"annotations":[{"key":"state","value":"production"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"date","value":"2026-01-08"},{"key":"title","value":"SYNGO_MF_1339"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"comment","value":"Automated change 2026-01-08: GO:0150047 replaced by GO:0099528"},{"key":"comment","value":"Rationale: Patch clamp recordings of potassium currents evoked by activation of G-protein couples GABAB R\u0027s containing subunit 1 expressed in Xenopus Oocytes.\n\nrule: NAS_MFCC-BP\nrationale:\nProtein has G-protein neurotransmitter receptor activity and is localized in the presynaptic membrane (shown with high-resolution technique). The inference to term \u0027G-protein coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential (GO:0150047)\u0027 is trivial and non-controversial.\nPinf_CC:\n[Q9Z0U4] SyNGO ID 1251 (PMID:17924569, EM). Experimental description: Expression Constructs for gb1a and gb2 Receptors-The murine gb1a (mgb1a) cDNA was constructed from two expressed sequence tags (IMAGE Consortium clone identification numbers 472408 and 319196), combined by standard PCR methods, and subcloned into the pCINeo (Stratagene) and pcDNA3.1 (Invitrogen) vectors."},{"key":"https://w3id.org/biolink/vocab/in_taxon","value":"http://purl.obolibrary.org/obo/NCBITaxon_10090"}]}