{"id":"gomodel:R-HSA-168927","individuals":[{"id":"gomodel:R-HSA-166170_R-HSA-168929","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-166170","label":"TRIF"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"},{"type":"class","id":"CHEBI:36080","label":"protein"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Protein12741","value-type":"IRI"},{"key":"rdfs:label","value":"TRIF"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Protein"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-166170"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"comment","value":"located_in cytosol"}]},{"id":"gomodel:R-HSA-167985_R-HSA-168929","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-167985","label":"viral dsRNA :TLR3"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"comment","value":"located_in endosome membrane"},{"key":"rdfs:label","value":"viral dsRNA :TLR3"},{"key":"providedBy","value":"https://reactome.org"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-167985"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex2935","value-type":"IRI"},{"key":"date","value":"2023-06-21"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:R-HSA-168113_R-HSA-9014343","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-168113","label":"IKK complex"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-168113"},{"key":"rdfs:label","value":"IKK complex"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex2606","value-type":"IRI"},{"key":"comment","value":"located_in cytosol"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:R-HSA-168651_R-HSA-168930","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-168651","label":"RIP1"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"},{"type":"class","id":"CHEBI:36080","label":"protein"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Protein3090","value-type":"IRI"},{"key":"comment","value":"located_in cytosol"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-168651"},{"key":"date","value":"2023-06-21"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Protein"},{"key":"rdfs:label","value":"RIP1"}]},{"id":"gomodel:R-HSA-168907_R-HSA-168929","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-168907","label":"viral dsRNA:TLR3:TRIF"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"comment","value":"located_in endosome membrane"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex2936","value-type":"IRI"},{"key":"date","value":"2023-06-21"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-168907"},{"key":"providedBy","value":"https://reactome.org"},{"key":"rdfs:label","value":"viral dsRNA:TLR3:TRIF"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"}]},{"id":"gomodel:R-HSA-168907_R-HSA-168930","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-168907","label":"viral dsRNA:TLR3:TRIF"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-168907"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex2936","value-type":"IRI"},{"key":"providedBy","value":"https://reactome.org"},{"key":"rdfs:label","value":"viral dsRNA:TLR3:TRIF"},{"key":"comment","value":"located_in endosome membrane"},{"key":"date","value":"2023-06-21"}]},{"id":"gomodel:R-HSA-168912_R-HSA-168915","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-168912","label":"RIP1:TRIF:activated TLR4"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"comment","value":"located_in endosome membrane"},{"key":"rdfs:label","value":"RIP1:TRIF:activated TLR4"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-168912"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex4915","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"}]},{"id":"gomodel:R-HSA-168915","type":[{"type":"class","id":"GO:0004842","label":"ubiquitin-protein transferase activity"}],"root-type":[{"type":"class","id":"GO:0003674","label":"molecular_function"},{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"rdfs:label","value":"K63-linked ubiquitination of RIP1 bound to the activated TLR complex"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.BiochemicalReaction"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-168915"},{"key":"comment","value":"reaction from external pathway R-HSA-937041"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#BiochemicalReaction3437","value-type":"IRI"}]},{"id":"gomodel:R-HSA-168929","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"root-type":[{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"rdfs:label","value":"Viral dsRNA:TLR3 recruits TRIF (TICAM1)"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.BiochemicalReaction"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#BiochemicalReaction3347","value-type":"IRI"},{"key":"comment","value":"reaction