{"id":"gomodel:SYNGO_1336","individuals":[{"id":"gomodel:SYNGO_1336127d0993-adc8-4506-9287-1fa49f34a8ec","type":[{"type":"class","id":"ECO:0006063","label":"over expression analysis evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"source","value":"PMID:26592470"},{"key":"date","value":"2024-03-06"}]},{"id":"gomodel:SYNGO_133629c99a20-d870-48e3-9d4d-a163933b1e34","type":[{"type":"class","id":"RGD:2650","label":"Gabrb2 Rnor"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"}],"annotations":[{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"date","value":"2024-03-06"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"}]},{"id":"gomodel:SYNGO_1336a2d76005-bcaf-43c3-aa8a-90453129f4f9","type":[{"type":"class","id":"GO:0099507","label":"ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential"}],"root-type":[{"type":"class","id":"GO:0003674","label":"molecular_function"},{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"date","value":"2024-03-06"}]},{"id":"gomodel:SYNGO_1336bcc34264-6db5-447f-a0a0-2764579d4ce2","type":[{"type":"class","id":"ECO:0006013","label":"patch-clamp recording evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"source","value":"PMID:26592470"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"date","value":"2024-03-06"}]},{"id":"gomodel:SYNGO_1336c2ef4aa3-e585-49dc-b28c-9ea34714ea8a","type":[{"type":"class","id":"ECO:0000303","label":"author statement without traceable support used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:26592470"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"date","value":"2024-03-06"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"}]},{"id":"gomodel:SYNGO_1336d1143902-0ee8-4aec-a3da-8b46e9c892cb","type":[{"type":"class","id":"ECO:0007695","label":"cell-based assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2024-03-06"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"source","value":"PMID:26592470"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"}]}],"facts":[{"subject":"gomodel:SYNGO_1336a2d76005-bcaf-43c3-aa8a-90453129f4f9","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:SYNGO_133629c99a20-d870-48e3-9d4d-a163933b1e34","annotations":[{"key":"evidence","value":"gomodel:SYNGO_1336127d0993-adc8-4506-9287-1fa49f34a8ec","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_1336bcc34264-6db5-447f-a0a0-2764579d4ce2","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_1336c2ef4aa3-e585-49dc-b28c-9ea34714ea8a","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_1336d1143902-0ee8-4aec-a3da-8b46e9c892cb","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"}]}],"annotations":[{"key":"state","value":"production"},{"key":"contributor","value":"https://orcid.org/0000-0001-9425-2935"},{"key":"contributor","value":"https://orcid.org/0000-0002-2514-0216"},{"key":"date","value":"2018-06-29"},{"key":"title","value":"SYNGO_MF_1336"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"comment","value":"Rationale: WC patch-clamp current measurements of beta 2 containing GABAR\u0027s expressed in HEK cells.\n\nrule: NAS_MFCC-BP\nrationale:\nProtein has ligand-gated ion channel receptor activity and is localized in the presynaptic membrane (shown with high-resolution technique). The inference to term ligand-gated ion channel activity involved in regulation of presynaptic membrane potential (GO:0099507) is trivial and non-controversial.\nPinf_CC:\n[P63138] SyNGO ID 1270 (PMID:14686901, EM)\n[P63138] SyNGO ID 1276 (PMID:15174078, EM). Experimental description: cDNA for GABAR subunits mouse alpha"},{"key":"https://w3id.org/biolink/vocab/in_taxon","value":"http://purl.obolibrary.org/obo/NCBITaxon_10116"}]}