{"id":"gomodel:SYNGO_1255","individuals":[{"id":"gomodel:SYNGO_1255539266d1-9619-44ef-bf2e-bf07cbeb6ee3","type":[{"type":"class","id":"GO:0003674","label":"molecular_function"}],"root-type":[{"type":"class","id":"GO:0003674","label":"molecular_function"},{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-7806-5662"},{"key":"date","value":"2024-03-06"}]},{"id":"gomodel:SYNGO_1255659f0513-54a1-4110-a5f0-d5b722480d9c","type":[{"type":"class","id":"GO:0048488","label":"synaptic vesicle endocytosis"}],"root-type":[{"type":"class","id":"GO:0008150","label":"biological_process"}],"annotations":[{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-7806-5662"},{"key":"date","value":"2024-03-06"}]},{"id":"gomodel:SYNGO_12556fce1e9f-0fa1-4383-9b5e-b2d12e67c0f1","type":[{"type":"class","id":"UniProtKB:F6M3L0"}],"root-type":[],"annotations":[{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"date","value":"2024-03-06"},{"key":"contributor","value":"https://orcid.org/0000-0001-7806-5662"}]},{"id":"gomodel:SYNGO_125588964b83-a12b-403c-8506-1878369c0c81","type":[{"type":"class","id":"ECO:0006054","label":"pharmacological assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0000-0001-7806-5662"},{"key":"source","value":"PMID:21957258"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"date","value":"2024-03-06"}]},{"id":"gomodel:SYNGO_125589b7b65c-d012-4679-8bc5-f2ae5b0323d6","type":[{"type":"class","id":"ECO:0006003","label":"electron microscopy evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-7806-5662"},{"key":"source","value":"PMID:21957258"}]},{"id":"gomodel:SYNGO_1255a2b9c1e5-208d-4fef-9ea6-2ed076f9cf16","type":[{"type":"class","id":"ECO:0006003","label":"electron microscopy evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:21957258"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-7806-5662"}]},{"id":"gomodel:SYNGO_1255cea6105c-210c-4ed2-b101-2c20bf1a186a","type":[{"type":"class","id":"ECO:0006054","label":"pharmacological assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"contributor","value":"https://orcid.org/0000-0001-7806-5662"},{"key":"source","value":"PMID:21957258"}]}],"facts":[{"subject":"gomodel:SYNGO_1255539266d1-9619-44ef-bf2e-bf07cbeb6ee3","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:SYNGO_1255659f0513-54a1-4110-a5f0-d5b722480d9c","annotations":[{"key":"evidence","value":"gomodel:SYNGO_125588964b83-a12b-403c-8506-1878369c0c81","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_125589b7b65c-d012-4679-8bc5-f2ae5b0323d6","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7806-5662"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"}]},{"subject":"gomodel:SYNGO_1255539266d1-9619-44ef-bf2e-bf07cbeb6ee3","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:SYNGO_12556fce1e9f-0fa1-4383-9b5e-b2d12e67c0f1","annotations":[{"key":"evidence","value":"gomodel:SYNGO_1255a2b9c1e5-208d-4fef-9ea6-2ed076f9cf16","value-type":"IRI"},{"key":"evidence","value":"gomodel:SYNGO_1255cea6105c-210c-4ed2-b101-2c20bf1a186a","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7806-5662"},{"key":"date","value":"2024-03-06"},{"key":"providedBy","value":"https://syngo.vu.nl"}]}],"annotations":[{"key":"state","value":"production"},{"key":"contributor","value":"https://orcid.org/0000-0001-7806-5662"},{"key":"date","value":"2017-10-10"},{"key":"title","value":"SYNGO_BP_1255"},{"key":"providedBy","value":"https://syngo.vu.nl"},{"key":"comment","value":"Rationale: The authors use the lamprey reticulospinal synapse. They inject an antibody (function blocking) into the pre synapse. They stimulate the neurons for 30 min at 5 Hz to activate SV exo/endocytosis. In the antibody injected neurons there is a large accumulation of clathrin-coated tubules.\n\n15/8/2017 Pim\n- The lamprey accession was found via Blast of the human EHD1 protein. Experimental description: From the abstract, \"We have investigated the role of an EHD1/3 ortholog (l-EHD) in the lamprey giant reticulospinal synapse\""}]}