{"id":"gomodel:684b6c8100004263","individuals":[{"id":"gomodel:684b6c8100004263/68fac5ed00000328","type":[{"type":"class","id":"GO:0032374","label":"regulation of cholesterol transport"}],"root-type":[{"type":"class","id":"GO:0008150","label":"biological_process"}],"annotations":[{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2025-10-27"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"}]},{"id":"gomodel:684b6c8100004263/68fac5ed00000329","type":[{"type":"class","id":"ECO:0000269","label":"experimental evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:35518199"},{"key":"contributor","value":"https://orcid.org/0000-0001-8769-177X"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2026-06-29"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"id":"gomodel:684b6c8100004263/68fac5ed00000352","type":[{"type":"class","id":"CHEBI:18303","label":"phosphatidyl-L-serine"}],"root-type":[{"type":"class","id":"CHEBI:24431","label":"chemical entity"}],"annotations":[{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2025-10-27"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"}]},{"id":"gomodel:684b6c8100004263/68fac5ed00000353","type":[{"type":"class","id":"GO:0009898","label":"cytoplasmic side of plasma membrane"}],"root-type":[{"type":"class","id":"UBERON:0001062","label":"anatomical entity"},{"type":"class","id":"GO:0110165","label":"cellular anatomical structure"},{"type":"class","id":"GO:0005575","label":"cellular_component"}],"annotations":[{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2025-10-27"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"}]},{"id":"gomodel:684b6c8100004263/68fac5ed00000354","type":[{"type":"class","id":"ECO:0000269","label":"experimental evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:35518199"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2025-10-27"}]},{"id":"gomodel:684b6c8100004263/68fac5ed00000355","type":[{"type":"class","id":"CHEBI:18303","label":"phosphatidyl-L-serine"}],"root-type":[{"type":"class","id":"CHEBI:24431","label":"chemical entity"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2025-10-27"}]},{"id":"gomodel:684b6c8100004263/68fac5ed00000356","type":[{"type":"class","id":"GO:0098554","label":"cytoplasmic side of endoplasmic reticulum membrane"}],"root-type":[{"type":"class","id":"UBERON:0001062","label":"anatomical entity"},{"type":"class","id":"GO:0110165","label":"cellular anatomical structure"},{"type":"class","id":"GO:0005575","label":"cellular_component"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-10-27"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"id":"gomodel:684b6c8100004263/68fac5ed00000357","type":[{"type":"class","id":"ECO:0000269","label":"experimental evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-10-27"},{"key":"source","value":"PMID:35518199"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"id":"gomodel:684b6c8100004263/68fac5ed00000358","type":[{"type":"class","id":"ECO:0000269","label":"experimental evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2025-10-27"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"source","value":"PMID:35518199"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"with","value":"ManualassertioninferredfromsequencesimilarityUniProtKB:Q9BZF3"}]},{"id":"gomodel:684b6c8100004263/68fac5ed00000360","type":[{"type":"class","id":"ECO:0000269","label":"experimental evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2025-10-27"},{"key":"with","value":"ManualassertioninferredfromsequencesimilarityUniProtKB:Q9BZF3"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"source","value":"PMID:35518199"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004281","type":[{"type":"class","id":"GO:0160270","label":"phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity"}],"root-type":[{"type":"class","id":"GO:0003674","label":"molecular_function"},{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"date","value":"2025-10-27"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004282","type":[{"type":"class","id":"UniProtKB:Q9BZF3","label":"OSBPL6 Hsap"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"},{"type":"class","id":"CHEBI:36080","label":"protein"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2025-06-26"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004284","type":[{"type":"class","id":"GO:0140268","label":"endoplasmic reticulum-plasma membrane contact site"}],"root-type":[{"type":"class","id":"UBERON:0001062","label":"anatomical entity"},{"type":"class","id":"GO:0110165","label":"cellular anatomical structure"},{"type":"class","id":"GO:0005575","label":"cellular_component"}],"annotations":[{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-06-26"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004285","type":[{"type":"class","id":"ECO:0000250","label":"sequence similarity evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"GO_REF:0000024"},{"key":"date","value":"2025-10-27"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"contributor","value":"https://orcid.org/0000-0001-8769-177X"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"with","value":"MGI:2139014"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004287","type":[{"type":"class","id":"ECO:0000250","label":"sequence similarity evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"source","value":"GO_REF:0000024"},{"key":"contributor","value":"https://orcid.org/0000-0001-8769-177X"},{"key":"date","value":"2025-10-27"},{"key":"with","value":"MGI:2139014"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004292","type":[{"type":"class","id":"CHEBI:58178","label":"1-phosphatidyl-1D-myo-inositol 4-phosphate(3-)"}],"root-type":[{"type":"class","id":"CHEBI:24431","label":"chemical entity"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2025-06-26"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004293","type":[{"type":"class","id":"GO:0009898","label":"cytoplasmic side of plasma membrane"}],"root-type":[{"type":"class","id":"UBERON:0001062","label":"anatomical entity"},{"type":"class","id":"GO:0110165","label":"cellular anatomical structure"},{"type":"class","id":"GO:0005575","label":"cellular_component"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2025-06-26"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004294","type":[{"type":"class","id":"ECO:0000269","label":"experimental evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"source","value":"PMID:30028970"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2025-06-26"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004297","type":[{"type":"class","id":"ECO:0000269","label":"experimental evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"source","value":"PMID:30028970"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-06-26"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004298","type":[{"type":"class","id":"CHEBI:58178","label":"1-phosphatidyl-1D-myo-inositol 4-phosphate(3-)"}],"root-type":[{"type":"class","id":"CHEBI:24431","label":"chemical