from external pathway R-HSA-168164"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-168929"}]},{"id":"gomodel:R-HSA-168930","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"root-type":[{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-168930"},{"key":"providedBy","value":"https://reactome.org"},{"key":"rdfs:label","value":"Viral dsRNA:TLR3:TRIF complex recruits RIP1"},{"key":"date","value":"2023-06-21"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.BiochemicalReaction"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#BiochemicalReaction3358","value-type":"IRI"}]},{"id":"gomodel:R-HSA-177649_R-HSA-168930","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-177649","label":"viral dsRNA:TLR3:TRIF:RIP1"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"rdfs:label","value":"viral dsRNA:TLR3:TRIF:RIP1"},{"key":"date","value":"2023-06-21"},{"key":"comment","value":"located_in endosome membrane"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-177649"},{"key":"providedBy","value":"https://reactome.org"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex4824","value-type":"IRI"}]},{"id":"gomodel:R-HSA-177649_R-HSA-9014342","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-177649","label":"viral dsRNA:TLR3:TRIF:RIP1"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex4824","value-type":"IRI"},{"key":"providedBy","value":"https://reactome.org"},{"key":"rdfs:label","value":"viral dsRNA:TLR3:TRIF:RIP1"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"},{"key":"date","value":"2023-06-21"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-177649"},{"key":"comment","value":"located_in endosome membrane"}]},{"id":"gomodel:R-HSA-2569050_R-HSA-168915_controller","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-2569050","label":"RIP1 ubiqutin ligases"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-2569050"},{"key":"date","value":"2023-06-21"},{"key":"rdfs:label","value":"RIP1 ubiqutin ligases"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex4826","value-type":"IRI"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"comment","value":"located_in cytosol"}]},{"id":"gomodel:R-HSA-2569050_R-HSA-9014342_controller","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-2569050","label":"RIP1 ubiqutin ligases"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-2569050"},{"key":"rdfs:label","value":"RIP1 ubiqutin ligases"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex4826","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"comment","value":"located_in cytosol"},{"key":"providedBy","value":"https://reactome.org"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"}]},{"id":"gomodel:R-HSA-450152_R-HSA-168915","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-450152","label":"K63polyUb"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"},{"type":"class","id":"CHEBI:36080","label":"protein"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"rdfs:label","value":"K63polyUb"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#PhysicalEntity254","value-type":"IRI"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-450152"},{"key":"comment","value":"located_in cytosol"},{"key":"date","value":"2023-06-21"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.PhysicalEntity"}]},{"id":"gomodel:R-HSA-450152_R-HSA-9014342","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-450152","label":"K63polyUb"}],"root-type":[{"type":"class","id":"CHEBI:33695","label":"information biomacromolecule"},{"type":"class","id":"CHEBI:24431","label":"chemical entity"},{"type":"class","id":"CHEBI:36080","label":"protein"}],"annotations":[{"key":"skos:note","value":"org.biopax.paxtools.model.level3.PhysicalEntity"},{"key":"rdfs:label","value":"K63polyUb"},{"key":"comment","value":"located_in cytosol"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#PhysicalEntity254","value-type":"IRI"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-450152"},{"key":"date","value":"2023-06-21"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:R-HSA-9014341_R-HSA-9014343","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-9014341","label":"viral dsRNA:TLR3:TICAM1:K63pUb-RIP1:IKK complex"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex4831","value-type":"IRI"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"rdfs:label","value":"viral dsRNA:TLR3:TICAM1:K63pUb-RIP1:IKK complex"},{"key":"comment","value":"located_in endosome membrane"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-9014341"}]},{"id":"gomodel:R-HSA-9014342","type":[{"type":"class","id":"GO:0004842","label":"ubiquitin-protein transferase