{"id":"gomodel:666b894f00001546","individuals":[{"id":"gomodel:666b894f00001546/666b894f00001547","type":[{"type":"class","id":"GO:0004993","label":"G protein-coupled serotonin receptor activity"}],"root-type":[{"type":"class","id":"GO:0003674","label":"molecular_function"},{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"date","value":"2024-06-20"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001548","type":[{"type":"class","id":"GO:0005886","label":"plasma membrane"}],"root-type":[{"type":"class","id":"UBERON:0001062","label":"anatomical entity"},{"type":"class","id":"GO:0110165","label":"cellular anatomical structure"},{"type":"class","id":"GO:0005575","label":"cellular_component"}],"annotations":[{"key":"date","value":"2024-06-20"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001551","type":[{"type":"class","id":"GO:0003925","label":"G protein activity"}],"root-type":[{"type":"class","id":"GO:0003674","label":"molecular_function"},{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-20"}]},{"id":"gomodel:666b894f00001546/666b894f00001552","type":[{"type":"class","id":"GO:0009898","label":"cytoplasmic side of plasma membrane"}],"root-type":[{"type":"class","id":"UBERON:0001062","label":"anatomical entity"},{"type":"class","id":"GO:0110165","label":"cellular anatomical structure"},{"type":"class","id":"GO:0005575","label":"cellular_component"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-20"}]},{"id":"gomodel:666b894f00001546/666b894f00001553","type":[{"type":"class","id":"GO:0004016","label":"adenylate cyclase activity"}],"root-type":[{"type":"class","id":"GO:0003674","label":"molecular_function"},{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"date","value":"2024-06-20"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001559","type":[{"type":"class","id":"CHEBI:17489","label":"3\u0027,5\u0027-cyclic AMP"}],"root-type":[{"type":"class","id":"CHEBI:24431","label":"chemical entity"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"date","value":"2024-06-20"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001560","type":[{"type":"class","id":"CHEBI:350546","label":"serotonin(1+)"}],"root-type":[{"type":"class","id":"CHEBI:24431","label":"chemical entity"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-20"}]},{"id":"gomodel:666b894f00001546/666b894f00001562","type":[{"type":"class","id":"UniProtKB:Q13639","label":"HTR4 Hsap"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"},{"type":"class","id":"CHEBI:36080","label":"protein"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"date","value":"2024-06-25"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001563","type":[{"type":"class","id":"UniProtKB:P63092","label":"GNAS Hsap"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"},{"type":"class","id":"CHEBI:36080","label":"protein"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"date","value":"2025-04-10"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001564","type":[{"type":"class","id":"UniProtKB:O43306","label":"ADCY6 Hsap"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"},{"type":"class","id":"CHEBI:36080","label":"protein"}],"annotations":[{"key":"date","value":"2024-06-20"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001568","type":[{"type":"class","id":"GO:0007192","label":"adenylate cyclase-activating serotonin receptor signaling pathway"}],"root-type":[{"type":"class","id":"GO:0008150","label":"biological_process"}],"annotations":[{"key":"date","value":"2024-06-25"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001569","type":[{"type":"class","id":"GO:0007192","label":"adenylate cyclase-activating serotonin receptor signaling pathway"}],"root-type":[{"type":"class","id":"GO:0008150","label":"biological_process"}],"annotations":[{"key":"date","value":"2024-06-25"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"id":"gomodel:666b894f00001546/666b894f00001570","type":[{"type":"class","id":"GO:0007192","label":"adenylate cyclase-activating serotonin receptor signaling pathway"}],"root-type":[{"type":"class","id":"GO:0008150","label":"biological_process"}],"annotations":[{"key":"date","value":"2024-06-25"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001575","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"date","value":"2024-06-20"},{"key":"source","value":"PMID:17110384"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001576","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2024-06-20"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"source","value":"PMID:17110384"}]},{"id":"gomodel:666b894f00001546/666b894f00001578","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-20"},{"key":"source","value":"PMID:17916776"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"id":"gomodel:666b894f00001546/666b894f00001579","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"source","value":"PMID:23842570"},{"key":"date","value":"2024-06-20"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"id":"gomodel:666b894f00001546/666b894f00001581","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:17916776"},{"key":"date","value":"2024-06-20"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001582","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:23842570"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"date","value":"2024-06-20"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001583","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2024-06-20"},{"key":"source","value":"PMID:17110384"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00001584","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"PMID:12135370"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"date","value":"2024-06-20"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/666b894f00002015","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"source","value":"PMID:35714614"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"date","value":"2024-06-25"}]},{"id":"gomodel:666b894f00001546/666b894f00002016","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"source","value":"PMID:35714614"},{"key":"date","value":"2024-06-25"}]},{"id":"gomodel:666b894f00001546/666b894f00002017","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-25"},{"key":"source","value":"PMID:22448645"}]},{"id":"gomodel:666b894f00001546/667dfe8d00000107","type":[{"type":"class","id":"UniProtKB:P63092","label":"GNAS