entity"}],"annotations":[{"key":"date","value":"2025-06-26"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004299","type":[{"type":"class","id":"GO:0098554","label":"cytoplasmic side of endoplasmic reticulum membrane"}],"root-type":[{"type":"class","id":"UBERON:0001062","label":"anatomical entity"},{"type":"class","id":"GO:0110165","label":"cellular anatomical structure"},{"type":"class","id":"GO:0005575","label":"cellular_component"}],"annotations":[{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2025-06-26"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004300","type":[{"type":"class","id":"ECO:0000269","label":"experimental evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:30028970"},{"key":"date","value":"2025-06-26"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"}]},{"id":"gomodel:684b6c8100004263/684b6c8100004301","type":[{"type":"class","id":"ECO:0000269","label":"experimental evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"source","value":"PMID:30028970"},{"key":"date","value":"2025-06-26"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"id":"gomodel:684b6c8100004263/6870555700001612","type":[{"type":"class","id":"UBERON:0000955","label":"brain"}],"root-type":[{"type":"class","id":"UBERON:0001062","label":"anatomical entity"}],"annotations":[{"key":"date","value":"2025-10-27"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"id":"gomodel:684b6c8100004263/6870555700001613","type":[{"type":"class","id":"ECO:0000250","label":"sequence similarity evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"source","value":"GO_REF:0000024"},{"key":"with","value":"MGI:2139014"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"date","value":"2025-10-27"},{"key":"contributor","value":"https://orcid.org/0000-0001-8769-177X"}]},{"id":"gomodel:684b6c8100004263/689e7a5d00004044","type":[{"type":"class","id":"GO:0120010","label":"intermembrane phospholipid transfer"}],"root-type":[{"type":"class","id":"GO:0008150","label":"biological_process"}],"annotations":[{"key":"date","value":"2025-08-24"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"id":"gomodel:684b6c8100004263/689e7a5d00004045","type":[{"type":"class","id":"ECO:0000250","label":"sequence similarity evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2025-10-27"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"with","value":"MGI:2139014"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"contributor","value":"https://orcid.org/0000-0001-8769-177X"},{"key":"source","value":"GO_REF:0000024"},{"key":"providedBy","value":"https://www.uniprot.org"}]}],"facts":[{"subject":"gomodel:684b6c8100004263/68fac5ed00000352","property":"RO:0001025","property-label":"RO:0001025","object":"gomodel:684b6c8100004263/68fac5ed00000353","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/68fac5ed00000354","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-10-27"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/684b6c8100004281","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:684b6c8100004263/689e7a5d00004044","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/689e7a5d00004045","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-08-24"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/684b6c8100004281","property":"BFO:0000066","property-label":"BFO:0000066","object":"gomodel:684b6c8100004263/684b6c8100004284","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/684b6c8100004287","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-06-26"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/684b6c8100004281","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:684b6c8100004263/68fac5ed00000355","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/68fac5ed00000358","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-10-27"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/684b6c8100004298","property":"RO:0001025","property-label":"RO:0001025","object":"gomodel:684b6c8100004263/684b6c8100004299","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/684b6c8100004300","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-06-26"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/684b6c8100004281","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:684b6c8100004263/684b6c8100004282","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/684b6c8100004285","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-06-26"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/684b6c8100004281","property":"RO:0002234","property-label":"RO:0002234","object":"gomodel:684b6c8100004263/684b6c8100004298","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/684b6c8100004301","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-06-26"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/68fac5ed00000355","property":"RO:0001025","property-label":"RO:0001025","object":"gomodel:684b6c8100004263/68fac5ed00000356","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/68fac5ed00000357","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-10-27"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/689e7a5d00004044","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:684b6c8100004263/68fac5ed00000328","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/68fac5ed00000329","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-10-27"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/684b6c8100004284","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:684b6c8100004263/6870555700001612","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/6870555700001613","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-07-16"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/684b6c8100004281","property":"RO:0002234","property-label":"RO:0002234","object":"gomodel:684b6c8100004263/68fac5ed00000352","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/68fac5ed00000360","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-10-27"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/684b6c8100004281","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:684b6c8100004263/684b6c8100004292","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/684b6c8100004297","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-06-26"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]},{"subject":"gomodel:684b6c8100004263/684b6c8100004292","property":"RO:0001025","property-label":"RO:0001025","object":"gomodel:684b6c8100004263/684b6c8100004293","annotations":[{"key":"evidence","value":"gomodel:684b6c8100004263/684b6c8100004294","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2025-06-26"},{"key":"providedBy","value":"https://holthuis-lab-uos.de"}]}],"annotations":[{"key":"state","value":"production"},{"key":"contributor","value":"https://orcid.org/0000-0001-8769-177X"},{"key":"contributor","value":"https://orcid.org/0009-0002-7487-1936"},{"key":"date","value":"2026-06-29"},{"key":"title","value":"PI4P transfer from PM to ER by OSBPL6 "},{"key":"providedBy","value":"https://holthuis-lab-uos.de"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"https://w3id.org/biolink/vocab/in_taxon","value":"NCBITaxon:9606","value-type":"IRI"}]}