activity"}],"root-type":[{"type":"class","id":"GO:0003674","label":"molecular_function"},{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-9014342"},{"key":"rdfs:label","value":"K63-linked ubiquitination of RIP1 bound to the activated TLR complex"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.BiochemicalReaction"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#BiochemicalReaction3359","value-type":"IRI"}]},{"id":"gomodel:R-HSA-9014343","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"root-type":[{"type":"class","id":"obo:go/extensions/reacto.owl#molecular_event","label":"Molecular Event"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-9014343"},{"key":"providedBy","value":"https://reactome.org"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.BiochemicalReaction"},{"key":"rdfs:label","value":"Nemo subunit of IKK complex binds polyubiquinated RIP1"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#BiochemicalReaction3360","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:R-HSA-9014344_R-HSA-9014342","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-9014344","label":"activated TLR3:TICAM1:K63pUb-RIP1"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex4825","value-type":"IRI"},{"key":"comment","value":"located_in endosome membrane"},{"key":"date","value":"2023-06-21"},{"key":"rdfs:label","value":"activated TLR3:TICAM1:K63pUb-RIP1"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-9014344"}]},{"id":"gomodel:R-HSA-9014344_R-HSA-9014343","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-9014344","label":"activated TLR3:TICAM1:K63pUb-RIP1"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"located_in endosome membrane"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex4825","value-type":"IRI"},{"key":"date","value":"2023-06-21"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-9014344"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"},{"key":"rdfs:label","value":"activated TLR3:TICAM1:K63pUb-RIP1"}]},{"id":"gomodel:R-HSA-937016_R-HSA-168915","type":[{"type":"class","id":"obo:go/extensions/reacto.owl#REACTO_R-HSA-937016","label":"activated TLR4:TRIF:K63pUb-RIP1"}],"root-type":[{"type":"class","id":"GO:0005575","label":"cellular_component"},{"type":"class","id":"GO:0032991","label":"protein-containing complex"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Complex"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"Reactome:R-HSA-937016"},{"key":"rdfs:label","value":"activated TLR4:TRIF:K63pUb-RIP1"},{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"},{"key":"skos:exactMatch","value":"http://www.reactome.org/biopax/84/48887#Complex4916","value-type":"IRI"},{"key":"comment","value":"located_in endosome membrane"}]},{"id":"gomodel:ev_w_id_R-HSA-168915_BFO_0000066_reaction_R-HSA-168915_location_lociGO_0005829_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"source","value":"Reactome:R-HSA-168927"}]},{"id":"gomodel:ev_w_id_R-HSA-168915_RO_0002233_R-HSA-168912_R-HSA-168915_Reactome_R-HSA-168915","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168915"}]},{"id":"gomodel:ev_w_id_R-HSA-168915_RO_0002233_R-HSA-168912_R-HSA-168915_Reactome_R-HSA-937041","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-937041"},{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:ev_w_id_R-HSA-168915_RO_0002233_R-HSA-450152_R-HSA-168915_Reactome_R-HSA-168915","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168915"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:ev_w_id_R-HSA-168915_RO_0002233_R-HSA-450152_R-HSA-168915_Reactome_R-HSA-937041","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"source","value":"Reactome:R-HSA-937041"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"}]},{"id":"gomodel:ev_w_id_R-HSA-168915_RO_0002234_R-HSA-937016_R-HSA-168915_Reactome_R-HSA-168915","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-168915"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:ev_w_id_R-HSA-168915_RO_0002234_R-HSA-937016_R-HSA-168915_Reactome_R-HSA-937041","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-937041"}]},{"id":"gomodel:ev_w_id_R-HSA-168915_RO_0002333_R-HSA-2569050_R-HSA-168915_controller_Reactome_R-HSA-168915","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168915"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:ev_w_id_R-HSA-168915_RO_0002333_R-HSA-2569050_R-HSA-168915_controller_Reactome_R-HSA-937041","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"source","value":"Reactome:R-HSA-937041"},{"key":"date","value":"2023-06-21"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:ev_w_id_R-HSA-168915_RO_0002411_R-HSA-9014343_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168927"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