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PAR1 antagonism also attenuated late-stage coagulation (Fig. 1c)  indicating that continuing activation of coagulation and inflammation are coupled by a common upstream mechanism.|contributor-id\u003dhttps://orcid.org/0000-0003-3394-9805"},{"key":"comment","value":"MGI:MGI:101802  RO:0002264 GO:0030194 MGI:MGI:3784647|PMID:18305483 ECO:0000315 MGI:MGI:3038377  2008-07-28 MGI  creation-date\u003d2008-07-28|modification-date\u003d2008-07-28|comment\u003dLike PAR1 deficiency  PAR1 antagonism also attenuated late-stage coagulation (Fig. 1c)  indicating that continuing activation of coagulation and inflammation are coupledby a common upstream mechanism.|contributor-id\u003dhttps://orcid.org/0000-0003-3394-9805"}]},{"subject":"gomodel:MGI_MGI_101802/3ffb1b6e-b838-4983-899e-1fee512d0613","property":"RO:0002418","property-label":"RO:0002418","object":"gomodel:MGI_MGI_101802/216c2f27-6b61-4e00-a8c1-9357208b4780","annotations":[{"key":"evidence","value":"gomodel:MGI_MGI_101802/42b6ef51-5b90-4071-8d35-795645df719a","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7476-6306"},{"key":"date","value":"2010-05-03"},{"key":"dc:created","value":"2010-05-03"},{"key":"dc:dateAccepted","value":"2022-03-28"},{"key":"providedBy","value":"http://informatics.jax.org"},{"key":"comment","value":"MGI:MGI:101802  RO:0002264 GO:0070493 MGI:MGI:3810206|PMID:18398001 ECO:0000316 MGI:MGI:88380  2010-05-03 MGI  creation-date\u003d2010-05-03|modification-date\u003d2010-05-03|comment\u003danatomy vibrissa follicle ; MA:0002910|comment\u003dcell type primary cell line cell ; CL:0000001|contributor-id\u003dhttps://orcid.org/0000-0001-7476-6306"}]},{"subject":"gomodel:MGI_MGI_101802/540542a1-8ca1-4be3-87cd-ddd97816f233","property":"RO:0002418","property-label":"RO:0002418","object":"gomodel:MGI_MGI_101802/d9d30ad2-d691-47d4-a3a6-0450396485df","annotations":[{"key":"evidence","value":"gomodel:MGI_MGI_101802/5e35ac48-720e-4107-80fa-68f1f47b848e","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7476-6306"},{"key":"date","value":"2010-05-03"},{"key":"dc:created","value":"2010-05-03"},{"key":"dc:dateAccepted","value":"2022-03-28"},{"key":"providedBy","value":"http://informatics.jax.org"},{"key":"comment","value":"MGI:MGI:101802  RO:0002264 GO:0014068 MGI:MGI:3810206|PMID:18398001 ECO:0000316 MGI:MGI:88380  2010-05-03 MGI  creation-date\u003d2010-05-03|modification-date\u003d2010-05-03|comment\u003danatomy vibrissa follicle ; MA:0002910|comment\u003dcell type primary cell line cell ; CL:0000001|contributor-id\u003dhttps://orcid.org/0000-0001-7476-6306"}]},{"subject":"gomodel:MGI_MGI_101802/ee1c7951-a253-4285-8a77-3bbeedc1a328","property":"RO:0002418","property-label":"RO:0002418","object":"gomodel:MGI_MGI_101802/0050b1be-38f8-4137-97d4-36ae0c777f01","annotations":[{"key":"evidence","value":"gomodel:MGI_MGI_101802/c2b2f88c-a561-42d5-a172-0714cc179435","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0003-2689-5511"},{"key":"contributor","value":"https://orcid.org/0000-0003-3394-9805"},{"key":"date","value":"2010-01-12"},{"key":"dc:created","value":"2008-07-28"},{"key":"dc:dateAccepted","value":"2022-03-28"},{"key":"providedBy","value":"http://informatics.jax.org"},{"key":"comment","value":"MGI:MGI:101802  