Hsap"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"},{"type":"class","id":"CHEBI:36080","label":"protein"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2025-04-10"}]},{"id":"gomodel:666b894f00001546/667dfe8d00000108","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2024-06-28"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"source","value":"PMID:35714614"}]},{"id":"gomodel:666b894f00001546/667dfe8d00000754","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"date","value":"2024-07-01"},{"key":"source","value":"PMID:35714614"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/667dfe8d00000755","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2024-07-01"},{"key":"source","value":"PMID:35714614"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"}]},{"id":"gomodel:666b894f00001546/667dfe8d00000756","type":[{"type":"class","id":"ECO:0000314","label":"direct assay evidence used in manual assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2024-07-01"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"source","value":"PMID:17110384"}]}],"facts":[{"subject":"gomodel:666b894f00001546/666b894f00001553","property":"RO:0002234","property-label":"RO:0002234","object":"gomodel:666b894f00001546/666b894f00001559","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/666b894f00001581","value-type":"IRI"},{"key":"evidence","value":"gomodel:666b894f00001546/666b894f00001582","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-20"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001547","property":"BFO:0000066","property-label":"BFO:0000066","object":"gomodel:666b894f00001546/666b894f00001548","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/666b894f00002017","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-25"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001551","property":"RO:0002629","property-label":"RO:0002629","object":"gomodel:666b894f00001546/666b894f00001553","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/667dfe8d00000756","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-07-01"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001551","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:666b894f00001546/666b894f00001569","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/666b894f00001576","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-20"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001551","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:666b894f00001546/666b894f00001563","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/666b894f00001575","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-20"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001551","property":"BFO:0000066","property-label":"BFO:0000066","object":"gomodel:666b894f00001546/666b894f00001552","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/666b894f00001584","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-20"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001547","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:666b894f00001546/666b894f00001568","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/666b894f00002016","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-25"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001553","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:666b894f00001546/666b894f00001570","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/666b894f00001583","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-20"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001547","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:666b894f00001546/666b894f00001562","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/666b894f00002015","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-25"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001547","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:666b894f00001546/667dfe8d00000107","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/667dfe8d00000108","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-28"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001547","property":"RO:0002629","property-label":"RO:0002629","object":"gomodel:666b894f00001546/666b894f00001551","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/667dfe8d00000755","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-07-01"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001553","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:666b894f00001546/666b894f00001564","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/666b894f00001578","value-type":"IRI"},{"key":"evidence","value":"gomodel:666b894f00001546/666b894f00001579","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-06-20"},{"key":"providedBy","value":"https://www.uniprot.org"}]},{"subject":"gomodel:666b894f00001546/666b894f00001560","property":"RO:0012005","property-label":"RO:0012005","object":"gomodel:666b894f00001546/666b894f00001547","annotations":[{"key":"evidence","value":"gomodel:666b894f00001546/667dfe8d00000754","value-type":"IRI"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2024-07-01"},{"key":"providedBy","value":"https://www.uniprot.org"}]}],"annotations":[{"key":"state","value":"production"},{"key":"contributor","value":"https://orcid.org/0000-0001-7299-6685"},{"key":"date","value":"2025-04-10"},{"key":"title","value":"HTR4-mediated serotonin signaling G-alpha-s (\"stimulatory\", activating adenylate cyclase) (Human)."},{"key":"providedBy","value":"https://www.uniprot.org"},{"key":"wasDerivedFrom","value":"gomodel:5df932e000002904","value-type":"IRI"},{"key":"https://w3id.org/biolink/vocab/in_taxon","value":"NCBITaxon:9606","value-type":"IRI"}]}