:ev_w_id_R-HSA-168929_RO_0002233_R-HSA-166170_R-HSA-168929_Reactome_R-HSA-168164","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-168164"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:ev_w_id_R-HSA-168929_RO_0002233_R-HSA-166170_R-HSA-168929_Reactome_R-HSA-168929","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-168929"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:ev_w_id_R-HSA-168929_RO_0002233_R-HSA-167985_R-HSA-168929_Reactome_R-HSA-168164","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168164"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:ev_w_id_R-HSA-168929_RO_0002233_R-HSA-167985_R-HSA-168929_Reactome_R-HSA-168929","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168929"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:ev_w_id_R-HSA-168929_RO_0002234_R-HSA-168907_R-HSA-168929_Reactome_R-HSA-168164","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"source","value":"Reactome:R-HSA-168164"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:ev_w_id_R-HSA-168929_RO_0002234_R-HSA-168907_R-HSA-168929_Reactome_R-HSA-168929","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168929"}]},{"id":"gomodel:ev_w_id_R-HSA-168929_RO_0002411_R-HSA-168930_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"source","value":"Reactome:R-HSA-168927"},{"key":"date","value":"2023-06-21"}]},{"id":"gomodel:ev_w_id_R-HSA-168930_RO_0002233_R-HSA-168651_R-HSA-168930_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-168927"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:ev_w_id_R-HSA-168930_RO_0002233_R-HSA-168651_R-HSA-168930_Reactome_R-HSA-168930","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"source","value":"Reactome:R-HSA-168930"}]},{"id":"gomodel:ev_w_id_R-HSA-168930_RO_0002233_R-HSA-168907_R-HSA-168930_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168927"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:ev_w_id_R-HSA-168930_RO_0002233_R-HSA-168907_R-HSA-168930_Reactome_R-HSA-168930","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"source","value":"Reactome:R-HSA-168930"}]},{"id":"gomodel:ev_w_id_R-HSA-168930_RO_0002234_R-HSA-177649_R-HSA-168930_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"source","value":"Reactome:R-HSA-168927"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"}]},{"id":"gomodel:ev_w_id_R-HSA-168930_RO_0002234_R-HSA-177649_R-HSA-168930_Reactome_R-HSA-168930","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"source","value":"Reactome:R-HSA-168930"},{"key":"date","value":"2023-06-21"}]},{"id":"gomodel:ev_w_id_R-HSA-168930_RO_0002413_R-HSA-9014342_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000363","label":"computational inference used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168927"}]},{"id":"gomodel:ev_w_id_R-HSA-9014342_BFO_0000066_reaction_R-HSA-9014342_location_lociGO_0005829_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"source","value":"Reactome:R-HSA-168927"}]},{"id":"gomodel:ev_w_id_R-HSA-9014342_RO_0002233_R-HSA-177649_R-HSA-9014342_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-168927"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:ev_w_id_R-HSA-9014342_RO_0002233_R-HSA-177649_R-HSA-9014342_Reactome_R-HSA-9014342","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-9014342"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"}]},{"id":"gomodel:ev_w_id_R-HSA-9014342_RO_0002233_R-HSA-450152_R-HSA-9014342_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-168927"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:ev_w_id_R-HSA-9014342_RO_0002233_R-HSA-450152_R-HSA-9014342_Reactome_R-HSA-9014342","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"source","value":"Reactome:R-HSA-9014342"},{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"}]},{"id":"gomodel:ev_w_id_R-HSA-9014342_RO_0002234_R-HSA-9014344_R-HSA-9014342_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-168927"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:ev_w_id_R-HSA-9014342_RO_0002234_R-HSA-9014344_R-HSA-9014342_Reactome_R-HSA-9014342","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-9014342"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:ev_w_id_R-HSA-9014342_RO_0002333_R-HSA-2569050_R-HSA-9014342_controller_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-168927"},{"key":"date","value":"2023-06-21"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:ev_w_id_R-HSA-9014342_RO_0002333_R-HSA-2569050_R-HSA-9014342_controller_Reactome_R-HSA-9014342","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"source","value":"Reactome:R-HSA-9014342"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"}]},{"id":"gomodel:ev