RO:0002264 GO:0032496 MGI:MGI:3784647|PMID:18305483 ECO:0000315 MGI:MGI:3038377  2010-01-12 MGI  creation-date\u003d2008-07-28|modification-date\u003d2010-01-12|comment\u003dIn a model of severe  but not completely lethal lipopolysaccharide (LPS) challenge9  we show that PAR1 deficiency protects mice from lethality. PAR1 deficiency attenuated broadly inflammatory parameters 18 h after LPS challenge|contributor-id\u003dhttps://orcid.org/0000-0003-2689-5511|contributor-id\u003dhttps://orcid.org/0000-0003-3394-9805"}]},{"subject":"gomodel:MGI_MGI_101802/3ffb1b6e-b838-4983-899e-1fee512d0613","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:MGI_MGI_101802/fca4bd50-d4c9-4221-a7f6-4cbd47f28b53","annotations":[{"key":"evidence","value":"gomodel:MGI_MGI_101802/70d7e4b4-e878-463d-96b0-9053c05bb9f1","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7476-6306"},{"key":"date","value":"2010-05-03"},{"key":"dc:created","value":"2010-05-03"},{"key":"dc:dateAccepted","value":"2022-03-28"},{"key":"providedBy","value":"http://informatics.jax.org"},{"key":"comment","value":"MGI:MGI:101802  RO:0002264 GO:0070493 MGI:MGI:3810206|PMID:18398001 ECO:0000316 MGI:MGI:88380  2010-05-03 MGI  creation-date\u003d2010-05-03|modification-date\u003d2010-05-03|comment\u003danatomy vibrissa follicle ; MA:0002910|comment\u003dcell type primary cell line cell ; CL:0000001|contributor-id\u003dhttps://orcid.org/0000-0001-7476-6306"}]},{"subject":"gomodel:MGI_MGI_101802/1c2985be-a111-4583-96fa-cc78057da176","property":"RO:0012003","property-label":"RO:0012003","object":"gomodel:MGI_MGI_101802/5cd4e486-42d5-4a7e-a02a-139f5290f71c","annotations":[{"key":"evidence","value":"gomodel:MGI_MGI_101802/caaa3300-6e04-46cf-9275-301d15a989f9","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0003-3394-9805"},{"key":"date","value":"2008-07-28"},{"key":"dc:created","value":"2008-07-28"},{"key":"dc:dateAccepted","value":"2022-03-28"},{"key":"providedBy","value":"http://informatics.jax.org"},{"key":"comment","value":"MGI:MGI:101802  RO:0002264 GO:0048873 MGI:MGI:3784647|PMID:18305483 ECO:0000315 MGI:MGI:3038377  2008-07-28 MGI BFO:0000066(EMAPA:35523),RO:0012003(CL:0000451) creation-date\u003d2008-07-28|modification-date\u003d2008-07-28|comment\u003danatomy lymph node;MA:0000139|comment\u003dcell type dendritic cell;CL:0000451 primary cell line cell;CL:0000001|contributor-id\u003dhttps://orcid.org/0000-0003-3394-9805"}]}],"annotations":[{"key":"state","value":"production"},{"key":"contributor","value":"https://orcid.org/0000-0001-7476-6306"},{"key":"contributor","value":"https://orcid.org/0000-0003-2689-5511"},{"key":"contributor","value":"https://orcid.org/0000-0003-3394-9805"},{"key":"date","value":"2023-07-20"},{"key":"title","value":"F2r (MGI:MGI:101802)"},{"key":"dc:created","value":"2008-07-28"},{"key":"dc:dateAccepted","value":"2022-03-28"},{"key":"providedBy","value":"http://informatics.jax.org"},{"key":"comment","value":"Automated change 2023-07-20: GO:0014068 replaced by GO:0051897"},{"key":"https://w3id.org/biolink/vocab/in_taxon","value":"NCBITaxon:10090","value-type":"IRI"}]}