_w_id_R-HSA-9014343_RO_0002233_R-HSA-168113_R-HSA-9014343_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168927"}]},{"id":"gomodel:ev_w_id_R-HSA-9014343_RO_0002233_R-HSA-168113_R-HSA-9014343_Reactome_R-HSA-9014343","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"source","value":"Reactome:R-HSA-9014343"}]},{"id":"gomodel:ev_w_id_R-HSA-9014343_RO_0002233_R-HSA-9014344_R-HSA-9014343_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168927"}]},{"id":"gomodel:ev_w_id_R-HSA-9014343_RO_0002233_R-HSA-9014344_R-HSA-9014343_Reactome_R-HSA-9014343","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-9014343"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:ev_w_id_R-HSA-9014343_RO_0002234_R-HSA-9014341_R-HSA-9014343_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"source","value":"Reactome:R-HSA-168927"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:ev_w_id_R-HSA-9014343_RO_0002234_R-HSA-9014341_R-HSA-9014343_Reactome_R-HSA-9014343","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"source","value":"Reactome:R-HSA-9014343"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:reaction_R-HSA-168915_location_lociGO_0005829","type":[{"type":"class","id":"GO:0005829","label":"cytosol"}],"root-type":[{"type":"class","id":"UBERON:0001062","label":"anatomical entity"},{"type":"class","id":"GO:0110165","label":"cellular anatomical structure"},{"type":"class","id":"GO:0005575","label":"cellular_component"}],"annotations":[{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"}]},{"id":"gomodel:reaction_R-HSA-9014342_location_lociGO_0005829","type":[{"type":"class","id":"GO:0005829","label":"cytosol"}],"root-type":[{"type":"class","id":"UBERON:0001062","label":"anatomical entity"},{"type":"class","id":"GO:0110165","label":"cellular anatomical structure"},{"type":"class","id":"GO:0005575","label":"cellular_component"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"}]},{"id":"gomodel:R-HSA-168927/R-HSA-168927","type":[{"type":"class","id":"GO:0002756","label":"MyD88-independent toll-like receptor signaling pathway"}],"root-type":[{"type":"class","id":"GO:0008150","label":"biological_process"}],"annotations":[{"key":"comment","value":"Receptor-interacting protein 1 (RIP1) mediates the activation of interferon-alpha/beta via intermediate activation of IKK/TBK1 or NFkB pathways."},{"key":"rdfs:label","value":"TICAM1, RIP1-mediated IKK complex recruitment"},{"key":"contributor","value":"Reviewed: Fitzgerald, Katherine A, 2012-11-13"},{"key":"date","value":"2023-06-21"},{"key":"contributor","value":"Reviewed: Gay, NJ, 2006-04-24 16:48:17"},{"key":"skos:note","value":"org.biopax.paxtools.model.level3.Pathway"},{"key":"http://www.geneontology.org/formats/oboInOwl#hasDbXref","value":"R-HSA-168927"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"contributor","value":"Edited: Shamovsky, V, 2009-12-16"},{"key":"providedBy","value":"https://reactome.org"},{"key":"skos:narrower","value":"gomodel:R-HSA-168164/R-HSA-168164","value-type":"IRI"},{"key":"contributor","value":"Authored: Luo, F, 2005-11-10 11:23:18"}]},{"id":"gomodel:ev_w_id_R-HSA-168930_BFO_0000050_R-HSA-168927/R-HSA-168927_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"source","value":"Reactome:R-HSA-168927"}]},{"id":"gomodel:ev_w_id_R-HSA-9014342_BFO_0000050_R-HSA-168927/R-HSA-168927_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"contributor","value":"GOC:reactome_curators"},{"key":"providedBy","value":"https://reactome.org"},{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168927"}]},{"id":"gomodel:ev_w_id_R-HSA-9014343_BFO_0000050_R-HSA-168927/R-HSA-168927_Reactome_R-HSA-168927","type":[{"type":"class","id":"ECO:0000313","label":"imported information used in automatic assertion"}],"root-type":[{"type":"class","id":"ECO:0000000","label":"evidence"}],"annotations":[{"key":"providedBy","value":"https://reactome.org"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"source","value":"Reactome:R-HSA-168927"}]}],"facts":[{"subject":"gomodel:R-HSA-168930","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:R-HSA-168927/R-HSA-168927","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168930_BFO_0000050_R-HSA-168927/R-HSA-168927_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-9014343","property":"RO:0002234","property-label":"RO:0002234","object":"gomodel:R-HSA-9014341_R-HSA-9014343","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014343_RO_0002234_R-HSA-9014341_R-HSA-9014343_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014343_RO_0002234_R-HSA-9014341_R-HSA-9014343_Reactome_R-HSA-9014343","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-9014342","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:R-HSA-168927/R-HSA-168927","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014342_BFO_0000050_R-HSA-168927/R-HSA-168927_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-168930","property":"RO:0002413","property-label":"RO:0002413","object":"gomodel:R-HSA-9014342","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168930_RO_0002413_R-HSA-9014342_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"},{"key":"comment","value":"Provides Input For Rule. The relation \u0027Viral dsRNA:TLR3:TRIF complex recruits RIP1\u0027 \u0027null\u0027 \u0027K63-linked ubiquitination of RIP1 bound to the activated TLR complex\u0027 was inferred because:\n reaction1 has an output that is an input of reaction 2. "}]},{"subject":"gomodel:R-HSA-168915","property":"RO:0002411","property-label":"RO:0002411","object":"gomodel:R-HSA-9014343","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168915_RO_0002411_R-HSA-9014343_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-9014343","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:R-HSA-9014344_R-HSA-9014343","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014343_RO_0002233_R-HSA-9014344_R-HSA-9014343_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014343_RO_0002233_R-HSA-9014344_R-HSA-9014343_Reactome_R-HSA-9014343","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-9014342","property":"RO:0002234","property-label":"RO:0002234","object":"gomodel:R-HSA-9014344_R-HSA-9014342","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014342_RO_0002234_R-HSA-9014344_R-HSA-9014342_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014342_RO_0002234_R-HSA-9014344_R-HSA-9014342_Reactome_R-HSA-9014342","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-9014343","property":"BFO:0000050","property-label":"BFO:0000050","object":"gomodel:R-HSA-168927/R-HSA-168927","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014343_BFO_0000050_R-HSA-168927/R-HSA-168927_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-168915","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:R-HSA-168912_R-HSA-168915","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168915_RO_0002233_R-HSA-168912_R-HSA-168915_Reactome_R-HSA-168915","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168915_RO_0002233_R-HSA-168912_R-HSA-168915_Reactome_R-HSA-937041","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-9014342","property":"BFO:0000066","property-label":"BFO:0000066","object":"gomodel:reaction_R-HSA-9014342_location_lociGO_0005829","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014342_BFO_0000066_reaction_R-HSA-9014342_location_lociGO_0005829_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"},{"key":"comment","value":"Occurs In Rule. This relation was asserted based on the location of the enabling molecule. "}]},{"subject":"gomodel:R-HSA-168929","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:R-HSA-166170_R-HSA-168929","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168929_RO_0002233_R-HSA-166170_R-HSA-168929_Reactome_R-HSA-168164","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168929_RO_0002233_R-HSA-166170_R-HSA-168929_Reactome_R-HSA-168929","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-9014342","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:R-HSA-177649_R-HSA-9014342","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014342_RO_0002233_R-HSA-177649_R-HSA-9014342_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014342_RO_0002233_R-HSA-177649_R-HSA-9014342_Reactome_R-HSA-9014342","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-168930","property":"RO:0002234","property-label":"RO:0002234","object":"gomodel:R-HSA-177649_R-HSA-168930","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168930_RO_0002234_R-HSA-177649_R-HSA-168930_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168930_RO_0002234_R-HSA-177649_R-HSA-168930_Reactome_R-HSA-168930","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-168915","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:R-HSA-2569050_R-HSA-168915_controller","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168915_RO_0002333_R-HSA-2569050_R-HSA-168915_controller_Reactome_R-HSA-168915","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168915_RO_0002333_R-HSA-2569050_R-HSA-168915_controller_Reactome_R-HSA-937041","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-168929","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:R-HSA-167985_R-HSA-168929","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168929_RO_0002233_R-HSA-167985_R-HSA-168929_Reactome_R-HSA-168164","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168929_RO_0002233_R-HSA-167985_R-HSA-168929_Reactome_R-HSA-168929","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-168929","property":"RO:0002234","property-label":"RO:0002234","object":"gomodel:R-HSA-168907_R-HSA-168929","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168929_RO_0002234_R-HSA-168907_R-HSA-168929_Reactome_R-HSA-168164","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168929_RO_0002234_R-HSA-168907_R-HSA-168929_Reactome_R-HSA-168929","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-9014342","property":"RO:0002333","property-label":"RO:0002333","object":"gomodel:R-HSA-2569050_R-HSA-9014342_controller","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014342_RO_0002333_R-HSA-2569050_R-HSA-9014342_controller_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014342_RO_0002333_R-HSA-2569050_R-HSA-9014342_controller_Reactome_R-HSA-9014342","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-9014343","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:R-HSA-168113_R-HSA-9014343","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014343_RO_0002233_R-HSA-168113_R-HSA-9014343_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014343_RO_0002233_R-HSA-168113_R-HSA-9014343_Reactome_R-HSA-9014343","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-168915","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:R-HSA-450152_R-HSA-168915","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168915_RO_0002233_R-HSA-450152_R-HSA-168915_Reactome_R-HSA-168915","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168915_RO_0002233_R-HSA-450152_R-HSA-168915_Reactome_R-HSA-937041","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-168929","property":"RO:0002411","property-label":"RO:0002411","object":"gomodel:R-HSA-168930","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168929_RO_0002411_R-HSA-168930_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-9014342","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:R-HSA-450152_R-HSA-9014342","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014342_RO_0002233_R-HSA-450152_R-HSA-9014342_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-9014342_RO_0002233_R-HSA-450152_R-HSA-9014342_Reactome_R-HSA-9014342","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-168915","property":"RO:0002234","property-label":"RO:0002234","object":"gomodel:R-HSA-937016_R-HSA-168915","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168915_RO_0002234_R-HSA-937016_R-HSA-168915_Reactome_R-HSA-168915","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168915_RO_0002234_R-HSA-937016_R-HSA-168915_Reactome_R-HSA-937041","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-168930","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:R-HSA-168907_R-HSA-168930","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168930_RO_0002233_R-HSA-168907_R-HSA-168930_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168930_RO_0002233_R-HSA-168907_R-HSA-168930_Reactome_R-HSA-168930","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]},{"subject":"gomodel:R-HSA-168915","property":"BFO:0000066","property-label":"BFO:0000066","object":"gomodel:reaction_R-HSA-168915_location_lociGO_0005829","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168915_BFO_0000066_reaction_R-HSA-168915_location_lociGO_0005829_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"},{"key":"comment","value":"Occurs In Rule. This relation was asserted based on the location of the enabling molecule. "}]},{"subject":"gomodel:R-HSA-168930","property":"RO:0002233","property-label":"RO:0002233","object":"gomodel:R-HSA-168651_R-HSA-168930","annotations":[{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168930_RO_0002233_R-HSA-168651_R-HSA-168930_Reactome_R-HSA-168927","value-type":"IRI"},{"key":"evidence","value":"gomodel:ev_w_id_R-HSA-168930_RO_0002233_R-HSA-168651_R-HSA-168930_Reactome_R-HSA-168930","value-type":"IRI"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"}]}],"annotations":[{"key":"state","value":"development"},{"key":"contributor","value":"GOC:reactome_curators"},{"key":"date","value":"2023-06-21"},{"key":"title","value":"TICAM1, RIP1-mediated IKK complex recruitment - imported from: Reactome"},{"key":"providedBy","value":"https://reactome.org"},{"key":"comment","value":"For logical inference, import the integrated tbox ontology http://purl.obolibrary.org/obo/go/extensions/go-lego-reacto.owl"},{"key":"comment","value":"Imported from Reactome: https://reactome.org/content/detail/R-HSA-168927"},{"key":"comment","value":"http://www.reactome.org"},{"key":"https://w3id.org/biolink/vocab/in_taxon","value":"NCBITaxon:9606","value-type":"IRI"}]}